
人参皂苷F3
Ginsenoside F3
|
|
产品编号 |
CFN99978 |
| CAS编号 |
62025-50-7 |
| 分子式 = 分子量 |
C41H70O13 = 770.99 |
| 产品纯度 |
>=98% |
| 物理属性 |
White powder |
| 化合物类型 |
Triterpenoids |
| 植物来源 |
The roots of Panax ginseng C. A. Mey. |
| ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 |
|
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| 人参皂苷F3 |
CFN99978 |
62025-50-7 |
10mg |
QQ客服:215959384 |
| 人参皂苷F3 |
CFN99978 |
62025-50-7 |
20mg |
QQ客服:215959384 |
| 人参皂苷F3 |
CFN99978 |
62025-50-7 |
50mg |
QQ客服:215959384 |
| 人参皂苷F3 |
CFN99978 |
62025-50-7 |
100mg |
QQ客服:215959384 |
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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
Universidade da Beira Interior (Germany)
Universiti Putra Malaysia(UPM) (Malaysia)
Worcester Polytechnic Institute (USA)
University of the Basque Country (Spain)
Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
Institute of Chinese Materia Medica (China)
University of Melbourne (Australia)
VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
University of Minnesota (USA)
Utrecht University (Netherlands)
University Medical Center Mainz (Germany)
The Ohio State University (USA)
Kazusa DNA Research Institute (Japan)
University of Eastern Finland (Finland)
More...
国外学术期刊发表的引用ChemFaces产品的部分文献
| Description: |
Ginsenoside F3 has immunoenhancing activity by regulating production and gene expression of type 1,type 2 cytokines in murine spleen cells. It enhances the NF-kappaB DNA binding activity induced by ConA in murine spleen cells with 10 micromol/L. |
| Targets: |
NF-kB | IL Receptor | IFN-γ |
| In vitro: |
| Acta Pharmacol Sin. 2004 Dec;25(12):1671-6. | | Immunoenhancing activity of protopanaxatriol-type ginsenoside-F3 in murine spleen cells.[Pubmed: 15569414] | To investigate the immunoenhancing activity of ginsenoside F3 in murine spleen cells and explore its mechanism.
METHODS AND RESULTS:
The enhancing effect of ginsenoside F3 on murine spleen cell proliferation was studied using [3H]thymidine incorporation assay. Effects of ginsenoside-F3 on the production of type 1 cytokines IL-2, IFN-gamma, and type 2 cytokines IL-4 and IL-10 from murine spleen cells were detected by ELISA method. Effects of ginsenoside F3 on mRNA level of cytokines IL-4, IFN-gamma, and transcription factors T-bet and GATA-3 were evaluated by RT-PCR analysis. Effect of ginsenoside F3 on NF-kappaB DNA binding activity in murine spleen cells was investigated by electrophoretic mobility shift assays (EMSA).
ginsenoside F3 at 0.1-100 micromol/L not only promoted the murine spleen cell proliferation, but also increased the production of IL-2 and IFN-gamma, while decreased the production of IL-4 and IL-10 from murine spleen cells with the maximal effect at 10 micromol/L. RT-PCR analysis displayed that ginsenoside F3 enhanced the IFN-gamma and T-bet gene expression and decreased IL-4 and GATA-3 gene expression. EMSA experiment showed that ginsenoside F3 10 micromol/L enhanced the NF-kappaB DNA binding activity induced by ConA in murine spleen cells.
CONCLUSIONS:
ginsenoside F3 has immunoenhancing activity by regulating production and gene expression of type 1 cytokines and type 2 cytokines in murine spleen cells. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.297 mL |
6.4852 mL |
12.9703 mL |
25.9407 mL |
32.4258 mL |
| 5 mM |
0.2594 mL |
1.297 mL |
2.5941 mL |
5.1881 mL |
6.4852 mL |
| 10 mM |
0.1297 mL |
0.6485 mL |
1.297 mL |
2.5941 mL |
3.2426 mL |
| 50 mM |
0.0259 mL |
0.1297 mL |
0.2594 mL |
0.5188 mL |
0.6485 mL |
| 100 mM |
0.013 mL |
0.0649 mL |
0.1297 mL |
0.2594 mL |
0.3243 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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