Info: Read More
  • 中药标准品生产商,产品定制服务
  • Nudiposide

    Nudiposide

    Nudiposide
    产品编号 CFN89146
    CAS编号 62058-46-2
    分子式 = 分子量 C27H36O12 = 552.57
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Lignans
    植物来源 The stem barks of Saraca indica.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Nudiposide CFN89146 62058-46-2 1mg QQ客服:2159513211
    Nudiposide CFN89146 62058-46-2 5mg QQ客服:2159513211
    Nudiposide CFN89146 62058-46-2 10mg QQ客服:2159513211
    Nudiposide CFN89146 62058-46-2 20mg QQ客服:2159513211
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Kyung Hee University (Korea)
  • Ateneo de Manila University (Philippines)
  • National Research Council of Canada (Canada)
  • Calcutta University (India)
  • Leibniz Institute of Plant Biochemistry (Germany)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Chinese University of Hong Kong (China)
  • Universiti Malaysia Pahang (Malaysia)
  • Heidelberg University (Germany)
  • Wageningen University (Netherlands)
  • Weizmann Institute of Science (Israel)
  • Universidad de La Salle (Mexico)
  • MTT Agrifood Research Finland (Finland)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J AOAC Int.2021, 104(6):1634-1651.
  • Toxicol Rep.2021, 8:1131-1142.
  • Food Funct.2020, 11(2):1322-1333.
  • J Clin Med.2022, 11(13):3662.
  • J. Food Composition and Analysis2022, 114:104731
  • Journal of Physiology & Pathology in Korean Medicine.2018, 32(2): 106-112
  • Int J Mol Sci.2021, 22(21):11447.
  • Medicinal Chemistry Research 2021, 30:1117-1124.
  • Int Immunopharmacol.2022, 106:108603.
  • Biomolecules.2020, 10(6):925.
  • Oncotarget.2015, 6(31):30831-49
  • Pharmacognosy Magazine2018, 14(56):418-424
  • Oxid Med Cell Longev2019, 9056845:13
  • Molecules.2019, 24(24),4583
  • Phytomedicine.2021, 83:153483.
  • Plant Archives2020, 2(1),2929-2934
  • Nutrients.2021, 13(10):3414.
  • Int J Cosmet Sci.2019, 41(1):12-20
  • National University of Pharmacy2022, 1:73-76
  • Plants (Basel).2021, 10(7):1376.
  • ACS Nano.2018, 12(4):3385-3396
  • J Cell Biochem.2018, 119(2):2231-2239
  • Processes2021, 9(1), 153.
  • ...
  • 生物活性
    Description: Nudiposide has significant neuroprotective activities against glutamate-injured neurotoxicity in HT22 cells. It also exhibits protective effect against sepsis in a mouse model and can decrease the plasma levels of TNF-α, IL-10 and ALT activity.
    Targets: TNF-α | IL Receptor | ALT
    In vitro:
    Pharmacogn Mag. 2015 Oct;11(Suppl 2):S303-7.
    Neuroprotective compounds of Tilia amurensis.[Pubmed: 26664019]
    In this study, we isolated five compounds from T. amurensis and determined whether protected neuronal cells against glutamate-induced oxidative stress in HT22 cells.
    METHODS AND RESULTS:
    Compounds were isolated using chromatographic techniques including silica gel, Sephadex LH-20 open column and high performance liquid chromatography analysis, and evaluated neuroprotective effect in HT22 cells by 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay. RESULTS: β-D-fructofuranosyl α-D-glucopyranoside (1), (-)-epicatechin (2), Nudiposide (3), lyoniside (4), and scopoletin (5) were isolated by bioactivity-guided fractionation from the ethyl acetate fraction of T. amurensis. Among them, (-)-epicatechin, Nudiposide, lyoniside, and scopoletin had significant neuroprotective activities against glutamate-injured neurotoxicity in HT22 cells.
    CONCLUSIONS:
    These results demonstrated that compound two, three, four, and five have a pronounced protective effect against glutamate-induced neurotoxicity in HT22 cells.
    In vivo:
    Arch Pharm Res. 2011 Sep;34(9):1443-50.
    Protective constituents against sepsis in mice from the root barks of Ulmus davidiana var. japonica.[Pubmed: 21975805 ]

