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    Lucialdehyde B

    Lucialdehyde B

    Lucialdehyde B
    产品编号 CFN90305
    CAS编号 480439-84-7
    分子式 = 分子量 C30H44O3 = 452.67
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruit body of Ganoderma lucidum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Lucialdehyde B CFN90305 480439-84-7 1mg QQ客服:1413575084
    Lucialdehyde B CFN90305 480439-84-7 5mg QQ客服:1413575084
    Lucialdehyde B CFN90305 480439-84-7 10mg QQ客服:1413575084
    Lucialdehyde B CFN90305 480439-84-7 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Stirling (United Kingdom)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Food Chem.2016, 191:81-90
  • Kor. J. Pharmacogn.2016, 47(1):62-72
  • Universidade Estadual Paulista2017, 11449
  • Cytotechnology.2017, 69(5):765-773
  • Front Plant Sci.2017, 8:723
  • J Cell Biochem.2018, 119(2):2231-2239
  • International Food Research Journal2018, 25(6):2560-2571
  • J Sep Sci.2018, 41(9):1938-1946
  • J Agric Food Chem.2018, 66(1):351-358
  • Nat Commun.2019, 10(1):2745
  • Nutrients.2019, 11(11):E2694
  • Postharvest Biol Tec2019, 149:18-26
  • Exp Ther Med.2019, 18(6):4388-4396
  • Molecules.2019, 24(2):329
  • Comput Biol Chem.2019, 83:107096
  • J Sep Sci.2020, 201901140
  • J of App. Res. on Med&Aromatic Plants2020, 100291.
  • Molecules.2020, 25(15):3353.
  • Molecules.2020, 25(18):4283.
  • Molecules.2020, 25(23):5556.
  • J Nat Med.2020, 74(3):550-560.
  • Reprod Toxicol.2020, 96:1-10.
  • Appl. Sci.2021, 11(1),14.
  • ...
  • 生物活性
    Description: Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines.
    Targets: HSV | Integrase
    In vitro:
    J Nat Prod. 2005 Dec;68(12):1728-31.
    Antiviral Terpenoid Constituents of Ganoderma pfeifferi.[Pubmed: 16378363]

    METHODS AND RESULTS:
    Four sterols and 10 triterpenes were isolated from the fruiting bodies of Ganoderma pfeifferi, including the three new triterpenes 3,7,11-trioxo-5alpha-lanosta-8,24-diene-26-al (lucialdehyde D, 1), 5alpha-lanosta-8,24-diene-26-hydroxy-3,7-dione (ganoderone A, 2), and 5alpha-lanosta-8-ene-24,25-epoxy-26-hydroxy-3,7-dione (ganoderone C, 3). The structures of 1-3 were determined on the basis of spectroscopic evidence. Antibacterial, antifungal, and antiviral activity were studied for some of the isolated compounds.
    CONCLUSIONS:
    Ganoderone A (2), Lucialdehyde B (4), and ergosta-7,22-dien-3beta-ol (7) were found to exhibit potent inhibitory activity against herpes simplex virus.
    Chem Pharm Bull (Tokyo). 2002 Jun;50(6):837-40.
    New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells.[Pubmed: 12045343]
    Three new lanostante-type triterpene aldehydes, named lucialdehydes A-C (1-3), were isolated from the fruiting bodies of Ganoderma lucidum, together with ganodermanonol (4), ganodermadiol (5), ganodermanondiol (6), ganodermanontriol (7), ganoderic acid A (8), ganoderic acid B8 (9), and ganoderic acid C1 (10).
    METHODS AND RESULTS:
    The structures of the new triterpenes were determined as (24E)-3 beta-hydroxy-5 alpha-lanosta-7,9(11),24-trien-26-al (1), (24E)-3,7-dioxo-5 alpha-lanosta-8,24-dien-26-al (2), and (24E)-3 beta-hydroxy-7-oxo-5 alpha-lanosta-8,24-dien-26-al (3), respectively, by spectroscopic means. The cytotoxicity of the compounds isolated from the ganoderma mushroom was tested in vitro against Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines. Lucialdehyde B, Lucialdehyde C (2, 3), ganodermanonol (4) and ganodermanondiol (6) showed cytotoxic effects on tested tumor cells.
    CONCLUSIONS:
    Of the compounds, lucialdehyde C (3) exhibited the most potent cytotoxicity against LLC, T-47D, Sarcoma 180, and Meth-A tumor cells with ED(50) values of 10.7, 4.7, 7.1, and 3.8 microg/ml, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2091 mL 11.0456 mL 22.0911 mL 44.1823 mL 55.2279 mL
    5 mM 0.4418 mL 2.2091 mL 4.4182 mL 8.8365 mL 11.0456 mL
    10 mM 0.2209 mL 1.1046 mL 2.2091 mL 4.4182 mL 5.5228 mL
    50 mM 0.0442 mL 0.2209 mL 0.4418 mL 0.8836 mL 1.1046 mL
    100 mM 0.0221 mL 0.1105 mL 0.2209 mL 0.4418 mL 0.5523 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Lucidal; Lucidal CFN92234 252351-96-5 C30H46O3 = 454.7 5mg QQ客服:2159513211
    Lucialdehyde B; Lucialdehyde B CFN90305 480439-84-7 C30H44O3 = 452.67 5mg QQ客服:2932563308
    Lucidumol A; Lucidumol A CFN95059 217476-73-8 C30H48O4 = 472.7 5mg QQ客服:2932563308
    灵芝醇A; Ganoderol A CFN99065 104700-97-2 C30H46O2 = 438.7 5mg QQ客服:2932563308
    灵芝醇F; Ganoderiol F CFN99244 114567-47-4 C30H46O3 = 454.7 5mg QQ客服:2932563308
    灵芝萜酮二醇 ; Ganodermanondiol CFN99085 107900-76-5 C30H48O3 = 456.7 5mg QQ客服:2932563308
    灵芝醇A; Ganoderiol A CFN80461 106518-61-0 C30H50O4 = 474.37 5mg QQ客服:2056216494
    灵芝马酮; Ganodermanontriol CFN99077 106518-63-2 C30H48O4 = 472.7 5mg QQ客服:2932563308
    Lucialdehyde A; Lucialdehyde A CFN90304 420781-84-6 C30H46O2 = 438.69 5mg QQ客服:1413575084
    灵芝醛A; Ganoderal A CFN90306 104700-98-3 C30H44O2 = 436.68 5mg QQ客服:1413575084

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