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  • (2S,3S,4R,2'R)-2-(2'-羟基二十四碳酰氨基)十八烷-1,3,4-三醇

    2-(2'-Hydroxytetracosanoylamino)-octadecane-1,3,4-triol

    (2S,3S,4R,2'R)-2-(2'-羟基二十四碳酰氨基)十八烷-1,3,4-三醇
    产品编号 CFN99649
    CAS编号 154801-30-6
    分子式 = 分子量 C42H85NO5 = 684.1
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Cerebrosides
    植物来源 The fruits of Evodia rutaecarpa
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    (2S,3S,4R,2'R)-2-(2'-羟基二十四碳酰氨基)十八烷-1,3,4-三醇 CFN99649 154801-30-6 1mg QQ客服:2159513211
    (2S,3S,4R,2'R)-2-(2'-羟基二十四碳酰氨基)十八烷-1,3,4-三醇 CFN99649 154801-30-6 5mg QQ客服:2159513211
    (2S,3S,4R,2'R)-2-(2'-羟基二十四碳酰氨基)十八烷-1,3,4-三醇 CFN99649 154801-30-6 10mg QQ客服:2159513211
    (2S,3S,4R,2'R)-2-(2'-羟基二十四碳酰氨基)十八烷-1,3,4-三醇 CFN99649 154801-30-6 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • University of Wuerzburg (Germany)
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  • Kazusa DNA Research Institute (Japan)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Applied Biological Chem. 2020, 26(63).
  • Food Chem. 2020, 320:126530
  • Korean J of Crop Science2019, 452-458
  • Molecules.2019, 24(16):E3003
  • J Agric Food Chem.2021, 69(46):14037-14047.
  • Horticulturae2021, 7(1),5.
  • Genes (Basel).2021, 12(7):1024.
  • Planta Med.2018, 84(6-07):465-474
  • Food and Fermentation Industries2018, 44(371)
  • Phytother Res.2022, ptr.7573.
  • Psychopharmacology (Berl).2020, 10.1007
  • Food Chem.2017, 221:1135-1144
  • Plos One.2020, 10.1371
  • Evid Based Complement Alternat Med.2021, 2021:8850744.
  • Appl. Sci. 2021, 11(1),14.
  • Nutrients.2021, 13(8):2901.
  • Phytomedicine.2019, 57:95-104
  • Korean J. Medicinal Crop Sci.2022, 30(2):117-123.
  • Oncotarget.2017, 8(64):108006-108019
  • Comput Biol Chem.2019, 83:107096
  • Molecules.2021, 26(2):E255.
  • J Ethnopharmacol.2020, 254:112733.
  • Int J Mol Sci.2021, 22(12):6466.
  • ...
  • 生物活性
    Description: (2S,3S,4R,2′R)-2-(2′-hydroxytetracosanoylamino)octadecane-1,3,4-triol shows selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom at concentration of 100 ug/mL.
    Targets: Phospholipase (e.g. PLA)
    In vitro:
    Chinese Journal of Organic Chemistry, 2003, 23(8): 853-7.
    Chemical constituents of the fungus Leccinum extremiorientale.[Reference: WebLink]

    METHODS AND RESULTS:
    Thirteen chemical constituents were isolated from the fruiting bodies of basidiomyctes Leccinum extremiorientale, and their structures were elucidated by spectral and physical-chemical data as: ergosta-7,22-dien3β,5α ,6β-triol (1), ergosterol peroxide (2), ergosterol (3), ergosta-4,6,8(14),22-tetraen-3-one (4), ergosta-5,7-dien-3β-ol (5), palmitic acid (6), (2S,3S,4R,2′R )-2-(2'-Hydroxytetracosanoylamino)-octadecane-1,3,4-triol (7), cerebroside B (8), cerebroside D (9), uracil (10), inosine (11), adeosine (12) and D-allitol (13). The NMR data of compounds 8 and 9 were completely assigned by 2D-NMR techniques, including 1H- 1H COSY, HMBC and HMQC.
    CONCLUSIONS:
    Compounds 2, 7 and 8 at concentration of 100 μg/mL showed selectively inhibitory activity against phospholipase A 2 (PLA2) secreted from Crotalus adamenteus venom, but inactive against PLA2 of bee venom (Apis mellifcra). In addition, the methanol-chloroform soluble extract of this fungus also showed 67% antifeedant rate against Leucaninia separata and caused 55% mortality against Plutella xylostella after three-day application.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.4618 mL 7.3089 mL 14.6177 mL 29.2355 mL 36.5444 mL
    5 mM 0.2924 mL 1.4618 mL 2.9235 mL 5.8471 mL 7.3089 mL
    10 mM 0.1462 mL 0.7309 mL 1.4618 mL 2.9235 mL 3.6544 mL
    50 mM 0.0292 mL 0.1462 mL 0.2924 mL 0.5847 mL 0.7309 mL
    100 mM 0.0146 mL 0.0731 mL 0.1462 mL 0.2924 mL 0.3654 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    三七草酰胺II; Gynuramide II CFN98367 295803-03-1 C42H83NO5 = 682.1 5mg QQ客服:215959384
    (2R)-2-(乙酰氧基)-N-[(1S,2S,3R)-2,3-双(乙酰氧基)-1-[(乙酰氧基)甲基]十七烷基]二十四碳酰胺; 2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate CFN98439 340702-68-3 C50H93NO9 = 852.3 5mg QQ客服:215959384
    (2S,3S,4R,2'R)-2-(2'-羟基二十四碳酰氨基)十八烷-1,3,4-三醇; 2-(2'-Hydroxytetracosanoylamino)-octadecane-1,3,4-triol CFN99649 154801-30-6 C42H85NO5 = 684.1 5mg QQ客服:2056216494
    大豆脑苷I; Soyacerebroside I CFN99242 114297-20-0 C40H75NO9 = 714.0 5mg QQ客服:2056216494
    大豆脑苷II; Soyacerebroside II CFN99250 115074-93-6 C40H75NO9 = 714.0 5mg QQ客服:3257982914
    Momor-脑苷脂I; Momor-cerebroside I CFN97031 606125-07-9 C48H93NO10 = 844.3 5mg QQ客服:2159513211
    脑苷脂B; Cerebroside B CFN97455 88642-46-0 C41H77NO9 = 728.1 5mg QQ客服:215959384

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