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  • 灵芝酸C2

    Ganoderic acid C2

    灵芝酸C2
    产品编号 CFN92054
    CAS编号 103773-62-2
    分子式 = 分子量 C30H46O7 = 518.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruit body of Ganoderma lucidum.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    灵芝酸C2 CFN92054 103773-62-2 10mg QQ客服:2159513211
    灵芝酸C2 CFN92054 103773-62-2 20mg QQ客服:2159513211
    灵芝酸C2 CFN92054 103773-62-2 50mg QQ客服:2159513211
    灵芝酸C2 CFN92054 103773-62-2 100mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Osmania University (India)
  • Shanghai University of TCM (China)
  • Donald Danforth Plant Science Center (USA)
  • Medical University of Gdansk (Poland)
  • University of Oslo (Norway)
  • University of Maryland School of Medicine (USA)
  • Hamdard University (India)
  • The Ohio State University (USA)
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  • Uniwersytet Gdański (Poland)
  • MTT Agrifood Research Finland (Finland)
  • University of Parma (Italy)
  • Lodz University of Technology (Poland)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Biol Chem.2014, 289(3):1723-31
  • Indian J Pharm Sci.2022, 84(4): 874-882.
  • Food Analytical Methods2020, 1-10
  • Phytomedicine.2018, 40:37-47
  • Nat Chem Biol.2018, 14(8):760-763
  • J Herbmed Pharmacol.2018, 7(4):280-286
  • Toxicol Appl Pharmacol.2022, 434:115815.
  • Agronomy 2021, 11(3),502.
  • Pharmaceuticals.2022, 15(4), 402.
  • LWT2021, 138:110630.
  • Processes 2021, 9(5),894.
  • Journal of Third Military Medical University2019, 41(2):110-115
  • J Int Med Res.2021, 49(7):3000605211032849.
  • Cell Physiol Biochem.2019, 52(6):1255-1266
  • J Ethnopharmacol.2017, 197:157-164
  • BMC Complement Altern Med.2017, 17(1):384
  • Biomed Pharmacother.2021, 137:111362.
  • Toxicol Rep.2021, 8:1131-1142.
  • CZECH MYCOLOGY2021, 73(1):1-19.
  • Vietnam Journal of Science2022,64(2):69-75.
  • Biomedicines.2020, 8(11):486.
  • Vojnosanit Pregl2016, 75(00):391-391
  • Univerzita Karlova2021, 20.500.11956.
  • ...
  • 生物活性
    Description: Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen.
    Targets: Histamine Receptor | Immunology & Inflammation related
    In vitro:
    J Pharm Biomed Anal. 2013 Mar 5;75:64-73.
    Structural characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry.[Pubmed: 23312386]

    METHODS AND RESULTS:
    The metabolites and pharmacokinetics of ganoderic acid C2 (GAC2), a bioactive triterpenoid in Ganoderma lucidum in rat plasma were investigated by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). Totally, ten minor phase I metabolites of GAC2 were characterized after oral administration of GAC2, on the basis of their mass fragmentation pathways or direct comparison with authentic compounds by high-performance liquid chromatography coupled with diode array detection and electrospray ion trap tandem mass spectrometry (HPLC-DAD-ESI-MS(n)), and liquid chromatography coupled with electrospray ionization hybrid ion trap and time-of-flight mass spectrometry (LC-ESI-IT-TOF/MS) methods. Moreover, a rapid and specific method for quantification of GAC2 in rat plasma after oral administration was developed by using a liquid-liquid extraction procedure and HPLC-ESI-MS/MS analysis.
    CONCLUSIONS:
    It is the first time to report the metabolites and pharmacokinetics of GAC2.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.9279 mL 9.6395 mL 19.279 mL 38.5579 mL 48.1974 mL
    5 mM 0.3856 mL 1.9279 mL 3.8558 mL 7.7116 mL 9.6395 mL
    10 mM 0.1928 mL 0.9639 mL 1.9279 mL 3.8558 mL 4.8197 mL
    50 mM 0.0386 mL 0.1928 mL 0.3856 mL 0.7712 mL 0.9639 mL
    100 mM 0.0193 mL 0.0964 mL 0.1928 mL 0.3856 mL 0.482 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    12-羟基灵芝酸D; 12-Hydroxyganoderic acid D CFN91921 942950-96-1 C30H42O8 = 530.65 5mg QQ客服:2056216494
    12-乙酰氧基灵芝酸D; 12-Acetoxy ganoderic acid D CFN95535 N/A C32H44O9 = 572.7 5mg QQ客服:2159513211
    12β-灵芝酸M; Ganoderic acid M CFN90747 100761-17-9 C30H42O8 = 530.7 10mg QQ客服:1413575084
    灵芝酸Z; Ganoderic acid Z CFN90295 294674-09-2 C30H42O7 = 514.66 5mg QQ客服:3257982914
    灵芝酸AM1; Ganoderic acid AM1 CFN90296 149507-55-1 C30H42O7 = 514.66 5mg QQ客服:2159513211
    Ethyl ganoderate J; Ethyl ganoderate J CFN92576 1189555-95-0 C32H46O7 = 542.7 5mg QQ客服:2056216494
    灵芝酸E甲酯; Methyl ganoderate E CFN95582 98718-43-5 C31H42O7 = 526.7 5mg QQ客服:2056216494
    Hainanic acid B; Hainanic acid B CFN95526 1637737-46-2 C30H42O7 = 514.7 5mg QQ客服:2056216494
    新化合物18; New compound 18 CFN95527 N/A C30H44O7 = 516.7 5mg QQ客服:215959384
    新化合物20; New compound 20 CFN95545 N/A C30H42O7 = 514.7 5mg QQ客服:1457312923

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