1,1,3,3-四乙氧基丙烷

Tetraethoxypropane

	产品编号	CFN90064
	CAS编号	122-31-6
	分子式 = 分子量	C₁₁H₂₄O₄ = 220.31
	产品纯度	>=98%
	物理属性	Liquid
	化合物类型	Miscellaneous
	植物来源
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
1,1,3,3-四乙氧基丙烷	CFN90064	122-31-6	10mg	QQ客服：215959384
1,1,3,3-四乙氧基丙烷	CFN90064	122-31-6	20mg	QQ客服：215959384
1,1,3,3-四乙氧基丙烷	CFN90064	122-31-6	50mg	QQ客服：215959384
1,1,3,3-四乙氧基丙烷	CFN90064	122-31-6	100mg	QQ客服：215959384

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Technical University of Denmark (Denmark)

Martin Luther University of Halle-Wittenberg (Germany)

Istanbul University (Turkey)

Centrum Menselijke Erfelijkheid (Belgium)

Sanford Burnham Prebys Medical Discovery Institute (USA)

Max Rubner-Institut (MRI) (Germany)

University of Hawaii Cancer Center (USA)

Universidad de La Salle (Mexico)

Universidade Federal de Pernambuco (UFPE) (Brazil)

Medizinische Universit?t Wien (Austria)

Kyushu University (Japan)

University of Madras (India)

National Hellenic Research Foundation (Greece)

Monash University Malaysia (Malaysia)

More...

Description:

1,1,3,3-Tetraethoxypropane,the precursor of the ubiquitous natural compound malondialdehyde. Tetraethoxypropane as the standard in the thiobarbituric acid (TBA) assay.

In vitro:

J Appl Toxicol. 2003 Sep-Oct;23(5):363-9.

Effect of quercetin and genistein on copper- and iron-induced lipid peroxidation in methyl linolenate.[Pubmed: 12975775]

The single and combined effects of two abundant flavonoids, namely quercetin and genistein, were investigated according to their ability to inhibit the oxidation of methyl linolenate via Fenton's pathway.
METHODS AND RESULTS:
Antioxidative activity was determined by oxidizing methyl linolenate suspended in a buffer solution with either Fe2+ (50 microM) or Cu2+ (50 microM) and hydrogen peroxide (0.01 mM) without or with a flavonoid sample (10 or 20 microM). Lipid peroxidation products were measured by the thiobarbituric acid (TBA) assay and the amounts of thiobarbituric acid-reactive substances (TBARS) were calculated from a calibration curve using 1,1,3,3-tetraethoxypropane as the standard. Both quercetin and genistein at the 10 or 20 microM level decreased lipid peroxidation significantly compared with their respective controls. Of the two flavonoids tested, quercetin had a more marked effect on inhibiting lipid peroxides. Peroxidation products for the control samples were higher for the Fe2+-treated samples compared with the Cu2+ samples. Combination of both flavonoids at the same dose levels continued to decrease lipid peroxidation, the effect being the same for both metal ions.
CONCLUSIONS:
The data suggest that the combined flavonoids offered better protection than the single treatments and this may be attributed to the better radical scavenging or increased chelating capabilities of the combined over the single treatments. The differences in peroxide levels for the single treatment of quercetin compared with the genistein-treated samples may reflect the structural differences between these compounds in combating oxidative stress.

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.5391 mL	22.6953 mL	45.3906 mL	90.7812 mL	113.4765 mL
5 mM	0.9078 mL	4.5391 mL	9.0781 mL	18.1562 mL	22.6953 mL
10 mM	0.4539 mL	2.2695 mL	4.5391 mL	9.0781 mL	11.3476 mL
50 mM	0.0908 mL	0.4539 mL	0.9078 mL	1.8156 mL	2.2695 mL
100 mM	0.0454 mL	0.227 mL	0.4539 mL	0.9078 mL	1.1348 mL