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  • 大豆脑苷II

    Soyacerebroside II

    大豆脑苷II
    产品编号 CFN99250
    CAS编号 115074-93-6
    分子式 = 分子量 C40H75NO9 = 714.0
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Cerebrosides
    植物来源 The fruits of Glycine max
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    大豆脑苷II CFN99250 115074-93-6 1mg QQ客服:1413575084
    大豆脑苷II CFN99250 115074-93-6 5mg QQ客服:1413575084
    大豆脑苷II CFN99250 115074-93-6 10mg QQ客服:1413575084
    大豆脑苷II CFN99250 115074-93-6 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Bonn (Germany)
  • Instituto Politécnico de Bragan?a (Portugal)
  • University of Melbourne (Australia)
  • Universidad Veracuzana (Mexico)
  • Warszawski Uniwersytet Medyczny (Poland)
  • Universidade de Franca (Brazil)
  • University of Oslo (Norway)
  • Martin Luther University of Halle-Wittenberg (Germany)
  • Universite Libre de Bruxelles (Belgium)
  • University of Illinois at Chicago (USA)
  • University of Limpopo (South Africa)
  • Institute of Tropical Disease Universitas Airlangga (Indonesia)
  • Max Rubner-Institut (MRI) (Germany)
  • Korea Institute of Oriental Medicine (Korea)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Cells.2021, 10(10):2633.
  • Cancers (Basel).2021, 13(6):1432.
  • Molecules.2021, 26(19):6032.
  • Chemistry of Plant Materials.2016, 33-46
  • Ind Crops Prod.2015, 67:185-191
  • Processes2021, 9(11),2065.
  • J Biol Chem.2021, 297(6):101362.
  • Biosci Rep.2018, 38(4)
  • Molecules.2017, 22(3)
  • Molecules.2019, 24(7):E1290
  • Nat Prod Commun.2018, 10.1177
  • Evid Based Complement Alternat Med.2017, 2017:7383104
  • Plants (Basel).2021, 10(11):2317.
  • Cells.2022, 11(8), 1311.
  • Food Chem.2016, 191:81-90
  • Primary and Industrial.2018, 52(11)
  • Cell Rep.2020, 32(11):108158.
  • Oncol Lett.2020, 20(4):122.
  • J Ethnopharmacol.2019, 244:112074
  • Pharmaceutics.2021, 13(2):187.
  • Fitoterapia.2015, 100:179-86
  • J Int Med Res.2021, 49(7):3000605211032849.
  • Antioxidants.2022, 11(3):592.
  • ...
  • 生物活性
    Description: Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion. Soyacerebrosides I and II have modulating the cellular immune response effects, they show obvious inhibitory activity on IL-18 secretion in human peripheral blood mononuclear cells (PBMC).
    Targets: IL Receptor | Calcium Channel
    In vitro:
    Chem Pharm Bull (Tokyo). 1990 Nov;38(11):2933-8.
    Sphingolipids and glycerolipids. I. Chemical structures and ionophoretic activities of soya-cerebrosides I and II from soybean.[Pubmed: 2085876]

    METHODS AND RESULTS:
    Two glycosphingolipids named soya-cerebrosides I and II were isolated from soybean, the seeds of Glycine max Merrill (Leguminosae), and their chemical structures have been elucidated on the basis of physicochemical evidence and several chemical degradation reactions.
    CONCLUSIONS:
    By using a newly constructed liquid membrane-type apparatus (W-08) for measurement of ion-transport and ion-binding activities and by employing a method using human erythrocyte membranes for measurement of ion-permeability, it has been found that Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion.
    Lipids. 2009 Aug;44(8):759-63.
    An isomeric mixture of novel cerebrosides isolated from Impatiens pritzellii reduces lipopolysaccharide-induced release of IL-18 from human peripheral blood mononuclear cells.[Pubmed: 19609788]
    An isomeric mixture of two cerebrosides, soyacerebroside I and Soyacerebroside II, was isolated from an ethno drug, the rhizomes of Impatiens pritzellii Hook. f. var. hupehensis Hook. f., and their structures were identified by spectroscopic (NMR, MS) analysis.
    METHODS AND RESULTS:
    In order to determine the immunomodulatory activities of soya-cerebrosides I and II, the effects of the mixture of cerebrosides (MC) on cytotoxicity of human peripheral blood mononuclear cells (PBMC) and the inhibitory activities to lipopolysaccharide (LPS)-induced interleukin (IL)-18 in PBMC were studied. The MC at concentrations of 10 and 1 microM, without toxicity to PBMC in 24 h, showed obvious inhibitory activity on IL-18 secretion.
    CONCLUSIONS:
    Because of this effect of modulating the cellular immune response, soya-cerebrosides I and II were considered to be the active substances of this ethno drug.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.4006 mL 7.0028 mL 14.0056 mL 28.0112 mL 35.014 mL
    5 mM 0.2801 mL 1.4006 mL 2.8011 mL 5.6022 mL 7.0028 mL
    10 mM 0.1401 mL 0.7003 mL 1.4006 mL 2.8011 mL 3.5014 mL
    50 mM 0.028 mL 0.1401 mL 0.2801 mL 0.5602 mL 0.7003 mL
    100 mM 0.014 mL 0.07 mL 0.1401 mL 0.2801 mL 0.3501 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    三七草酰胺II; Gynuramide II CFN98367 295803-03-1 C42H83NO5 = 682.1 5mg QQ客服:215959384
    (2R)-2-(乙酰氧基)-N-[(1S,2S,3R)-2,3-双(乙酰氧基)-1-[(乙酰氧基)甲基]十七烷基]二十四碳酰胺; 2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate CFN98439 340702-68-3 C50H93NO9 = 852.3 5mg QQ客服:1148253675
    (2S,3S,4R,2'R)-2-(2'-羟基二十四碳酰氨基)十八烷-1,3,4-三醇; 2-(2'-Hydroxytetracosanoylamino)-octadecane-1,3,4-triol CFN99649 154801-30-6 C42H85NO5 = 684.1 5mg QQ客服:2159513211
    大豆脑苷I; Soyacerebroside I CFN99242 114297-20-0 C40H75NO9 = 714.0 5mg QQ客服:3257982914
    大豆脑苷II; Soyacerebroside II CFN99250 115074-93-6 C40H75NO9 = 714.0 5mg QQ客服:2159513211
    Momor-脑苷脂I; Momor-cerebroside I CFN97031 606125-07-9 C48H93NO10 = 844.3 5mg QQ客服:2159513211
    脑苷脂B; Cerebroside B CFN97455 88642-46-0 C41H77NO9 = 728.1 5mg QQ客服:3257982914

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