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  • 根皮素-3',5'-二-C-β-葡萄糖苷

    Phloretin 3',5'-Di-C-glucoside

    根皮素-3',5'-二-C-β-葡萄糖苷
    产品编号 CFN95306
    CAS编号 357401-40-2
    分子式 = 分子量 C27H34O15 = 598.2
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The heartwoods of Nothofagus fusca
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    根皮素-3',5'-二-C-β-葡萄糖苷 CFN95306 357401-40-2 1mg QQ客服:1413575084
    根皮素-3',5'-二-C-β-葡萄糖苷 CFN95306 357401-40-2 5mg QQ客服:1413575084
    根皮素-3',5'-二-C-β-葡萄糖苷 CFN95306 357401-40-2 10mg QQ客服:1413575084
    根皮素-3',5'-二-C-β-葡萄糖苷 CFN95306 357401-40-2 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Copenhagen University (Denmark)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • Complutense University of Madrid (Spain)
  • University Medical Center Mainz (Germany)
  • Kyung Hee University (Korea)
  • Indian Institute of Science (India)
  • Ain Shams University (Egypt)
  • Research Unit Molecular Epigenetics (MEG) (Germany)
  • Tokyo Woman's Christian University (Japan)
  • Seoul National University of Science and Technology (Korea)
  • Chinese University of Hong Kong (China)
  • University of Vienna (Austria)
  • Medical University of Gdansk (Poland)
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Agric Food Chem.2021, 69(11):3496-3510.
  • Korean Journal of Pharmacognosy2014, 113-120
  • Aging (Albany NY).2021, 13(19):22867-22882.
  • Emirates Journal of Food and Agriculture.2022, 34(6): 528-536.
  • Tissue Cell.2022, 75:101728.
  • Int J Mol Sci.2021, 22(19):10220.
  • Molecules.2022, 27(7):2093.
  • J Chromatogr A.2022, 1685:463640.
  • J Pain Res.2022, 15:3469-3478.
  • Evid Based Complement Alternat Med.2021, 2021:5585692.
  • J Nat Prod.2022, 85(5):1351-1362.
  • Evid Based Complement Alternat Med.2022, 2022:3483511
  • J Sep Sci.2021, 44(22):4064-4081.
  • Inflammation.2021, doi: 10.1007
  • Universidade Estadual Paulista2017, 11449
  • Int J Mol Sci.2023, 24(3):2102.
  • Br J Pharmacol.2018, 175(6):902-923
  • Plant Growth Regulation2020, 90(2):383-392
  • Cell Metab.2020, S1550-4131(20)30002-4
  • Nutrients.2021, 13(8):2901.
  • Applied Biological Chemistry2022, 65(77).
  • Food Sci Nutr.2019, 8(1):246-256
  • Journal of Ginseng Research2019, 10.1016
  • ...
  • 生物活性
    Description: Phloretin 3',5'-Di-C-glucoside is able to inhibit growth of Gram positive bacteria.
    In vitro:
    Food Chem . 2014 Oct 1;160:292-7.
    Biochemical and antimicrobial activity of phloretin and its glycosilated derivatives present in apple and kumquat[Pubmed: 24799241]
    Phloretin and its glycosylated derivatives (phlorizin and phloretin 3',5'-di-C-glucoside) are dihydrochalcones that have many interesting biological properties. The results obtained showed that the dihydrochalcones are able to inhibit growth of Gram positive bacteria, in particular Staphylococcus aureus ATCC 6538, Listeria monocytogenes ATCC 13932 and methicillin-resistant S. aureus clinical strains. Moreover, phloretin is active also against the Gram negative bacteria Salmonella typhimurium ATCC 13311. The determination of the enzymatic activity of key metabolic enzymes allowed us to shed some light on the biochemical mechanism of aglycon cell growth inhibition, showing as it remarkably influences the energetic metabolism of S. aureus. In addition, structure/activity determinations highlighted that the presence of a glycosyl moiety bound to the chalcone structure dramatically decreases the antimicrobial activity of phloretin.
