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  • 砂生槐异黄酮 A

    Sophoraisoflavone A

    砂生槐异黄酮 A
    产品编号 CFN96513
    CAS编号 117204-81-6
    分子式 = 分子量 C20H16O6 = 352.34
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The root exudates of white lupin.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    砂生槐异黄酮 A CFN96513 117204-81-6 1mg QQ客服:3257982914
    砂生槐异黄酮 A CFN96513 117204-81-6 5mg QQ客服:3257982914
    砂生槐异黄酮 A CFN96513 117204-81-6 10mg QQ客服:3257982914
    砂生槐异黄酮 A CFN96513 117204-81-6 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
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    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universidad Veracuzana (Mexico)
  • University of Wuerzburg (Germany)
  • Rio de Janeiro State University (Brazil)
  • Shanghai Institute of Organic Chemistry (China)
  • Griffith University (Australia)
  • Wageningen University (Netherlands)
  • University of Brasilia (Brazil)
  • University of Helsinki (Finland)
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  • Chiang Mai University (Thailand)
  • Sanford Burnham Medical Research Institute (USA)
  • Universiti Malaysia Pahang (Malaysia)
  • University of Parma (Italy)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Nutrients.2020, 12(12):3607.
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  • Anal Chim Acta.2018, 1039:162-171
  • J. Soc. Cosmet. Sci. Korea2021, 47(1):57-63
  • Biochem Biophys Res Commun.2017, 482(4):1095-1101
  • Applied Biological Chemistry2020, 63:37.
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  • Sci Rep.2021, 11(1):21038.
  • Cells.2022, 11(8), 1311.
  • Biosci Biotechnol Biochem.2021, 85(10):2153-2160.
  • Jour. of Stored Pro & Postharvest Res.2016, 7(3):32-36
  • Oncol Lett.2020, 20(4):122.
  • Biomed Chromatogr.2019, 8:e4774
  • Biomed Pharmacother.2021, 144:112300.
  • University of Limpopo2016, 1777
  • Antimicrob Agents Chemother.2020, AAC.01921-20.
  • Biomedicine & Pharmacotherapy2020, 125:109950
  • Front Plant Sci.2022, 13:982771.
  • PLoS One.2017, 12(8):e0181191
  • ...
  • 生物活性
    Description: Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tube growth at 1.25 ug/disc. Sophoraisoflavone A shows inhibitory effects on copper-induced protein oxidative modification of mice brain homogenate in vitro.
    Targets: Antifection | MRP
    In vitro:
    Phytochemistry. 2010 Nov;71(16):1865-71.
    Lupin pyranoisoflavones inhibiting hyphal development in arbuscular mycorrhizal fungi.[Pubmed: 20813384]

    METHODS AND RESULTS:
    White lupin (Lupinus albus L.), a non-host plant for arbuscular mycorrhizal (AM) fungi in the typically mycotrophic family Fabaceae, has been investigated for root metabolites that inhibit hyphal development in AM fungi. Four known pyranoisoflavones, licoisoflavone B (1), sophoraisoflavone A (2), alpinumisoflavone (3) and 3'-hydroxy-4'-O-methylalpinumisoflavone (4), together with three previously unknown pyranoisoflavones, lupindipyranoisoflavone A (5), 10'-hydroxylicoisoflavone B (6) and 10'-hydroxysophoraisoflavone A (7) were isolated from the root exudates of white lupin as an inhibitor of germ tube growth in the AM fungus Gigaspora margarita.
    CONCLUSIONS:
    Pyranoisoflavones 1, 2 and 3 strongly inhibited germ tube growth at 0.63, 1.25 and 0.63 μg/disc, respectively. The remaining compounds 4-7 were either moderate or weak inhibitors that inhibited germ tube growth at concentrations higher than 10 μg/disc. Licoisoflavone B (1) and sophoraisoflavone A (2) completely inhibited hyphal branching induced by a lupin strigolactone, orobanchyl acetate, in G. margarita at 0.16 and 0.63 μg/disc, respectively.
    Biol Trace Elem Res. 2001 Aug;81(2):169-75.
    Inhibitory effects of licoisoflavones A and B and sophoraisoflavone A of Sophra mooracroftiana Beth ex Baker on copper-ion-induced protein oxidative modification of mice brain homogenate, in vitro.[Pubmed: 11554397 ]

    METHODS AND RESULTS:
    We present the results of an in vitro investigation of the inhibitory effects of licoisoflavones A and B and sophoraisoflavone A isolated from Sophra mooracroftiana BETH ex BAKER on copper-induced protein oxidative modification of mice brain homogenate in vitro. Although inhibitory effect of sophoraisoflavone A was stronger than those of licoisoflavones A and B, genistein as a related isoflavone, and mannitol as a hydroxy radical scavenger, inhibitory effects of licoisoflavones A and B were weaker than those of genistein and mannitol.
    CONCLUSIONS:
    These results demonstrated that the difference of inhibitory effects are dependent on the relation between chemical structures of these isoflavones, such as hydroxy group or benzopyran, and oxidative stress.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8382 mL 14.1908 mL 28.3817 mL 56.7634 mL 70.9542 mL
    5 mM 0.5676 mL 2.8382 mL 5.6763 mL 11.3527 mL 14.1908 mL
    10 mM 0.2838 mL 1.4191 mL 2.8382 mL 5.6763 mL 7.0954 mL
    50 mM 0.0568 mL 0.2838 mL 0.5676 mL 1.1353 mL 1.4191 mL
    100 mM 0.0284 mL 0.1419 mL 0.2838 mL 0.5676 mL 0.7095 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    甘草异黄烷酮; Licoisoflavanone CFN96544 66067-26-3 C20H18O6 = 354.36 5mg QQ客服:1413575084
    粗毛甘草素F; Glyasperin F CFN94013 145382-61-2 C20H18O6 = 354.35 5mg QQ客服:1413575084
    二氢甘草异黄酮; Dihydrolicoisoflavone CFN95073 164163-92-2 C20H20O6 = 356.4 5mg QQ客服:3257982914
    5,7,2',4'-Tetrahydroxy-8,3'-di(γ,γ-dimethylallyl)-isoflavanone; 5,7,2',4'-Tetrahydroxy-8,3'-di(gamma,gamma-dimethylallyl)-isoflavanone CFN95084 141846-47-1 C25H28O6 = 424.5 5mg QQ客服:2159513211
    2',4'-二羟基-7-甲氧基异黄酮; 5-Deoxycajanin CFN97240 7622-53-9 C16H12O5 = 284.3 5mg QQ客服:215959384
    2',4',5,7-四羟基异黄烷酮; Dalbergioidin CFN97931 30368-42-4 C15H12O6 = 288.3 5mg QQ客服:1413575084
    2'-羟基染料木素; 2'-Hydroxygenistein CFN99257 1156-78-1 C15H10O6 = 286.2 5mg QQ客服:2056216494
    Lupinalbin A; Lupinalbin A CFN80045 98094-87-2 C15H8O6 = 284.03 5mg QQ客服:215959384
    2-羟基异樱黄素; Barpisoflavone A CFN97861 101691-27-4 C16H12O6 = 300.27 5mg QQ客服:2159513211
    木豆异黄酮; 2',4',5-三羟基-7-甲氧基异黄酮; Cajanin CFN98419 32884-36-9 C16H12O6 = 300.3 5mg QQ客服:215959384

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