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  • 水仙苷

    • 水仙苷

    Narcissoside

    水仙苷
    		产品编号 CFN99773
    CAS编号 604-80-8
    分子式 = 分子量 C28H32O16 = 624.54
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Flavonoids
    植物来源 The bulbus of Narcissus tazettaL. var. chinensis Roem.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    水仙苷 CFN99773 604-80-8 10mg QQ客服：215959384
    水仙苷 CFN99773 604-80-8 20mg QQ客服：215959384
    水仙苷 CFN99773 604-80-8 50mg QQ客服：215959384
    水仙苷 CFN99773 604-80-8 100mg QQ客服：215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • University of Bonn (Germany)
  • Deutsches Krebsforschungszentrum (Germany)
  • Utrecht University (Netherlands)
  • University of Hull (United Kingdom)
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    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Appl Biol Chem.2021, 64(3),263?268
  • J Appl Biol Chem2023, 66:455−461
  • J Bone Miner Res.2017, 32(12):2415-2430
  • Food Chem.2019, 274:345-350
  • Int Immunopharmacol.2023, 7:127:111322.
  • Appl. Sci.2021, 11(19),9343.
  • Exp Parasitol.2017, 183:160-166
  • Phys Chem Chem Phys.2018, 20(23):15986-15994
  • Plant Cell Physiol.2018, 59(1):128-141
  • Journal of Ginseng Research2019, 10.1016
  • Inflammation.2022, 45(6):2529-2543.
  • Evid Based Complement Alternat Med.2021, 8707280.
  • J Biomed Sci.2020, 27(1):60.
  • Molecules.2023, 28(10):4121.
  • Food Sci Nutr.2023, 11(9):5532-5542.
  • J of L. Chroma.&Related Tech2017, 252-258
  • FEBS J.2022, 10.1111:febs.16676.
  • Biomed Pharmacother.2023, 166:115329.
  • Heliyon.2023, e12778.
  • Metabolites2023, 13(1), 3.
  • Int J Mol Sci.2023, 24(15):12397.
  • Journal of Chromatography A2020, 460942
  • Phytother Res.2019, 33(5):1490-1500
  • ...
    • 生物活性
    Description: Narcissoside is a good 15-LO and α-glucosidase inhibitor, it with synergism of B.flavum flavonoid and rutin, could be responsible for stronger protection against mitochondrial induced oxidative stress.
    Targets: AMPK | α-Glucosidase | 15-lipoxygenase
    In vitro:
    Pharmacogn Mag. 2015 Jan-Mar;11(41):14-23.
    Flavonoid profiles of three Bupleurum species and in vitro hepatoprotective of activity Bupleurum flavum Forsk.[Pubmed: 25709205]
    Bupleurum L. (Aspiaceae) species are used as herbal remedy in Chinese traditional medicine. OBJECTIVE: The aim was to investigate the flavonoids in three annual European Bupleurum species, including B. baldense, B. affine and B. flavum, and to test their antioxidant and possible hepatoprotective effects.
    METHODS AND RESULTS:
    Flavonoids from the methanol-aqueous extracts were quantified by solid-phase extraction-high-performance liquid chromatography. Bupleurum extracts (1-220 mg/ml) were tested for their antioxidant activity in DPPH and ABTS assays, as well as on isolated liver rat microsomes. In vitro hepatoprotective activity of B. flavum flavonoid (BFF) mixture and rutin, and Narcissoside, isolated from the same mixture, were evaluated on carbon tetrachloride (CCl4) and tert-butyl hydroperoxide (t-BuOOH) toxicity models in isolated rat hepatocytes. Narcissoside was the dominant flavonol glycoside in B. flavum being present at 24.21 ± 0.19 mg/g, whilst the highest content of rutin (28.63 ± 1.57 mg/g) was found in B. baldense. B. flavum possessed the strongest DPPH (IC50 22.12 μg/ml) and ABTS (IC50 118.15 μg/ml) activity. At a concentration 1 mg/ml of BFF (rutin 197.58 mg/g, narcissin 75.74 mg/g), a stronger antioxidant effect in microsomes was evidenced in comparison with silymarin, rutin and Narcissoside. The hepatoprotective effect of BFF significantly reduced the elevated levels of lactate dehydrogenase and malondialdehyde, and ameliorated glutathione, being most active in t-BuOOH-induced injury model when compared with CCl4 toxicity (P < 0.001).
    CONCLUSIONS:
    In BFF, synergism of rutin and Narcissoside could be responsible for stronger protection against mitochondrial induced oxidative stress.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6012 mL 8.0059 mL 16.0118 mL 32.0236 mL 40.0295 mL
    5 mM 0.3202 mL 1.6012 mL 3.2024 mL 6.4047 mL 8.0059 mL
    10 mM 0.1601 mL 0.8006 mL 1.6012 mL 3.2024 mL 4.0029 mL
    50 mM 0.032 mL 0.1601 mL 0.3202 mL 0.6405 mL 0.8006 mL
    100 mM 0.016 mL 0.0801 mL 0.1601 mL 0.3202 mL 0.4003 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    异鼠李素-3-O-葡萄糖苷; Isorhamnetin-3-O-beta-D-Glucoside CFN99757 5041-82-7 C22H22O12 = 478.40 10mg QQ客服：1457312923
    异鼠李素 3-O-半乳糖苷; Isorhamnetin 3-O-galactoside CFN93036 6743-92-6 C22H22O12 = 478.40 5mg QQ客服：1457312923
    鼠李亭-3-O-半乳糖苷; Rhamnetin 3-galactoside CFN95116 62858-07-5 C22H22O12 = 478.4 10mg QQ客服：3257982914
    异鼠李素-3-葡萄糖醛酸苷; Isorhamnetin 3-glucuronide CFN90568 36687-76-0 C22H20O13 = 492.39 5mg QQ客服：2159513211
    异鼠李素-3-O-新橙皮糖苷; Isorhamnetin-3-O-neohespeidoside CFN99744 55033-90-4 C28H32O16 = 624.54 20mg QQ客服：2056216494
    水仙苷; Narcissoside CFN99773 604-80-8 C28H32O16 = 624.54 20mg QQ客服：1457312923
    异鼠李素 3-O-葡萄糖基 (1->4)鼠李糖苷; Isorhamnetin-3-O-glucosyl-(1->4)-O-rhamnoside CFN95723 1135753-17-1 C28H32O16 = 624.6 5mg QQ客服：215959384
    异鼠李亭 3-龙胆二糖甙; Astragaloside CFN99170 17429-69-5 C28H32O17 = 640.55 5mg QQ客服：2056216494
    异鼠李素-3,5-O-二葡萄糖苷; Isorhamnetin 3,5-O-diglucoside CFN95488 2035413-03-5 C28H32O17 = 640.6 10mg QQ客服：215959384
    异鼠李素 3-O-呋喃芹菜糖 (1→2)[鼠李糖(1→6)]葡萄糖苷; Isorhamnetin 3-O-apiosyl (1→2)[rhamnosyl (1→6)]glucoside CFN95769 165605-18-5 C33H40O20 = 756.7 5mg QQ客服：215959384

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