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  • 7-木糖基-紫杉醇

    7-Xylosyltaxol

    7-木糖基-紫杉醇
    产品编号 CFN98515
    CAS编号 90332-66-4
    分子式 = 分子量 C52H59NO18 = 986.0
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Diterpenoids
    植物来源 The barks of Taxus baccata
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    7-木糖基-紫杉醇 CFN98515 90332-66-4 1mg QQ客服:215959384
    7-木糖基-紫杉醇 CFN98515 90332-66-4 5mg QQ客服:215959384
    7-木糖基-紫杉醇 CFN98515 90332-66-4 10mg QQ客服:215959384
    7-木糖基-紫杉醇 CFN98515 90332-66-4 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Eastern Finland (Finland)
  • Universidade Federal de Pernambuco (UFPE) (Brazil)
  • Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)
  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
  • Calcutta University (India)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • University of Bonn (Germany)
  • Universidade do Porto (Portugal)
  • MTT Agrifood Research Finland (Finland)
  • Universidade de Franca (Brazil)
  • Subang Jaya Medical Centre (Malaysia)
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  • University of Vigo (Spain)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Foods.2023, 12(12):2412.
  • National Academy Science Letters2023, s40009.
  • Curr Issues Mol Biol.2022, 44(5):2300-2308.
  • Int J Mol Sci.2021, 22(17):9400.
  • J Pharm Biomed Anal.2021, 196:113931.
  • Nutrients.2022, 14(23):4997.
  • Biomed Pharmacother.2022, 156:113929.
  • Korean J. Food Preserv. 2021, 28(6):846-856.
  • Journal of Functional Foods2021, 84:104581
  • LWT2020, 124:109163
  • Nutrients.2022, 14(19):4170.
  • J Ethnopharmacol.2016, 192:370-381
  • iScience.2023, 26(9):107602.
  • Phytomedicine.2022, 100:154036.
  • J Pharm Anal.2016, 6(6):363-373
  • J Ethnopharmacol.2019, 228:132-141
  • J Sep Sci.2020, 43(22):4148-4161.
  • Aging (Albany NY).2021, 13(19):22867-22882.
  • Nat Prod Commun.2014, 9(5):679-82
  • Mol Med Rep.2022, 26(4):299.
  • Biochem Pharmacol.2020, 178:114083
  • J Inflamm Res.2022, 15:5347-5359.
  • J Cell Mol Med.2023, 27(10):1423-1435.
  • ...
  • 生物活性
    Description: 7-xylosyltaxol is a taxol (Paclitaxel) derivative, has antineoplastic activity.
    In vitro:
    J Nat Med. 2013 Jul;67(3):512-8.
    Development of an indirect competitive enzyme-linked immunosorbent assay (icELISA) using highly specific monoclonal antibody against paclitaxel.[Pubmed: 23007175]
    Paclitaxel, the major active component of the yew tree, is used as an important anti-cancer agent.
    METHODS AND RESULTS:
    To obtain the monoclonal antibody (MAb) against paclitaxel for paclitaxel determination using immunoassay, 7-xylosyltaxol was conjugated to the carrier protein bovine serum albumin (BSA) to construct the immunogen, and the ratio of hapten in XylTax-BSA conjugate was determined by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. After immunization of mice with this conjugate, hybridomas secreting MAbs against paclitaxel were obtained by fusing the splenocytes with the mouse myeloma cell line SP2/0. After hybridoma screening, the anti-paclitaxel MAb 3A3 was obtained, which showed a relatively high specificity to paclitaxel (cross-reactivities against other naturally occurred taxanes: 7-xylosyltaxol, 31.8%; cephalomannine, 6.17%; baccatin III, 10-deacetyl-baccatin III, 1-hydroxybaccatin I, 13-acetyl-9-dihydrobaccatin III and 1-acetoxyl-5-deacetyl-baccatin I, <0.11%). Using the MAb 3A3, we established an indirect competitive enzyme-linked immunosorbent assay (icELISA) for paclitaxel determination with a detection range of 0.098-312.5 μg ml(-1). Determination of paclitaxel contents in various yew tree samples with this icELISA resulted in recovery rates ranging from 92 to 94.8%, and intra- and inter-assay variations of 3.6 and 4.7%, respectively.
    CONCLUSIONS:
    This icELISA provides a valuable method of paclitaxel determination for various purposes.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.0142 mL 5.071 mL 10.142 mL 20.284 mL 25.355 mL
    5 mM 0.2028 mL 1.0142 mL 2.0284 mL 4.0568 mL 5.071 mL
    10 mM 0.1014 mL 0.5071 mL 1.0142 mL 2.0284 mL 2.5355 mL
    50 mM 0.0203 mL 0.1014 mL 0.2028 mL 0.4057 mL 0.5071 mL
    100 mM 0.0101 mL 0.0507 mL 0.1014 mL 0.2028 mL 0.2535 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    三尖杉宁碱; Cephalomannine CFN98518 71610-00-9 C45H53NO14 = 831.91 20mg QQ客服:3257982914
    10-去乙酰紫杉醇; Deacetyltaxol CFN90687 78432-77-6 C45H49NO13 = 811.87 20mg QQ客服:3257982914
    7-表紫杉醇; 7-Epitaxol CFN90371 105454-04-4 C47H51NO14 = 853.91 20mg QQ客服:1413575084
    紫杉醇; Paclitaxel CFN97759 33069-62-4 C47H51NO14 = 853.92 20mg QQ客服:2159513211
    7-木糖基-紫杉醇; 7-Xylosyltaxol CFN98515 90332-66-4 C52H59NO18 = 986.0 5mg QQ客服:2159513211
    7-木糖甙-10-脱乙酰基紫杉醇; 10-Deacetyl-7-xylosyl paclitaxel CFN90837 90332-63-1 C50H57NO17 = 944.0 20mg QQ客服:1413575084
    7-表-10-去乙酰紫杉醇; 7-Epi-10-deacetyltaxol CFN89397 78454-17-8 C45H49NO13 = 811.86 20mg QQ客服:2159513211
    7-Epi-10-deacetylcephalomannine ; 7-Epi-10-deacetylcephalomannine CFN89395 78479-12-6 C43H51NO13 = 789.86 5mg QQ客服:1457312923
    10-去乙酰三尖杉宁碱; 10-Deacetylcephalomannine CFN95519 76429-85-1 C43H51NO13 = 789.9 10mg QQ客服:2159513211
    7-木糖基-10-去乙酰基紫杉醇 B; 7-Xylosyl-10-deacetyltaxol B CFN89389 90332-64-2 C48H59NO17 = 921.97 20mg QQ客服:215959384

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