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  • 灵芝酸C2

    Ganoderic acid C2

    灵芝酸C2
    产品编号 CFN92054
    CAS编号 103773-62-2
    分子式 = 分子量 C30H46O7 = 518.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruit body of Ganoderma lucidum.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    灵芝酸C2 CFN92054 103773-62-2 10mg QQ客服:1457312923
    灵芝酸C2 CFN92054 103773-62-2 20mg QQ客服:1457312923
    灵芝酸C2 CFN92054 103773-62-2 50mg QQ客服:1457312923
    灵芝酸C2 CFN92054 103773-62-2 100mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Griffith University (Australia)
  • University of Leipzig (Germany)
  • Colorado State University (USA)
  • Helmholtz Zentrum München (Germany)
  • Hamdard University (India)
  • Srinakharinwirot University (Thailand)
  • University of Maryland School of Medicine (USA)
  • Universiti Sains Malaysia (Malaysia)
  • Universit?t Basel (Switzerland)
  • University of the Basque Country (Spain)
  • Leibniz Institute of Plant Biochemistry (Germany)
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  • Massachusetts General Hospital (USA)
  • Utrecht University (Netherlands)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Molecules.2021, 26(8):2161.
  • Molecules.2019, 24(10):E1930
  • J Ethnopharmacol.2022, 289:115018.
  • Legume Science2021, 3(4): e101.
  • Nat Prod Communications2018, 10.1177
  • The Journal of Internal Korean Medicine2015, 36(4):486-497
  • Molecules.2018, 23(11):E2837
  • Food Addit Contam Part A Chem Anal Control Expo Risk Assess.2020, 37(9):1437-1448.
  • Advances in Traditional Medicine2020, 10.1007
  • Cancer Lett. 2023, 18:216584.
  • Advances in Traditional Medicine 2021, 21:779-789.
  • Food Science and Biotechnology2023, 2023:1007
  • Front Pharmacol.2022, 13:883475.
  • ACS Synth Biol.2022, doi: 10.1021.
  • Food Chem.2021, 360:130063.
  • Molecules.2020, 25(9):2081.
  • Biotechnol Bioeng.2020, 117(7):2198-2208.
  • Mediators Inflamm.2016, 2016:7216912
  • Antioxidants (Basel).2022, 11(12):2327.
  • Phytomedicine.2015, 22(14):1262-8
  • Korean J of Food Science&Technology 2017, 49(2):146-150
  • Molecules.2021, 26(9):2791.
  • J Mol Recognit.2020, 33(2):e2819
  • ...
  • 生物活性
    Description: Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen.
    Targets: Histamine Receptor | Immunology & Inflammation related
    In vitro:
    J Pharm Biomed Anal. 2013 Mar 5;75:64-73.
    Structural characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry.[Pubmed: 23312386]

    METHODS AND RESULTS:
    The metabolites and pharmacokinetics of ganoderic acid C2 (GAC2), a bioactive triterpenoid in Ganoderma lucidum in rat plasma were investigated by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). Totally, ten minor phase I metabolites of GAC2 were characterized after oral administration of GAC2, on the basis of their mass fragmentation pathways or direct comparison with authentic compounds by high-performance liquid chromatography coupled with diode array detection and electrospray ion trap tandem mass spectrometry (HPLC-DAD-ESI-MS(n)), and liquid chromatography coupled with electrospray ionization hybrid ion trap and time-of-flight mass spectrometry (LC-ESI-IT-TOF/MS) methods. Moreover, a rapid and specific method for quantification of GAC2 in rat plasma after oral administration was developed by using a liquid-liquid extraction procedure and HPLC-ESI-MS/MS analysis.
    CONCLUSIONS:
    It is the first time to report the metabolites and pharmacokinetics of GAC2.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.9279 mL 9.6395 mL 19.279 mL 38.5579 mL 48.1974 mL
    5 mM 0.3856 mL 1.9279 mL 3.8558 mL 7.7116 mL 9.6395 mL
    10 mM 0.1928 mL 0.9639 mL 1.9279 mL 3.8558 mL 4.8197 mL
    50 mM 0.0386 mL 0.1928 mL 0.3856 mL 0.7712 mL 0.9639 mL
    100 mM 0.0193 mL 0.0964 mL 0.1928 mL 0.3856 mL 0.482 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    新化合物20; New compound 20 CFN95545 N/A C30H42O7 = 514.7 5mg QQ客服:1457312923
    丹芝酸A; Ganolucidic acid A CFN90299 98665-21-5 C30H44O6 = 500.67 5mg QQ客服:1457312923
    丹芝酸B; Ganolucidic acid B CFN95513 98683-75-1 C30H46O6 = 502.7 5mg QQ客服:3257982914
    灵芝酸B; Ganoderic acid B CFN92052 81907-61-1 C30H44O7 = 516.7 20mg QQ客服:1457312923
    灵芝酸B甲酯; Methyl ganoderate B CFN95551 81907-65-5 C31H46O7 = 530.7 5mg QQ客服:3257982914
    灵芝烯酸B; Ganoderenic acid B CFN92991 100665-41-6 C30H42O7 = 514.65 10mg QQ客服:215959384
    灵芝烯酸B甲酯; Methyl ganoderenate B CFN95534 N/A C31H44O7 = 528.7 5mg QQ客服:1457312923
    3beta,7beta,12beta-三羟基-11,15,23-三羰基-羊毛甾-8,20-二烯-26-酸; (3beta,7beta,12beta,20Z)- 3,7,12- trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid CFN91782 1961358-02-0 C30H42O8 = 530.66 5mg QQ客服:3257982914
    灵芝酸C2; Ganoderic acid C2 CFN92054 103773-62-2 C30H46O7 = 518.7 20mg QQ客服:3257982914
    灵芝酸A; Ganoderic acid A CFN92051 81907-62-2 C30H44O7 = 516.7 20mg QQ客服:1457312923

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