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  • 七里香甙甲

    • 七里香甙甲

    Helveticoside

    七里香甙甲
    		产品编号 CFN70428
    CAS编号 630-64-8
    分子式 = 分子量 C29H42O9 = 534.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Steroids
    植物来源 The herbs of Thevetia peruviana
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    七里香甙甲 CFN70428 630-64-8 1mg QQ客服：1457312923
    七里香甙甲 CFN70428 630-64-8 5mg QQ客服：1457312923
    七里香甙甲 CFN70428 630-64-8 10mg QQ客服：1457312923
    七里香甙甲 CFN70428 630-64-8 20mg QQ客服：1457312923
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    3. 需要更多关于溶解度，使用和处理的建议？ 请发送电子邮件至：service@chemfaces.com
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • Weizmann Institute of Science (Israel)
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  • Cornell University (USA)
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    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Plant Cell Tiss Org2020, 1-16
  • Front Endocrinol (Lausanne).2020, 11:568436.
  • Molecules.2020, 25(23):5609.
  • Talanta.2023, 262:124690.
  • Chin. Med.J.Res. Prac.2017, 31(4)
  • Molecules.2023, 28(8):3490.
  • Fitoterapia.2022, 105141.
  • Molecules.2021, 26(9):2802.
  • Arch Toxicol.2017, 91(10):3225-3245
  • Food Chem.2024, 446:138870.
  • Plants (Basel).2021, 10(11):2317.
  • Medicinal Chemistry Research 2021, 30:1117-1124.
  • Rev. Chim.2020, 71(3),558-564
  • SBRAS2016, 12
  • Int J Mol Med.2016, 37(2):501-8
  • Phytochemistry.2024, 222:114102.
  • Int J Mol Sci.2019, 20(8):E1855
  • Int. J. Mol. Sci.2023, 24(20),15294.
  • Plant Cell,Tissue & Organ Culture2016, 127(1):115-121
  • LWT2021, 147:111620.
  • Environ Toxicol.2023, tox.23999.
  • J.the Korean Socie. Food Sci.&Nut.2023; 52(1):26-39.
  • Life (Basel).2021, 11(12):1399.
  • ...
    • 生物活性
    Description: Helveticoside, disulfiram, and lanatoside C as potential molecular targets in chronic obstructive pulmonary disease( COPD).
    In vitro:
    Lung, 2014, 192(1):87-93.
    Protein-Protein Interaction Network Analysis in Chronic Obstructive Pulmonary Disease.[Reference: WebLink]
    The aim of this study was to investigate the gene expression profile of chronic obstructive pulmonary disease (COPD) patients and non-COPD patients.
    METHODS AND RESULTS:
    Microarray raw data (GSE29133) was downloaded from Gene Expression Omnibus, including three COPD samples and three normal controls. Gene expression profiling was performed using Affymetrix human genome u133 plus 2.0 GeneChip. Differentially expressed genes were identified by Student's t test and genes with p < 0.05 were considered significantly changed. Up- and downregulated genes were submitted to the molecular signatures database (MSigDB) to search for a possible association with other previously published gene expression signatures. Furthermore, we constructed a COPD protein-protein interaction (PPI) network and used the connectivity map (cMap) to query for potential drugs for COPD. A total of 680 upregulated genes and 530 downregulated genes in COPD were identified. The MSigDB investigation found that upregulated genes were highly similar to gene signatures that respond to interferon and downregulated genes were similar to erythroid progenitor cells from fetal livers of E13.5 embryos with KLF1 knocked out. A PPI network consisting of 814 gene/proteins and 2,613 interactions was identified by Search Tool for the Retrieval of Interacting Genes. The cMap predicted helveticoside, disulfiram, and lanatoside C as the top three possible drugs that could perhaps treat COPD.
    CONCLUSIONS:
    Comprehensive analysis of the gene expression profile for COPD versus control reveals helveticoside, disulfiram, and lanatoside C as potential molecular targets in COPD. This evidence provides a new breakthrough in the medical treatment of patients with COPD.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8702 mL 9.351 mL 18.7021 mL 37.4042 mL 46.7552 mL
    5 mM 0.374 mL 1.8702 mL 3.7404 mL 7.4808 mL 9.351 mL
    10 mM 0.187 mL 0.9351 mL 1.8702 mL 3.7404 mL 4.6755 mL
    50 mM 0.0374 mL 0.187 mL 0.374 mL 0.7481 mL 0.9351 mL
    100 mM 0.0187 mL 0.0935 mL 0.187 mL 0.374 mL 0.4676 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    杠柳毒苷; Periplocin CFN90513 13137-64-9 C36H56O13 = 696.82 20mg QQ客服：3257982914
    Periplogenin 3-[O-beta-glucopyranosyl-(1->4)-beta-sarmentopyranoside]; Periplogenin 3-[O-beta-glucopyranosyl-(1->4)-beta-sarmentopyranoside] CFN90985 1253421-94-1 C36H56O13 = 696.83 10mg QQ客服：2159513211
    洋地黄毒甙; Digitoxin CFN98535 71-63-6 C41H64O13 = 764.94 20mg QQ客服：1457312923
    地高辛; Digoxin CFN98536 20830-75-5 C41H64O14 = 780.94 20mg QQ客服：2159513211
    羟基洋地黄毒苷; Gitoxin CFN70364 4562-36-1 C41H64O14 = 781.0 5mg QQ客服：215959384
    Stauntosaponin A; Stauntosaponin A CFN96658 1417887-91-2 C28H38O7 = 486.60 5mg QQ客服：1457312923
    蔓茎毒毛旋花子苷; Sarmentocymarin CFN89202 98633-61-5 C30H46O8 = 534.69 5mg QQ客服：2056216494
    Cryptanoside A; Cryptanoside A CFN89193 98570-81-1 C30H42O10 = 562.65 5mg QQ客服：1413575084
    黄夹次甙乙; 17alpha-Neriifolin CFN97195 7044-31-7 C30H46O8 = 534.7 5mg QQ客服：1457312923
    奥多诺甙H; Odoroside H CFN99868 18810-25-8 C30H46O8 = 534.7 5mg QQ客服：1413575084

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