Info: Read More
  • 中药标准品生产商,产品定制服务
  • 三七皂苷R4

    Notoginsenoside R4

    三七皂苷R4
    产品编号 CFN91142
    CAS编号 87741-77-3
    分子式 = 分子量 C59H100O27 = 1241.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The roots and rhizomes of Panax ginseng
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    三七皂苷R4 CFN91142 87741-77-3 1mg QQ客服:2159513211
    三七皂苷R4 CFN91142 87741-77-3 5mg QQ客服:2159513211
    三七皂苷R4 CFN91142 87741-77-3 10mg QQ客服:2159513211
    三七皂苷R4 CFN91142 87741-77-3 20mg QQ客服:2159513211
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Wroclaw Medical University (Poland)
  • University of Liège (Belgium)
  • Wageningen University (Netherlands)
  • The Vancouver Prostate Centre (VPC) (Canada)
  • University of Illinois (USA)
  • Massachusetts General Hospital (USA)
  • Cornell University (USA)
  • University of Minnesota (USA)
  • University of Lodz (Poland)
  • Medical University of South Carolina (USA)
  • Yale University (USA)
  • Gyeongsang National University (Korea)
  • University of Auckland (New Zealand)
  • Texas A&M University (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Biomedicines.2022, 10(5):1170
  • Nutr Res Pract.2020, 14(5):478-489.
  • Phytochem Anal.2013, 24(5):493-503
  • Front Pharmacol.2022, 13:972825.
  • J Sep Sci.2021, 44(22):4064-4081.
  • Sci Rep.2017, 7:40345
  • Mol Cells.2018, 41(8):771-780
  • Environ Toxicol.2019, 34(4):513-520.
  • Biomed Pharmacother.2020, 125:109784.
  • J Sci Food Agric.2018, 98(3):1153-1161
  • Asian Journal of Chemistry2014, 26(22):7811-7816
  • Oxid Med Cell Longev2020, 12
  • Int J Mol Sci.2018, 19(9):E2528
  • Applied Biological Chemistry2023, 66(58):112.
  • Indian J Pharm Sci.2022, 84(3):144-151
  • Oncol Rep.2019, 41(4):2453-2463
  • Sci Rep.2016, 6:25094
  • Fitoterapia.2015, 100:179-86
  • Food Res Int.2022, 157:111397.
  • Exp Neurobiol.2018, 27(3):200-209
  • Biomed Pharmacother.2021, 139:111585.
  • J Biotechnol.2020, 318:10-19.
  • VNU Journal of Science: Med.& Pharm. Sci.2022, 38(2):2588-1132.
  • ...
  • 生物活性
    Description: Reference standards.
    In vitro:
    Planta Med. 2001 Jul;67(5):417-22.
    Effects of ginsenosides from Panax ginseng on cell-to-cell communication function mediated by gap junctions.[Pubmed: 11488454 ]
    Gap junctions have been shown or are believed to be involved in the pathogenesis of many inherited and acquired human diseases. Agents that regulate the gap junction-mediated intercellular communication (GJIC) function may facilitate prevention and treatment of GJIC-involved diseases.
    METHODS AND RESULTS:
    In the present study we examined the effects of 27 ginsenosides isolated from Panax ginseng on GJIC. The results show that compounds 1 (oleanolic acid), 2 (ginsenoside-R0), 3 (ginsenoside-Rb1), 5 (ginsenoside-Rb2), 7 (ginsenoside-Rd), 8 (ginsenoside-Rg3), 12 (panaxadial), 13 (notoginsenoside R4), 17 [ginsenoside-Rg2 (20S)], 18 (ginsenoside-Rf), and 26 (ginsenoside-F3) did not obviously affect GJIC, whereas compounds 4 (ginsenoside-Rc), 6 (ginsenoside-Rb3), 9 (ginsenoside-Rd2), 10 (notoginsenoside-Fe), 11 (ginsenoside-Rh2),14 (ginsenoside-Ra1), 15 (ginsenoside-Re), 16 [ginsenoside-Rg2 (20R)], 19 (ginsenoside-Ia), 20 [ginsenoside-Rh1 (20S)], 21 [ginsenoside-Rh1 (20R)], 22 (ginsenoside-F1), 23 (protopanaxatriol), 24 (panaxatriol), 25 (ginsenoside-Rg1), and 27 (chikusetsaponin-L8) induced GJIC reductions at various degrees. Compounds 2, 7, and 8 protected against the tyrosine phosphatase inhibitor vanadate-induced GJIC reduction, while compounds 1, 5, 7, and 17 inhibited the cytokine interleukin 1 alpha (IL-1alpha)-induced reduction in GJIC. Nevertheless, no compounds protected against the protein kinase C (PKC) activator 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced GJIC inhibition. On the other hand, GJIC reductions induced by compounds 6, 9,10, 20, 21, 22, 24, and 25 were inhibited by the tyrosine kinase (TK) inhibitor genistein, while GJIC reductions induced by compounds 6, 9, 14, 16, 19, 21, and 24 were attenuated in the presence of the PKC inhibitor calphostin C. However, GJIC reductions induced by compounds 4, 23, and 27 were not inhibited either by genistein or by calphostin C.
    CONCLUSIONS:
    These data indicate that various mechanisms are responsible for effects of ginsenosides on GJIC.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 0.8055 mL 4.0277 mL 8.0554 mL 16.1108 mL 20.1386 mL
    5 mM 0.1611 mL 0.8055 mL 1.6111 mL 3.2222 mL 4.0277 mL
    10 mM 0.0806 mL 0.4028 mL 0.8055 mL 1.6111 mL 2.0139 mL
    50 mM 0.0161 mL 0.0806 mL 0.1611 mL 0.3222 mL 0.4028 mL
    100 mM 0.0081 mL 0.0403 mL 0.0806 mL 0.1611 mL 0.2014 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    达玛-20(22),24-二烯-3β,6α,12β-三醇; Quasipanaxatriol CFN95248 171903-78-9 C30H50O3 = 458.7 5mg QQ客服:1413575084
    人参皂苷MC; Ginsenoside MC CFN95232 175484-06-7 C41H70O12 = 755.0 10mg QQ客服:1413575084
    Gynosaponin I; Gynosaponin I CFN96182 1207861-69-5 C42H72O12 = 769.0 5mg QQ客服:3257982914
    人参皂苷TN2; Gynosaponin TN2 CFN95331 77658-95-8 C42H72O13 = 785.0 5mg QQ客服:1413575084
    人参皂苷F2; Ginsenoside F2 CFN99755 62025-49-4 C42H72O13 = 785.01 20mg QQ客服:2159513211
    人参皂苷Rd2; Ginsenoside Rd2 (Quinquenoside L10) CFN95231 83480-64-2 C47H80O17 = 917.2 10mg QQ客服:215959384
    七叶胆苷XVI; Gypenoside XVII CFN90193 80321-69-3 C48H82O18 = 947.16 20mg QQ客服:2159513211
    三七皂苷L13; Notoginsenoside L13 CFN95332 2485859-56-9 C47H78O17 = 915.1 5mg QQ客服:1413575084
    人参皂苷Rb2; Ginsenoside Rb2 CFN99965 11021-13-9 C53H90O22 = 1079.27 20mg QQ客服:215959384
    人参皂苷Rb3; Ginsenoside Rb3 CFN99966 68406-26-8 C53H90O22 = 1079.27 20mg QQ客服:2056216494

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产