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  • 新原莪述烯醇

    Neoprocurcumenol

    新原莪述烯醇
    产品编号 CFN92789
    CAS编号 102130-91-6
    分子式 = 分子量 C15H22O2 = 234.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Sesquiterpenoids
    植物来源 The rhizomes of Curcuma zedoaria
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    新原莪述烯醇 CFN92789 102130-91-6 1mg QQ客服:2159513211
    新原莪述烯醇 CFN92789 102130-91-6 5mg QQ客服:2159513211
    新原莪述烯醇 CFN92789 102130-91-6 10mg QQ客服:2159513211
    新原莪述烯醇 CFN92789 102130-91-6 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Leibniz Institute of Plant Biochemistry (Germany)
  • University of East Anglia (United Kingdom)
  • Imperial College London (United Kingdom)
  • Auburn University (USA)
  • Istanbul University (Turkey)
  • Florida A&M University (USA)
  • Universidade Federal de Santa Catarina (Brazil)
  • University of Fribourg (Switzerland)
  • Mendel University in Brno (Czech Republic)
  • University of Eastern Finland (Finland)
  • University of Bonn (Germany)
  • University of Cincinnati (USA)
  • Yale University (USA)
  • Technical University of Denmark (Denmark)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Plants (Basel).2021, 10(7):1376.
  • Mol Med Rep.2014, 9(5):1653-9
  • International J of Green Pharmacy2019, 13(3)
  • China Pharmacy2015, 26(27)
  • J Biochem Mol Toxicol.2022, e23211.
  • Front Pharmacol.2021, 12:770667.
  • Food Chem.2022, 373(Pt B):131364.
  • Journal of Apicultural Research2021, 60(1).
  • J Agric Food Chem.2021, 69(11):3496-3510.
  • Nutrients.2020, 12(5):1242.
  • Plants (Basel).2021, 10(6):1119.
  • Molecules.2021, 26(23):7390.
  • Toxicol Appl Pharmacol.2021, 427:115668.
  • Cytotechnology2022, s10616
  • J Nat Med.2020, 74(1):65-75
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1124:323-330
  • Foods.2020, 9(10):1348.
  • Antioxidants (Basel).2021, 10(10):1638.
  • Appl. Sci.2020, 10(20),7374.
  • Front Chem.2023, 11:1245071.
  • Microchemical Journal2023. 191:108938
  • ACS Synth Biol.2020, 9(9):2282-2290.
  • Heliyon2020, 6(6):e04337.
  • ...
  • 生物活性
    Description: Neoprocurcumenol exerts significant toxicity on mosquito larvae.
    In vitro:
    Acta Trop. 2010 Jan;113(1):7-11.
    Efficacy of bioactive compounds from Curcuma aromatica against mosquito larvae.[Pubmed: 19712662]
    With the development of resistance to conventionally used synthetic insecticides, vector management has become acutely problematic. Hence more attention has been focused on botanicals. Therefore our present study was aimed to evaluate the efficacy of extracts from rhizomes of Curcuma aromatica against the larvae of filariasis vector mosquitoes, Culex quinquefasciatus employing standard WHO procedure at Mysore.
    METHODS AND RESULTS:
    The soxhlet extraction was carried out using non-polar organic solvent, petroleum ether. The efficacy of petroleum ether extract seemed to be effective with LC(50) and LC(90) values of 11.42 and 18.00 ppm respectively. Bioassay-guided fractionation through flash chromatography lead to the isolation of two larvicidal compounds namely 9-oxoNeoprocurcumenol and Neoprocurcumenol. Between the two, 9-oxoNeoprocurcumenol exerted significant toxicity (P<0.01) on mosquito larvae with LC(50) value of 5.81 ppm and LC(90) being 9.99 ppm compared to Neoprocurcumenol with 13.69 and 23.92 ppm of LC(50) and LC(90) values respectively.
    CONCLUSIONS:
    From the results, C. aromatica could be considered as one of the powerful candidate to bring about useful botanicals so as to prevent the resurgence of mosquito vectors.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.268 mL 21.3402 mL 42.6803 mL 85.3606 mL 106.7008 mL
    5 mM 0.8536 mL 4.268 mL 8.5361 mL 17.0721 mL 21.3402 mL
    10 mM 0.4268 mL 2.134 mL 4.268 mL 8.5361 mL 10.6701 mL
    50 mM 0.0854 mL 0.4268 mL 0.8536 mL 1.7072 mL 2.134 mL
    100 mM 0.0427 mL 0.2134 mL 0.4268 mL 0.8536 mL 1.067 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    莪术醇; Curcumenol CFN92614 19431-84-6 C15H22O2 = 234.3 20mg QQ客服:3257982914
    异莪术醇; Isocurcumenol CFN92618 24063-71-6 C15H22O2 = 234.3 20mg QQ客服:1413575084
    莪术醇; 姜黄醇; Curcumol CFN99187 4871-97-0 C15H24O2 = 236.35 20mg QQ客服:2159513211
    4beta,12-dihydroxyguaian-6,10-diene; 4beta,12-dihydroxyguaian-6,10-diene CFN90947 461644-90-6 C15H24O2 = 236.34 5mg QQ客服:215959384
    Chrysothol; Chrysothol CFN97477 911714-91-5 C15H26O2 = 238.4 5mg QQ客服:2159513211
    泽泻醇; Alismol CFN97446 87827-55-2 C15H24O = 220.4 10mg QQ客服:1413575084
    环氧泽泻烯; Alismoxide CFN99775 87701-68-6 C15H26O2 = 238.37 20mg QQ客服:1413575084
    愈创醇; Guaiol CFN96326 489-86-1 C15H26O = 222.4 5mg QQ客服:3257982914
    Teuclatriol; Teuclatriol CFN99634 152110-17-3 C15H28O3 = 256.4 5mg QQ客服:2159513211
    苍术苷A; Atractyloside A CFN98560 126054-77-1 C21H36O10 = 448.5 20mg QQ客服:1413575084

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