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  • 短葶山麦冬皂苷C

    Liriope muscari baily saponins C

    短葶山麦冬皂苷C
    产品编号 CFN90194
    CAS编号 87480-46-4
    分子式 = 分子量 C44H70O14 = 855.02
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Steroids
    植物来源 The roots of Liriope muscari
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    短葶山麦冬皂苷C CFN90194 87480-46-4 10mg QQ客服:3257982914
    短葶山麦冬皂苷C CFN90194 87480-46-4 20mg QQ客服:3257982914
    短葶山麦冬皂苷C CFN90194 87480-46-4 50mg QQ客服:3257982914
    短葶山麦冬皂苷C CFN90194 87480-46-4 100mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
  • University of British Columbia (Canada)
  • Florida A&M University (USA)
  • Universidade Federal de Pernambuco (UFPE) (Brazil)
  • National Hellenic Research Foundation (Greece)
  • University of Perugia (Italy)
  • VIT University (India)
  • University of Limpopo (South Africa)
  • University of Bordeaux (France)
  • Yale University (USA)
  • University of Canterbury (New Zealand)
  • Shanghai Institute of Biochemistry and Cell Biology (China)
  • Periyar University (India)
  • Cancer Research Initatives Foundation(CARIF) (Malaysia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Cell Physiol.2021, 236(3):1950-1966.
  • J Microbiol Biotechnol.2022, 32(2):141-148.
  • Phytother Res.2018, 32(12):2551-2559
  • Molecules.2019, 24(19):E3417
  • The Journal of Korean Medicine2022, 43(3): 79-93.
  • Planta Med.2016, 82(13):1208-16
  • Exp Biol Med (Maywood).2019, 244(16):1463-1474
  • Int J Mol Sci.2022, 23(21):13112.
  • Front Plant Sci.2022, 13:982771.
  • J Ethnopharmacol.2017, 197:157-164
  • Plant Pathology2022, 13527
  • Front Plant Sci.2021, 12: 648426.
  • Phytomedicine.2017, 24:77-86
  • Front Immunol.2023, 14:1240800.
  • Molecules.2021, 26(16):4722.
  • J Agric Food Chem.2016, 64(35):6783-90
  • Cell Death Differ.2021, 1-8.
  • Journal of Third Military Medical University2018, 40(12):1073-1078
  • J Agric Food Chem.2021, 69(14):4210-4222.
  • J Pharmaceut Biomed2020, 178:112894
  • Chem Biol Interact.2018, 290:44-51
  • Front Microbiol.2021, 12:736780.
  • Front Nutr.2021, 8: 687851.
  • ...
  • 生物活性
    Description: Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of IL-6 and TF.
    Targets: IL Receptor
    In vivo:
    Indian J Pharmacol. 2013 May-Jun; 45(3): 283–285.
    Anti-thrombotic activity of DT-13, a saponin isolated from the root tuber of Liriope muscari.[Pubmed: 23833374]
    To investigate the anti-thrombotic activity of DT-13(Liriope muscari baily saponins C) in experimental animal models.
    METHODS AND RESULTS:
    The anti-thrombotic activity of DT-13 was evaluated by measuring the thrombus induced by inferior vena cava (IVC) ligation in mice and rats. The anti-thrombotic mechanism of DT-13 was investigated by assessing the mRNA expression levels of interleukin-6 (IL-6) and tissue factor (TF) in rat IVC tissue around thrombus. DT-13 markedly inhibited thrombosis induced by IVC ligation for 6 h in mice (2.0 and 4.0 mg/kg, p.o.) and for 18 h in rats (1.4 mg/kg, p.o.). Furthermore, DT-13 down-regulated the increased mRNA expression levels of IL-6 and TF in rats.
    CONCLUSIONS:
    DT-13 has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of IL-6 and TF.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.1696 mL 5.8478 mL 11.6956 mL 23.3913 mL 29.2391 mL
    5 mM 0.2339 mL 1.1696 mL 2.3391 mL 4.6783 mL 5.8478 mL
    10 mM 0.117 mL 0.5848 mL 1.1696 mL 2.3391 mL 2.9239 mL
    50 mM 0.0234 mL 0.117 mL 0.2339 mL 0.4678 mL 0.5848 mL
    100 mM 0.0117 mL 0.0585 mL 0.117 mL 0.2339 mL 0.2924 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    短葶山麦冬皂苷C; Liriope muscari baily saponins C CFN90194 87480-46-4 C44H70O14 = 855.02 20mg QQ客服:215959384
    麦冬皂苷D'; Ophiopogonin D' CFN90503 65604-80-0 C44H70O16 = 855.02 10mg QQ客服:3257982914
    纤细薯蓣皂苷; Gracillin CFN98537 19083-00-2 C45H72O17 = 885.04 20mg QQ客服:1413575084
    重楼皂苷D; Polyphyllin D CFN90255 50773-41-6 C44H70O16 = 855.02 20mg QQ客服:1457312923
    薯蓣皂甙;薯蓣皂苷; Dioscin CFN99516 19057-60-4 C45H72O16 = 869.05 20mg QQ客服:215959384
    重楼皂苷II; Polyphyllin II CFN99953 76296-72-5 C44H70O16 = 855.02 5mg QQ客服:215959384
    重楼皂苷E; Polyphyllin E CFN90446 76296-73-6 C51H82O20 = 1015.18 5mg QQ客服:215959384
    重楼皂苷F; Polyphyllin F CFN90447 76296-74-7 C51H82O20 = 1015.18 5mg QQ客服:1413575084

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