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    Lucialdehyde A

    Lucialdehyde A

    Lucialdehyde A
    产品编号 CFN90304
    CAS编号 420781-84-6
    分子式 = 分子量 C30H46O2 = 438.69
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruit body of Ganoderma lucidum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Lucialdehyde A CFN90304 420781-84-6 1mg QQ客服:2159513211
    Lucialdehyde A CFN90304 420781-84-6 5mg QQ客服:2159513211
    Lucialdehyde A CFN90304 420781-84-6 10mg QQ客服:2159513211
    Lucialdehyde A CFN90304 420781-84-6 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Aarhus University (Denmark)
  • Agricultural Research Organization (ARO) (Israel)
  • Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)
  • Universite de Lille1 (France)
  • Gyeongsang National University (Korea)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • University of Wisconsin-Madison (USA)
  • University of Wollongong (Australia)
  • Universidade de Franca (Brazil)
  • Florida International University (USA)
  • University Medical Center Mainz (Germany)
  • University of Amsterdam (Netherlands)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Asian Journal of Chemistry2014, 26(8):2425
  • J Ethnopharmacol.2016, 194:219-227
  • Food Sci Biotechnol.2016, 25(5):1437-1442
  • HortTechnology2016, 26(6):816-819
  • Jour. of Stored Pro & Postharvest Res.2016, 7(3):32-36
  • Evid Based Complement Alternat Med.2017, 2017:7383104
  • Biochem Biophys Res Commun.2017, 482(4):1095-1101
  • Cytotechnology.2017, 69(5):765-773
  • Front Aging Neurosci.2018, 10:269
  • Sci Rep. 2018, 10590
  • Int J Mol Sci.2018, 19(9):E2528
  • Sci Adv.2018, 4(10)
  • Front Immunol.2018, 9:2655
  • Nutrients.2019, 11(11):E2694
  • Molecules.2019, 24(20):3755
  • Med Sci Monit.2019, 25:9499-9508
  • J Funct Foods2019, 54:449-456
  • Anal Biochem.2019, 569:10-15
  • J Mater Chem B.2019, 7(39):5896-5919
  • Crystals2020, 10(3), 206.
  • Asian Pac J Tropical Bio.2020, 10(6):239-247
  • Int J Mol Med.2020, 45(5):1514-1524.
  • Reprod Toxicol.2020, 96:1-10.
  • ...
  • 生物活性
    Description: Lucialdehydes A-C (1-3) are new lanostante-type triterpene aldehydes, show cytotoxic effects on tumor cells, including Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines.
    In vitro:
    Chem. Pharm. Bull., 2002, 50(6):837-40.
    New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells.[Pubmed: 12045343]

    METHODS AND RESULTS:
    Three new lanostante-type triterpene aldehydes, named Lucialdehyde A-C (1-3), were isolated from the fruiting bodies of Ganoderma lucidum, together with ganodermanonol (4), ganodermadiol (5), ganodermanondiol (6), ganodermanontriol (7), ganoderic acid A (8), ganoderic acid B8 (9), and ganoderic acid C1 (10). The structures of the new triterpenes were determined as (24E)-3 beta-hydroxy-5 alpha-lanosta-7,9(11),24-trien-26-al (1), (24E)-3,7-dioxo-5 alpha-lanosta-8,24-dien-26-al (2), and (24E)-3 beta-hydroxy-7-oxo-5 alpha-lanosta-8,24-dien-26-al (3), respectively, by spectroscopic means. The cytotoxicity of the compounds isolated from the ganoderma mushroom was tested in vitro against Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines. Lucialdehydes B, C (2, 3), ganodermanonol (4) and ganodermanondiol (6) showed cytotoxic effects on tested tumor cells.
    CONCLUSIONS:
    Of the compounds, lucialdehyde C (3) exhibited the most potent cytotoxicity against LLC, T-47D, Sarcoma 180, and Meth-A tumor cells with ED(50) values of 10.7, 4.7, 7.1, and 3.8 microg/ml, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2795 mL 11.3976 mL 22.7951 mL 45.5903 mL 56.9879 mL
    5 mM 0.4559 mL 2.2795 mL 4.559 mL 9.1181 mL 11.3976 mL
    10 mM 0.228 mL 1.1398 mL 2.2795 mL 4.559 mL 5.6988 mL
    50 mM 0.0456 mL 0.228 mL 0.4559 mL 0.9118 mL 1.1398 mL
    100 mM 0.0228 mL 0.114 mL 0.228 mL 0.4559 mL 0.5699 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Lucialdehyde A; Lucialdehyde A CFN90304 420781-84-6 C30H46O2 = 438.69 5mg QQ客服:2056216494
    灵芝醛A; Ganoderal A CFN90306 104700-98-3 C30H44O2 = 436.68 5mg QQ客服:2932563308
    灵芝酮A; Ganoderone A CFN90303 873061-79-1 C30H48O3 = 456.70 5mg QQ客服:1413575084
    赤芝二醇; Lucidadiol CFN96840 252351-95-4 C30H48O3 = 456.71 5mg QQ客服:2932563308
    Lucidal; Lucidal CFN92234 252351-96-5 C30H46O3 = 454.7 5mg QQ客服:2932563308
    Lucialdehyde B; Lucialdehyde B CFN90305 480439-84-7 C30H44O3 = 452.67 5mg QQ客服:2932563308
    Lucidumol A; Lucidumol A CFN95059 217476-73-8 C30H48O4 = 472.7 5mg QQ客服:1413575084
    灵芝醇A; Ganoderol A CFN99065 104700-97-2 C30H46O2 = 438.7 5mg QQ客服:1413575084
    灵芝醇F; Ganoderiol F CFN99244 114567-47-4 C30H46O3 = 454.7 5mg QQ客服:2932563308
    灵芝萜酮二醇 ; Ganodermanondiol CFN99085 107900-76-5 C30H48O3 = 456.7 5mg QQ客服:2159513211

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