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  • 筋骨草甾酮C

    Ajugasterone C

    筋骨草甾酮C
    产品编号 CFN90616
    CAS编号 23044-80-6
    分子式 = 分子量 C27H44O7 = 480.64
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Steroids
    植物来源 The herbs of Ajuga ciliata Bunge.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    筋骨草甾酮C CFN90616 23044-80-6 1mg QQ客服:1457312923
    筋骨草甾酮C CFN90616 23044-80-6 5mg QQ客服:1457312923
    筋骨草甾酮C CFN90616 23044-80-6 10mg QQ客服:1457312923
    筋骨草甾酮C CFN90616 23044-80-6 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universidade Federal de Pernambuco (UFPE) (Brazil)
  • Univerzita Karlova v Praze (Czech Republic)
  • University of Hawaii Cancer Center (USA)
  • The Ohio State University (USA)
  • Washington State University (USA)
  • Hamdard University (India)
  • University of East Anglia (United Kingdom)
  • Universidad de Ciencias y Artes de Chiapas (Mexico)
  • University of Hertfordshire (United Kingdom)
  • Gyeongsang National University (Korea)
  • Istanbul University (Turkey)
  • University of Melbourne (Australia)
  • Rio de Janeiro State University (Brazil)
  • Georgia Institute of Technology (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Evid Based Complement Alternat Med.2022, 9767292,2.
  • JPC-Journal of Planar Chromatography 2017, 30(2)
  • RSC Advances2017, 86
  • J Exp Bot.2016, 67(12):3777-88
  • J Nat Med.2022, 76(1):59-67.
  • Pharmacognosy Magazine2017, 13(52):868-874
  • Nanjing University of Chinese Medicine2022, 345930.
  • Org Biomol Chem.2017, 15(31):6483-6492
  • J Cell Biochem.2018, 119(2):2231-2239
  • J Ethnopharmacol.2022, 289:115018.
  • Chem Pharm Bull (Tokyo).2019, 67(11):1242-1247
  • Exp Biol Med (Maywood).2019, 244(18):1665-1679
  • Environ Toxicol.2019, 34(4):513-520.
  • Revista Brasileira de Farmacognosia2021, 31:794-804.
  • Acta Physiologiae Plantarum2015, 37:1736
  • Sci Rep. 2018, 10590
  • Molecules.2019, 24(19):E3417
  • J Ethnopharmacol.2017, 198:87-90
  • Environ Toxicol Pharmacol.2019, 66:109-115
  • In Vivo.2022, 36(3):1136-1143.
  • Food Funct.2022, doi: 10.1039
  • Front Pharmacol.2022, 13:806869.
  • J Adv Res.2019, 17:85-94
  • ...
  • 生物活性
    Description: Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats.
    Targets: Immunology & Inflammation related
    In vivo:
    Planta Med. 2013 Jan;79(1):52-9.
    Phytoecdysteroids from the stem bark of Vitex doniana and their anti-inflammatory effects.[Pubmed: 23150078 ]
    With reference to the ethnopharmacological significance of Vitex doniana Sweet (Lamiaceae) leaves in the treatment of stomach and rheumatic pains as well as inflammatory disorders, biological studies on its stem bark extracts have also reported anti-inflammatory and analgesic activities, with no attempt to identify the active components.
    METHODS AND RESULTS:
    Chromatographic and spectroscopic procedures identified three new phytoecdysteroids: 21-hydroxyshidasterone (1), 11β-hydroxy-20-deoxyshidasterone (2), and 2,3-acetonide-24-hydroxyecdysone (3) from the stem bark methanol extracts along with known ecdysteroids shidasterone (4), Ajugasterone C (5), 24-hydroxyecdysone (6), and 11β,24-hydroxyecdysone (7). The compounds (1-7) showed significant (p ≤ 0.05) inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats.
    CONCLUSIONS:
    These results suggest a possible contribution of ecdysteroids to the anti-inflammatory effect of some V. doniana stem bark extracts.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0806 mL 10.4028 mL 20.8056 mL 41.6112 mL 52.014 mL
    5 mM 0.4161 mL 2.0806 mL 4.1611 mL 8.3222 mL 10.4028 mL
    10 mM 0.2081 mL 1.0403 mL 2.0806 mL 4.1611 mL 5.2014 mL
    50 mM 0.0416 mL 0.2081 mL 0.4161 mL 0.8322 mL 1.0403 mL
    100 mM 0.0208 mL 0.104 mL 0.2081 mL 0.4161 mL 0.5201 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    27-羟基胆固醇; 27-Hydroxycholesterol CFN90609 20380-11-4 C27H46O2 = 402.65 10mg QQ客服:3257982914
    胆甾-4,6-二烯-3-醇; Cholest-4,6-diene-3-ol CFN91582 14214-69-8 C27H44O = 384.6 5mg QQ客服:3257982914
    松甾酮A; Ponasterone A CFN99419 13408-56-5 C27H44O6 = 464.6 5mg QQ客服:3257982914
    筋骨草甾酮C; Ajugasterone C CFN90616 23044-80-6 C27H44O7 = 480.64 5mg QQ客服:3257982914
    牛膝甾酮; Inokosterone CFN92515 15130-85-5 C27H44O7 = 480.6 5mg QQ客服:1413575084
    25S-牛膝甾酮; 25S-Inokosterone CFN93571 19595-18-7 C27H44O7 = 480.6 5mg QQ客服:3257982914
    25R-牛膝甾酮; 25R-Inokosterone CFN93572 19682-38-3 C27H44O7 = 480.6 5mg QQ客服:2056216494
    土克甾酮; Turkesterone CFN90217 41451-87-0 C27H44O8 = 496.64 5mg QQ客服:1457312923
    蜕皮激素; Ecdysone CFN90487 3604-87-3 C27H44O6 = 464.63 5mg QQ客服:215959384
    漏芦甾酮 B; Rhapontisterone B CFN90522 698975-64-3 C27H44O7 = 480.63 5mg QQ客服:1413575084

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