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  • 14-去氧基-11-羟基穿心莲内酯

    14-Deoxy-11-hydroxyandrographolide

    14-去氧基-11-羟基穿心莲内酯
    产品编号 CFN97815
    CAS编号 160242-09-1
    分子式 = 分子量 C20H30O5 = 350.45
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Diterpenoids
    植物来源 The herbs of Andrographis paniculata (Burm. f.) Nees
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    14-去氧基-11-羟基穿心莲内酯 CFN97815 160242-09-1 1mg QQ客服:1457312923
    14-去氧基-11-羟基穿心莲内酯 CFN97815 160242-09-1 5mg QQ客服:1457312923
    14-去氧基-11-羟基穿心莲内酯 CFN97815 160242-09-1 10mg QQ客服:1457312923
    14-去氧基-11-羟基穿心莲内酯 CFN97815 160242-09-1 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Acta Agriculturae Scandinavica2015, 381-383
  • Nutrients.2022, 14(16):3393.
  • J Sep Sci.2020, 201901140
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  • Heliyon.2023, 9:e21652.
  • LWT-Food Science and Technology2017, 75:488-496
  • Food Chem Toxicol.2023, 176:113802.
  • Front Pharmacol.2021, 12:764297.
  • Molecules.2020, 25(7):1625.
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  • Evid Based Complement Alternat Med.2022, 2022:3483511
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  • ...
  • 生物活性
    Description: 14-Deoxy-11-hydroxyandrographolide shows potent cell differentiation-inducing activity towards mouse myeloid leukemia (M1) cells.
    In vitro:
    Chem Pharm Bull (Tokyo). 1994 Jun;42(6):1216-25.
    Cell differentiation-inducing diterpenes from Andrographis paniculata Nees.[Pubmed: 8069972]
    The methanol extract of the aerial part of Andrographis paniculata Nees showed potent cell differentiation-inducing activity on mouse myeloid leukemia (M1) cells.
    METHODS AND RESULTS:
    From the ethyl acetate-soluble fraction of the methanol extract, six new diterpenoids of ent-labdane type, 14-epi-andrographolide (3), isoandrographolide (4), 14-deoxy-12-methoxyandrographolide (7), 12-epi-14-deoxy-12-methoxyandrographolide (8), 14-deoxy-12-hydroxyandrographolide (9) and 14-Deoxy-11-hydroxyandrographolide (10) as well as two new diterpene glucosides, 14-deoxy-11,12-didehydroandrographi-side (12) and 6'-acetylneoandrographolide (14), and four new diterpene dimers, bis-andrograpolides A (15), B (16), C (17) and D (18), were isolated along with six known compounds. The structures of the diterpenoids were determined by means of spectral methods.
    CONCLUSIONS:
    Some of these compounds showed potent cell differentiation-inducing activity towards M1 cells.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8535 mL 14.2674 mL 28.5347 mL 57.0695 mL 71.3369 mL
    5 mM 0.5707 mL 2.8535 mL 5.7069 mL 11.4139 mL 14.2674 mL
    10 mM 0.2853 mL 1.4267 mL 2.8535 mL 5.7069 mL 7.1337 mL
    50 mM 0.0571 mL 0.2853 mL 0.5707 mL 1.1414 mL 1.4267 mL
    100 mM 0.0285 mL 0.1427 mL 0.2853 mL 0.5707 mL 0.7134 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Andropanolide; Andropanolide CFN97600 869807-57-8 C20H30O5 = 350.45 5mg QQ客服:2159513211
    穿心莲内酯; Andrographolide CFN98923 5508-58-7 C20H30O5 = 350.5 20mg QQ客服:3257982914
    14-去氧-11,12-二去氢穿心莲内酯; 14-Deoxy-11,12-didehydroandrographolide CFN98666 42895-58-9 C20H28O4 = 332.4 20mg QQ客服:2159513211
    脱水穿心莲内酯; Dehydroandrographolide CFN99770 134418-28-3 C20H28O4 = 332.43 20mg QQ客服:2056216494
    14-去氧穿心莲内酯; 14-Deoxyandrographolide CFN92802 4176-97-0 C20H30O4 = 334.45 10mg QQ客服:215959384
    去氧穿心莲内酯; Deoxyandrographolide CFN90518 79233-15-1 C20H30O4 = 334.45 20mg QQ客服:1457312923
    14-去氧基-17-羟基穿心莲内酯; 14-Deoxy-17-hydroxyandrographolide CFN97601 869384-82-7 C20H32O5 = 352.47 5mg QQ客服:1413575084
    14-去氧基-11-羟基穿心莲内酯; 14-Deoxy-11-hydroxyandrographolide CFN97815 160242-09-1 C20H30O5 = 350.45 5mg QQ客服:3257982914
    14-去氧-12-羟基穿心莲内酯; 14-Deoxy-12-hydroxyandrographolide CFN97785 219721-33-2 C20H30O5 = 350.45 5mg QQ客服:3257982914
    Vitexolide D; Vitexolide D CFN96446 1788090-69-6 C20H30O3 = 318.45 5mg QQ客服:3257982914

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