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  • 黄夹甙B

    Thevetin B

    黄夹甙B
    产品编号 CFN96147
    CAS编号 27127-79-3
    分子式 = 分子量 C42H66O18 = 859.0
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Steroids
    植物来源 The herbs of Thevetia peruviana
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    黄夹甙B CFN96147 27127-79-3 1mg QQ客服:215959384
    黄夹甙B CFN96147 27127-79-3 5mg QQ客服:215959384
    黄夹甙B CFN96147 27127-79-3 10mg QQ客服:215959384
    黄夹甙B CFN96147 27127-79-3 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
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    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
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    IF=12.804(2019)

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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Phytomedicine.2021, 93:153796.
  • Metabolites.2023, 13(6):689.
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  • J Biomol Struct Dyn.2023, 1-21.
  • Pak J Pharm Sci.2018, 31:311-315
  • Proc Natl Acad Sci USA.2016, 113(30):E4407-1
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  • Cell Mol Biol (Noisy-le-grand).2023, 69(15):167-173.
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  • Microchemical Journal2018, 137:168-173
  • South African Journal of Botany2024, 168:209-220.
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  • ...
  • 生物活性
    Description: Thevetin B is a cardiac glycoside. Thevetin A and thevetin B are Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) (EC 3.6.1.3) inhibitors.
    Targets: Sodium Channel | ATPase | Potassium Channel
    In vitro:
    Forensic Sci Int. 2012 Feb 10;215(1-3):146-51.
    Method validation of a survey of thevetia cardiac glycosides in serum samples.[Pubmed: 21376490]
    A sensitive and specific liquid chromatography tandem mass spectrometry (HPLC-ESI(+)-MS/MS) procedure was developed and validated for the identification and quantification of Thevetin B and further cardiac glycosides in human serum. The seeds of Yellow Oleander (Thevetia peruviana) contain cardiac glycosides that can cause serious intoxication.
    METHODS AND RESULTS:
    A mixture of six thevetia glycosides was extracted from these seeds and characterized. Thevetin B, isolated and efficiently purified from that mixture, is the main component and can be used as evidence. Solid phase extraction (SPE) proved to be an effective sample preparation method. Digoxin-d3 was used as the internal standard. Although ion suppression occurs, the limit of detection (LOD) is 0.27 ng/ml serum for Thevetin B. Recovery is higher than 94%, and accuracy and precision were proficient.
    CONCLUSIONS:
    Method refinement was carried out with regard to developing a general screening method for cardiac glycosides. The assay is linear over the range of 0.5-8 ng/ml serum. Finally, the method was applied to a case of thevetia seed ingestion.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.1641 mL 5.8207 mL 11.6414 mL 23.2829 mL 29.1036 mL
    5 mM 0.2328 mL 1.1641 mL 2.3283 mL 4.6566 mL 5.8207 mL
    10 mM 0.1164 mL 0.5821 mL 1.1641 mL 2.3283 mL 2.9104 mL
    50 mM 0.0233 mL 0.1164 mL 0.2328 mL 0.4657 mL 0.5821 mL
    100 mM 0.0116 mL 0.0582 mL 0.1164 mL 0.2328 mL 0.291 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Stauntosaponin A; Stauntosaponin A CFN96658 1417887-91-2 C28H38O7 = 486.60 5mg QQ客服:1457312923
    蔓茎毒毛旋花子苷; Sarmentocymarin CFN89202 98633-61-5 C30H46O8 = 534.69 5mg QQ客服:1413575084
    Cryptanoside A; Cryptanoside A CFN89193 98570-81-1 C30H42O10 = 562.65 5mg QQ客服:2159513211
    黄夹次甙乙; 17alpha-Neriifolin CFN97195 7044-31-7 C30H46O8 = 534.7 5mg QQ客服:215959384
    奥多诺甙H; Odoroside H CFN99868 18810-25-8 C30H46O8 = 534.7 5mg QQ客服:3257982914
    乌沙苷元洋地黄苷; Uzarigenin digitaloside CFN97718 61217-80-9 C30H46O8 = 534.69 5mg QQ客服:1457312923
    夹竹桃它罗苷 ; Neritaloside CFN98691 465-13-4 C32H48O10 = 592.7 5mg QQ客服:2159513211
    欧夹竹桃苷; Oleandrin CFN98693 465-16-7 C32H48O9 = 576.7 20mg QQ客服:2056216494
    黄夹竹桃乙糖苷; Thevebioside CFN99245 114586-47-9 C36H56O13 = 696.8 5mg QQ客服:1457312923
    17alpha-黄夹竹桃乙糖苷; 17alpha-Thevebioside CFN99246 114613-59-1 C36H56O13 = 696.8 5mg QQ客服:1413575084

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