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  • 西伯利亚远志呫吨酮B

    Sibiricaxanthone B

    西伯利亚远志呫吨酮B
    产品编号 CFN90644
    CAS编号 241125-81-5
    分子式 = 分子量 C24H26O14 = 538.45
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Xanthones
    植物来源 The roots of Polygala tenuifolia
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    西伯利亚远志呫吨酮B CFN90644 241125-81-5 10mg QQ客服:215959384
    西伯利亚远志呫吨酮B CFN90644 241125-81-5 20mg QQ客服:215959384
    西伯利亚远志呫吨酮B CFN90644 241125-81-5 50mg QQ客服:215959384
    西伯利亚远志呫吨酮B CFN90644 241125-81-5 100mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Regional Crop Research Institute (Korea)
  • Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)
  • Universidade do Porto (Portugal)
  • Lund University (Sweden)
  • Istanbul University (Turkey)
  • Subang Jaya Medical Centre (Malaysia)
  • Martin Luther University of Halle-Wittenberg (Germany)
  • National Chung Hsing University (Taiwan)
  • Funda??o Universitária de Desenvolvimento (Brazil)
  • Georgia Institute of Technology (USA)
  • Aveiro University (Portugal)
  • Kyung Hee University (Korea)
  • Universita' Degli Studi Di Cagliari (Italy)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Neurotoxicology.2022, 91:218-227.
  • Dent Mater J.2020, 39(4):690-695
  • Molecules.2022, 27(7):2116.
  • Academic J of Second Military Medical University2018, 39(11)
  • Institute of Food Science & Technology2021, 45(9).
  • Evid Based Complement Alternat Med.2021, 8855980.
  • Plants (Basel).2023, 12(22):3877.
  • Biol Pharm Bull.2020, 43(10):1534-1541.
  • Anal Bioanal Chem.2020, 412(12):3005-3015.
  • J Asian Nat Prod Res.2019, 5:1-17
  • Foods.2022, 11(6):882.
  • Plant Foods Hum Nutr.2021, 76(4):472-477.
  • Iranian Journal of Pharmaceutical Sciences2021, 17(2):25-36
  • Molecules.2016, 21(6)
  • Acta Edulis Fungi2020, 27(02):63-76.
  • LWT2020, 126:109313
  • Research Square2021, 10.21203.
  • Food Addit Contam Part A.2021, 38(12):1985-1994.
  • J Mol Recognit.2020, 33(2):e2819
  • J Biomed Sci.2020, 27(1):60.
  • Life (Basel).2021, 11(12):1399.
  • Exp Parasitol.2018, 194:67-78
  • ACS Synth Biol.2022, doi: 10.1021.
  • ...
  • 生物活性
    Description: Sibiricaxanthone B is a natural product from Polygala tenuifolia.
    In vivo:
    J Sep Sci. 2017 May;40(10):2131-2140.
    Ultra-fast liquid chromatography with tandem mass spectrometry determination of eight bioactive components of Kai-Xin-San in rat plasma and its application to a comparative pharmacokinetic study in normal and Alzheimer's disease rats.[Pubmed: 28342292]
    A method of ultra-fast liquid chromatography with tandem mass spectrometry was developed and validated for the simultaneous quantitation of eight bioactive components, including polygalaxanthone III, Sibiricaxanthone B, tenuifolin, sibiricose A5, sibiricose A6, tenuifoliside A, ginsenoside Re and ginsenoside Rb1 in rat plasma after oral administration of Kai-Xin-San.
    METHODS AND RESULTS:
    The plasma samples were extracted by liquid-liquid extraction using digoxin as an internal standard. Chromatographic separation was performed on a Venusil MP C18 column (100 mm × 2.1 mm, 3 μm) with methanol and 0.05% acetic acid in water as mobile phase. The tandem mass spectrometric detection was performed in the multiple reaction monitoring with turbo ion spray source in the negative ionization. Validation parameters were within acceptable ranges. The established method has been successfully applied to compare the pharmacokinetic profiles of the analytes between normal and Alzheimer's disease rats.
    CONCLUSIONS:
    The results indicated that there were significant differences in pharmacokinetic parameters of some components between two groups, which may be due to the mechanisms of Alzheimer's disease and pharmacological effects of the analytes. The pharmacokinetic research in the pathological state might provide more useful information to guide the clinical usage of herbal medicine.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8572 mL 9.2859 mL 18.5718 mL 37.1437 mL 46.4296 mL
    5 mM 0.3714 mL 1.8572 mL 3.7144 mL 7.4287 mL 9.2859 mL
    10 mM 0.1857 mL 0.9286 mL 1.8572 mL 3.7144 mL 4.643 mL
    50 mM 0.0371 mL 0.1857 mL 0.3714 mL 0.7429 mL 0.9286 mL
    100 mM 0.0186 mL 0.0929 mL 0.1857 mL 0.3714 mL 0.4643 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    当药醇苷; Swertianolin CFN90618 23445-00-3 C20H20O11 = 436.37 10mg QQ客服:215959384
    4-β-D-葡萄糖基-1,3,7-三羟基呫吨酮; Lancerin CFN90666 81991-99-3 C19H18O10 = 406.34 5mg QQ客服:1457312923
    异芒果苷; 异杞果素; Isomangiferin CFN90385 24699-16-9 C19H18O11 = 422.34 20mg QQ客服:215959384
    新芒果苷; Neomangiferin CFN98122 64809-67-2 C25H28O16 = 584.48 20mg QQ客服:1457312923
    芒果苷; 芒果甙; Mangiferin CFN98719 4773-96-0 C19H18O11 = 422.3 20mg QQ客服:215959384
    高芒果苷; Homomangiferin CFN80148 21794-66-1 C20H20O11 = 436.36 5mg QQ客服:1413575084
    7-O-甲基芒果素; 7-O-Methylmangiferin CFN90667 31002-12-7 C20H20O11 = 436.37 20mg QQ客服:215959384
    远志山酮III; Polygalaxanthone III CFN90208 162857-78-5 C25H28O15 = 568.39 20mg QQ客服:1413575084
    远志咕吨酮Ⅺ; Polygalaxanthone XI CFN89072 857859-82-6 C25H28O15 = 568.48 20mg QQ客服:3257982914
    西伯利亚远志呫吨酮B; Sibiricaxanthone B CFN90644 241125-81-5 C24H26O14 = 538.45 20mg QQ客服:3257982914

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