    METHODS AND RESULTS:
    In the course of isolating preventive agents against sepsis based on the in vivo assay model, eleven known compounds, (-)-catechin (1), catechin-7-O-β-apiofuranoside (2), catechin-7-O-α-Lrhamnopyranoside (3), catechin-3-O-α-L-rhamnopyranoside (4), catechin-7-O-β-D-glucopyranoside (5), butyl (+)-5'-methoxyisolariciresinol-9'-O-β-D-xylopyranoside (6), lyoniside (7), Nudiposide (8), α-nigerose (9), butyl α-D-fructofuranoside (10), and procyanidin B(3) (11) were isolated from the root barks of Ulmus davidiana var. japonica.
    CONCLUSIONS:
    Compounds 2, 6, and 8 significantly protected against sepsis in a mouse model with survival rates of mice exposed to 10 mg/kg of LPS/D-GalN ranged from 80%-100%. Among them, 8 exhibited the most potent protective effect and decreased the plasma levels of TNF-α, IL-10 and ALT activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8097 mL 9.0486 mL 18.0973 mL 36.1945 mL 45.2431 mL
    5 mM 0.3619 mL 1.8097 mL 3.6195 mL 7.2389 mL 9.0486 mL
    10 mM 0.181 mL 0.9049 mL 1.8097 mL 3.6195 mL 4.5243 mL
    50 mM 0.0362 mL 0.181 mL 0.3619 mL 0.7239 mL 0.9049 mL
    100 mM 0.0181 mL 0.0905 mL 0.181 mL 0.3619 mL 0.4524 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    异橄榄树脂素; Cycloolivil CFN96185 3064-05-9 C20H24O7 = 376.4 5mg QQ客服:2932563308
    异落叶松脂素; Isolariciresinol CFN98915 548-29-8 C20H24O6 = 360.4 5mg QQ客服:1148253675
    9,9'-O-Isopropyllidene-isolariciresinol; 9,9'-O-Isopropyllidene-isolariciresinol CFN98276 252333-71-4 C23H28O6 = 400.5 5mg QQ客服:2159513211
    异落叶松脂素 9'-beta-D-吡喃木糖苷; Schizandriside CFN96693 71222-06-5 C25H32O10 = 492.52 5mg QQ客服:2932563308
    (-)-异落叶松脂素-9'-O-beta-D-吡喃葡萄糖苷; (-)-Isolariciresinol 9'-O-glucoside CFN89431 143236-04-8 C26H34O11 = 522.54 5mg QQ客服:2159513211
    Vitexdoin A; Vitexdoin A CFN96194 1186021-77-1 C19H18O6 = 342.4 5mg QQ客服:1148253675
    7,8,9,9-四脱氢异落叶松树脂酚; 7,8,9,9-Tetradehydroisolariciresinol CFN99605 145918-59-8 C20H20O6 = 356.4 5mg QQ客服:3257982914
    Vitedoin A; Vitedoin A CFN96448 819861-40-0 C20H20O6 = 356.37 5mg QQ客服:2932563308
    (-)-5'-甲氧基异落叶松脂素-9'-O-beta-D-吡喃葡萄糖苷; (-)-5'-Methoxyisolariciresinol 3alpha-O-beta-glucopyranoside CFN95403 143236-03-7 C27H36O12 = 552.6 5mg QQ客服:3257982914
    (+)-南烛木树脂酚; (+)-Lyoniresinol CFN99488 14464-90-5 C22H28O8 = 420.5 5mg QQ客服:215959384

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产