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  • 莱苞迪甙D; 莱苞迪苷D

    Rebaudioside D

    莱苞迪甙D; 莱苞迪苷D
    产品编号 CFN90257
    CAS编号 63279-13-0
    分子式 = 分子量 C50H80O28 = 1129.15
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Diterpenoids
    植物来源 The leaves of Stevia rebaudiana Bertoni.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    莱苞迪甙D; 莱苞迪苷D CFN90257 63279-13-0 10mg QQ客服:1413575084
    莱苞迪甙D; 莱苞迪苷D CFN90257 63279-13-0 20mg QQ客服:1413575084
    莱苞迪甙D; 莱苞迪苷D CFN90257 63279-13-0 50mg QQ客服:1413575084
    莱苞迪甙D; 莱苞迪苷D CFN90257 63279-13-0 100mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Minnesota (USA)
  • University of Queensland (Australia)
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  • Regional Crop Research Institute (Korea)
  • Celltrion Chemical Research Institute (Korea)
  • The Vancouver Prostate Centre (VPC) (Canada)
  • Stanford University (USA)
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  • Institute of Chinese Materia Medica (China)
  • Universidad de Antioquia (Colombia)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Molecules.2022, 27(21):7643.
  • Clin Transl Med.2021, 11(5):e392.
  • Journal of Food Quality2022, P:13, 6256310.
  • Biomed Pharmacother.2019, 111:262-269
  • Antioxidants (Basel).2022, 11(8):1471.
  • Pharmacol Rep.2022, 74(1):175-188.
  • Plant Physiol Biochem.2023, 201:107795.
  • Antioxidants (Basel).2021, 10(10):1620.
  • Microchemical Journal2022, 182: 107874.
  • Molecules2022, 27(14),4462
  • Research Square2021, 10.21203.
  • Scientific World Journal.2014, 2014:654193
  • BMC Plant Biol.2021, 21(1):60.
  • Appl Biochem Biotechnol.2020, 190(2):732-744
  • Neurotox Res.2022, 40(6):1937-1947.
  • J Sep Sci.2019, 42(21):3352-3362
  • J Biochem Mol Toxicol.2021, 35(5):e22731.
  • Phytochemistry.2021, 181:112539.
  • Mol Med Rep.2024, 29(2):26.
  • Acta Agriculturae Scandinavica2015, 381-383
  • BMC Complement Med Ther. 2020, 20(1):91.
  • Int J Mol Sci.2022, 23(11):6172.
  • Kor. J. Herbol.2019, 34(2):59-66
  • ...
  • 生物活性
    Description: Rebaudioside D is a potential sweetener. Rebaudioside D shows similar stability when exposed to simulate stomach and small intestine fluids, with susceptibility to hydrolytic degradation by enteric bacteria collected from the cecum.
    In vivo:
    Int J Toxicol. 2013 Jul;32(4):261-73.
    Metabolism and toxicity studies supporting the safety of rebaudioside D.[Pubmed: 23766392 ]
    Rebaudioside D (Reb D) is one of the several glycosides found in the leaves of Stevia rebaudiana (Bertoni) Bertoni (Compositae) which has been identified as a potential sweetener.
    METHODS AND RESULTS:
    The metabolism of Reb A and Rebaudioside D was evaluated in various in vitro matrices (simulated gastrointestinal fluids, rat liver microsomes, and rat cecal contents) and through analysis of plasma collected from rats in a dietary toxicity study. Reb A and Rebaudioside D showed similar stability when exposed to simulated stomach and small intestine fluids, with susceptibility to hydrolytic degradation by enteric bacteria collected from the cecum. Incubations with rat liver microsomes indicated that neither compound is expected to be metabolized by the liver enzymes. Plasma concentrations of Rebaudioside D, Reb A, and/or the final hydrolysis product of each compound, free/conjugated steviol, were consistent between animals administered either Rebaudioside D or Reb A in the diet. A repeated exposure dietary toxicity study was conducted to compare the safety of Rebaudioside D, when administered at target exposure levels of 500, 1000, and 2000 mg/kg body weight (bw)/d to Sprague-Dawley rats for 28 days, to that of Reb A administered at a target exposure level of 2000 mg/kg bw/d. There were no treatment-related effects on the general condition and behavior of the animals and no toxicologically relevant, treatment-related effects on hematology, serum chemistry, or urinalysis.
    CONCLUSIONS:
    Macroscopic and microscopic findings revealed no treatment-related effects on any organ evaluated. Results were comparable between the group administered 2000 mg/kg/d Rebaudioside D and the group administered 2000 mg/kg/d Reb A.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 0.8856 mL 4.4281 mL 8.8562 mL 17.7124 mL 22.1405 mL
    5 mM 0.1771 mL 0.8856 mL 1.7712 mL 3.5425 mL 4.4281 mL
    10 mM 0.0886 mL 0.4428 mL 0.8856 mL 1.7712 mL 2.2141 mL
    50 mM 0.0177 mL 0.0886 mL 0.1771 mL 0.3542 mL 0.4428 mL
    100 mM 0.0089 mL 0.0443 mL 0.0886 mL 0.1771 mL 0.2214 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    6'-O-Acetylpaniculoside II; 6'-O-Acetylpaniculoside II CFN97585 N/A C28H42O10 = 538.6 5mg QQ客服:215959384
    对映-9-羟基-15-氧代-16-贝壳杉烯-19-酸 beta-D-吡喃葡萄糖酯; ent-9-Hydroxy-15-oxo-16-kauren-19-oic acid beta-D-glucopyranosyl ester CFN97291 81263-96-9 C26H38O9 = 494.6 5mg QQ客服:215959384
    对映-6,9-二羟基-15-氧代-16-贝壳杉烯-19-酸beta-D-吡喃葡萄糖酯; ent-6,9-Dihydroxy-15-oxo-16-kauren-19-oic acid beta-D-glucopyranosyl ester CFN97293 81263-98-1 C26H38O10 = 510.6 5mg QQ客服:2056216494
    对映-6,11-二羟基-15-氧代-16-贝壳杉烯-19-酸beta-D-吡喃葡萄糖酯; ent-6,11-Dihydroxy-15-oxo-16-kauren-19-oic acid beta-D-glucopyranosyl ester CFN97292 81263-97-0 C26H38O10 = 510.6 5mg QQ客服:2056216494
    苍术苷二钾盐; Atractyloside potassium salt CFN98561 102130-43-8 C30H44K2O16S2 = 802.99 20mg QQ客服:1413575084
    羧基苍术苷;羟基苍术苷三钾盐; Carboxyatractyloside CFN90756 77228-71-8 C31H43K3O18S2 = 885.1 20mg QQ客服:2056216494
    甜菊糖苷; Steviolmonoside CFN91504 60129-60-4 C26H40O8 = 480.6 5mg QQ客服:215959384
    甜菊双糖苷; Steviolbioside CFN96485 41093-60-1 C32H50O13 = 642.73 20mg QQ客服:1413575084
    莱苞迪甙B; 莱苞迪苷B; Rebaudioside B CFN90470 58543-17-2 C38H60O18 = 804.87 20mg QQ客服:2159513211
    甜茶苷; Rubusoside CFN90167 64849-39-4 C32H50O13 = 642.73 20mg QQ客服:2159513211

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