    Molecules 2012, 17(12), 14602-14624;
    Food Ingredient Extracts of Cyclopia subternata (Honeybush): Variation in Phenolic Composition and Antioxidant Capacity[Reference: WebLink]
    Cyclopia subternata plants are traditionally used for the production of the South African herbal tea, honeybush, and recently as aqueous extracts for the food industry. A C. subternata aqueous extract and mangiferin (a major constituent) are known to have anti-diabetic properties. Variation in phenolic composition and antioxidant capacity is expected due to cultivation largely from seedlings, having implications for extract standardization and quality control. Aqueous extracts from 64 seedlings of the same age, cultivated under the same environmental conditions, were analyzed for individual compound content, total polyphenol (TP) content and total antioxidant capacity (TAC) in a number of assays. An HPLC method was developed and validated to allow quantification of xanthones (mangiferin, isomangiferin), flavanones (hesperidin, eriocitrin), a flavone (scolymoside), a benzophenone (iriflophenone-3-C-β-glucoside) and dihydrochalcones (phloretin-3',5'-di-C-β-glucoside, 3-hydroxyphloretin-3',5'-di-C-hexoside). Additional compounds were tentatively identified using mass spectrometric detection, with the presence of the 3-hydroxyphloretin-glycoside, an iriflophenone-di-O,C-hexoside, an eriodictyol-di-C-hexoside and vicenin-2 being demonstrated for the first time. Variability of the individual phenolic compound contents was generally higher than that of the TP content and TAC values. Among the phenolic compounds, scolymoside, hesperidin and iriflophenone-3-C-β-glucoside contents were the most variable. A combination of the measured parameters could be useful in product standardization by providing a basis for specifying minimum levels.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6717 mL 8.3584 mL 16.7168 mL 33.4336 mL 41.792 mL
    5 mM 0.3343 mL 1.6717 mL 3.3434 mL 6.6867 mL 8.3584 mL
    10 mM 0.1672 mL 0.8358 mL 1.6717 mL 3.3434 mL 4.1792 mL
    50 mM 0.0334 mL 0.1672 mL 0.3343 mL 0.6687 mL 0.8358 mL
    100 mM 0.0167 mL 0.0836 mL 0.1672 mL 0.3343 mL 0.4179 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    柚皮苷二氢查尔酮; Naringin dihydrochalcone CFN90437 18916-17-1 C27H34O14 = 582.55 20mg QQ客服:1457312923
    3-羟基根皮苷; Sieboldin CFN70294 18777-73-6 C21H24O11 = 452.4 5mg QQ客服:2056216494
    新橙皮苷二氢查尔酮; Neosperidin dihydrochalcone CFN98168 20702-77-6 C28H36O15 = 612.58 20mg QQ客服:2056216494
    橙皮苷甲基查尔酮; Hesperidin methylchalcone CFN80405 24292-52-2 C29H36O15 = 624.59 20mg QQ客服:3257982914
    地奥司明杂质5; Diosmin Impurity 5 CFN95311 122087-66-5 C30H38O15 = 638.6 10mg QQ客服:215959384
    二氢马里苷; Dihydromarein CFN90853 N/A C21H24O11 = 452.4 5mg QQ客服:3257982914
    马里苷; Marein CFN90851 535-96-6 C21H22O11 = 450.4 10mg QQ客服:215959384
    新异甘草苷; Neoisoliquiritin CFN90823 59122-93-9 C21H22O9 = 418.4 10mg QQ客服:3257982914
    异甘草苷; Isoliquiritin CFN99155 5041-81-6 C21H22O9 = 418.39 20mg QQ客服:215959384
    芹糖异甘草苷; Isoliquiritin apioside CFN90800 120926-46-7 C26H30O13 = 550.5 20mg QQ客服:2056216494

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