Info: Read More
  • 中药标准品生产商,产品定制服务
  • Vitexolide D

    Vitexolide D

    Vitexolide D
    产品编号 CFN96446
    CAS编号 1788090-69-6
    分子式 = 分子量 C20H30O3 = 318.45
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Diterpenoids
    植物来源 The herbs of Vitex vestita
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Vitexolide D CFN96446 1788090-69-6 1mg QQ客服:1413575084
    Vitexolide D CFN96446 1788090-69-6 5mg QQ客服:1413575084
    Vitexolide D CFN96446 1788090-69-6 10mg QQ客服:1413575084
    Vitexolide D CFN96446 1788090-69-6 20mg QQ客服:1413575084
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Siksha O Anusandhan University (India)
  • Universidad de Antioquia (Colombia)
  • Auburn University (USA)
  • Helmholtz Zentrum München (Germany)
  • Utrecht University (Netherlands)
  • National Chung Hsing University (Taiwan)
  • Melbourne University (Australia)
  • Institute of Chinese Materia Medica (China)
  • Wroclaw Medical University (Poland)
  • Chulalongkorn University (Thailand)
  • University of Wuerzburg (Germany)
  • University of Ioannina (Greece)
  • University of Canterbury (New Zealand)
  • University of Otago (New Zealand)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Kyung Hee University2024, rs-3888374
  • Front Microbiol.2019, 10:2806
  • Pharmacol Rep.2018, 70(6):1195-1201
  • J Am Soc Mass Spectrom.2021, 32(9):2451-2462.
  • J Enzyme Inhib Med Chem.2019, 34(1):134-143
  • J Pharm Biomed Anal.2018, 151:32-41
  • J Chromatogr A.2017, 1518:46-58
  • J Ethnopharmacol.2020, 269:113752.
  • Food Chem.2022, 378:131975.
  • SBRAS2016, 12
  • Toxicological Research2020, doi: 10.1007.
  • Asian Journal of Chemistry2014, 26(8):2425
  • J Pharm Biomed Anal.2019, 164:119-127
  • Sci Rep. 2017, 12953(7)
  • Org Biomol Chem.2017, 15(31):6483-6492
  • Biomolecules.2022, 12(12):1754.
  • Phytomedicine.2022, 99:153997.
  • Food Chem.2018, 262:78-85
  • Processes2021, 9(5),831.
  • Planta Medica International2022, 9(01):e108-e115.
  • Molecules.2019, 24(6):E1155
  • Phytother Res.2015, 29(7):1088-96
  • Cell Rep.2022, 39(1):110643.
  • ...
  • 生物活性
    Description: Vitexolide D shows moderate antibacterial activity against a panel of 46 Gram-positive strains. It also shows cytotoxic activities against the HCT-116 cancer cell line and human fetal lung fibroblast MRC5 cell line (1 < IC50s < 10 uM).
    Targets: Antifection
    In vitro:
    J Nat Prod. 2015 Jun 26;78(6):1348-56.
    Antibacterial Labdane Diterpenoids from Vitex vestita.[Pubmed: 26034885 ]

    METHODS AND RESULTS:
    Bioassay-guided purification of the dichloromethane extract of the leaves of the Malaysian species Vitex vestita, led to the isolation of six new labdane-type diterpenoids, namely, 12-epivitexolide A (2), vitexolides B and C (3 and 4), vitexolide E (8), and vitexolins A and B (5 and 6), along with six known compounds, vitexolide A (1) and Vitexolide D (7), acuminolide (9), 3β-hydroxyanticopalic acid (10), 8α-hydroxyanticopalic acid (11), and 6α-hydroxyanticopalic acid (12). Their structures were elucidated on the basis of 1D and 2D NMR analyses and HRMS experiments. Both variable-temperature NMR spectroscopic studies and chemical modifications were performed to investigate the dynamic epimerization of the γ-hydroxybutenolide moiety of compounds 1-4. Compounds were assayed against a panel of 46 Gram-positive strains.
    CONCLUSIONS:
    Vitexolide A (1) exhibited the most potent antibacterial activity with minimal inhibitory concentration values ranging from 6 to 96 μM, whereas compounds 2 and 6-9 showed moderate antibacterial activity. The presence of a β-hydroxyalkyl-γ-hydroxybutenolide subunit contributed significantly to antibacterial activity. Compounds 1-4 and 6-9 showed cytotoxic activities against the HCT-116 cancer cell line (1 < IC50s < 10 μM) and human fetal lung fibroblast MRC5 cell line (1 < IC50s < 10 μM for compounds 1, 2, 7, 8, and 9).
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.1402 mL 15.7011 mL 31.4021 mL 62.8042 mL 78.5053 mL
    5 mM 0.628 mL 3.1402 mL 6.2804 mL 12.5608 mL 15.7011 mL
    10 mM 0.314 mL 1.5701 mL 3.1402 mL 6.2804 mL 7.8505 mL
    50 mM 0.0628 mL 0.314 mL 0.628 mL 1.2561 mL 1.5701 mL
    100 mM 0.0314 mL 0.157 mL 0.314 mL 0.628 mL 0.7851 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Andropanolide; Andropanolide CFN97600 869807-57-8 C20H30O5 = 350.45 5mg QQ客服:1413575084
    穿心莲内酯; Andrographolide CFN98923 5508-58-7 C20H30O5 = 350.5 20mg QQ客服:2056216494
    14-去氧-11,12-二去氢穿心莲内酯; 14-Deoxy-11,12-didehydroandrographolide CFN98666 42895-58-9 C20H28O4 = 332.4 20mg QQ客服:215959384
    脱水穿心莲内酯; Dehydroandrographolide CFN99770 134418-28-3 C20H28O4 = 332.43 20mg QQ客服:3257982914
    14-去氧穿心莲内酯; 14-Deoxyandrographolide CFN92802 4176-97-0 C20H30O4 = 334.45 10mg QQ客服:1457312923
    去氧穿心莲内酯; Deoxyandrographolide CFN90518 79233-15-1 C20H30O4 = 334.45 20mg QQ客服:215959384
    14-去氧基-17-羟基穿心莲内酯; 14-Deoxy-17-hydroxyandrographolide CFN97601 869384-82-7 C20H32O5 = 352.47 5mg QQ客服:2159513211
    14-去氧基-11-羟基穿心莲内酯; 14-Deoxy-11-hydroxyandrographolide CFN97815 160242-09-1 C20H30O5 = 350.45 5mg QQ客服:215959384
    14-去氧-12-羟基穿心莲内酯; 14-Deoxy-12-hydroxyandrographolide CFN97785 219721-33-2 C20H30O5 = 350.45 5mg QQ客服:2159513211
    Vitexolide D; Vitexolide D CFN96446 1788090-69-6 C20H30O3 = 318.45 5mg QQ客服:3257982914

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产