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  • 圆齿火棘酸

    Pyracrenic acid

    圆齿火棘酸
    产品编号 CFN89164
    CAS编号 80832-44-6
    分子式 = 分子量 C39H54O6 = 618.85
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The aerial roots of Ficus microcarpa.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    圆齿火棘酸 CFN89164 80832-44-6 1mg QQ客服:2056216494
    圆齿火棘酸 CFN89164 80832-44-6 5mg QQ客服:2056216494
    圆齿火棘酸 CFN89164 80832-44-6 10mg QQ客服:2056216494
    圆齿火棘酸 CFN89164 80832-44-6 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Toronto (Canada)
  • University of Ioannina (Greece)
  • Chiang Mai University (Thailand)
  • Sanford Burnham Medical Research Institute (USA)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • Funda??o Universitária de Desenvolvimento (Brazil)
  • University of Vigo (Spain)
  • Complutense University of Madrid (Spain)
  • University of Toulouse (France)
  • Kitasato University (Japan)
  • Uniwersytet Gdański (Poland)
  • Cornell University (USA)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • The Australian National University (Australia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Journal of Ginseng Research2022, j.jgr.2022.09.005.
  • Korean J Dent Mater2020, 47(2):63-70.
  • Processes2021, 9(1), 153;
  • Talanta Open2023, 7:100227
  • The Journal of Korean Medicine2023, 44(4):26-40.
  • Regul Toxicol Pharmacol.2023, 142:105433.
  • Exp Biol Med (Maywood).2019, 244(16):1463-1474
  • Ind Crops Prod.2015, 67:185-191
  • Anat Rec (Hoboken).2021, 304(2):323-332.
  • J Clin Med.2022, 11(13):3662.
  • J Formos Med Assoc.2020, S0929-6646(20)30425-3
  • Kor. J. Herbol.2019, 34(2):59-66
  • Biomolecules.2020, 10(2):E184
  • Biomed Pharmacother.2019, 111:262-269
  • Food Control2022, 132:108434.
  • Biomed Sci Letters.2020, 26:319-326
  • Microchemical Journal2022, 182: 107874.
  • Environ Toxicol.2024, 39(3):1556-1566.
  • The Malaysian journal of pathology2019, 41(3):243-251
  • Bioorg Med Chem.2020, 28(12):115553.
  • Proc Biol Sci.2024, 291(2015):20232578.
  • The Journal of Supercritical Fluids2021, 176:105305.
  • Industrial Crops and Products2022, 188:115596.
  • ...
  • 生物活性
    Description: Pyracrenic acid is a potent elastase inhibitor with an IC50 value of 1.5 mg/mL. Pyracrenic acid shows DPPH radical scavenging activity. It also shows significant cytotoxic activities against human cancer cells COLO 205 and AGS.
    In vitro:
    Chem Biodivers. 2008 Apr;5(4):565-74.
    Cytotoxic triterpenoids from the root bark of Helicteres angustifolia.[Pubmed: 18421748 ]

    METHODS AND RESULTS:
    Three new triterpenoids, 3beta-acetoxy-27-[(E)-cinnamoyloxy]lup-20(29)-en-28-oic acid methyl ester (1), 3beta-acetoxy-27-[(4-hydroxybenzoyl)oxy]lup-20(29)-en-28-oic acid (2), and 3beta-acetoxy-27-[(4-hydroxybenzoyl)oxy]olean-12-en-28-oic acid methyl ester (3), together with nine known triterpenoids, 4-12, were isolated from the root bark of Helicteres angustifolia. The structures of these compounds were established on the basis of spectroscopic methods including 2D-NMR experiments. All twelve compounds were tested for their cytotoxic activities against human colorectal cancer (COLO 205), human hepatoma (Hep G2), and human gastric cancer (AGS) cell lines in vitro.
    CONCLUSIONS:
    Among them, compounds 2, 3, 3beta-O-[(E)-coumaroyl]betulinic acid (6), and Pyracrenic acid (7) showed significant cytotoxic activities against human cancer cells COLO 205 and AGS.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6159 mL 8.0795 mL 16.159 mL 32.318 mL 40.3975 mL
    5 mM 0.3232 mL 1.6159 mL 3.2318 mL 6.4636 mL 8.0795 mL
    10 mM 0.1616 mL 0.808 mL 1.6159 mL 3.2318 mL 4.0398 mL
    50 mM 0.0323 mL 0.1616 mL 0.3232 mL 0.6464 mL 0.808 mL
    100 mM 0.0162 mL 0.0808 mL 0.1616 mL 0.3232 mL 0.404 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    2alpha-羟基-3beta-乙酰白桦酸; 2alpha-hydroxy-3beta-acetyloxy-betulic acid CFN92092 1163728-89-9 C32H50O5 = 514.8 5mg QQ客服:215959384
    3,27-二羟基-20(29)-流明-28-酸甲酯; 3,27-Dihydroxy-20(29)-lupen-28-oic acid methyl ester CFN98305 263844-79-7 C31H50O4 = 486.7 5mg QQ客服:215959384
    3-乙酰氧基-27-羟基-20(29)-流明-28-羧酸甲酯; 3-Acetoxy-27-hydroxy-20(29)-lupen-28-oic acid methyl ester CFN98306 263844-80-0 C33H52O5 = 528.8 5mg QQ客服:2159513211
    23-羟基白桦酸; Anemosapogenin CFN90310 85999-40-2 C30H48O4 = 472.71 20mg QQ客服:1413575084
    白头翁皂苷A3; Anemoside A3 CFN90182 129724-84-1 C41H66O12 = 750.96 20mg QQ客服:215959384
    白头翁皂苷D; Pulsatilla saponin D CFN80453 848784-85-0 C47H76O17 = 913.10 5mg QQ客服:1413575084
    白头翁皂苷B; Pulchinenoside B CFN94819 135247-95-9 C53H86O22 = 1075.25 5mg QQ客服:1413575084
    白头翁皂苷B4; Anemoside B4 CFN99786 129741-57-7 C59H96O26 = 1221.38 20mg QQ客服:215959384
    白头翁皂苷E; Pulchinenoside E CFN80291 366814-43-9 C65H106O31 = 1383.534 5mg QQ客服:1457312923
    3alpha-Acetoxy-20-oxo-29-norlupane-23,28-dioic acid; 3alpha-Acetoxy-20-oxo-29-norlupane-23,28-dioic acid CFN96240 262272-76-4 C31H46O7 = 530.7 5mg QQ客服:215959384

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