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  • 郁金二酮

    Curcumadione

    郁金二酮
    产品编号 CFN92617
    CAS编号 116425-36-6
    分子式 = 分子量 C15H22O2 = 234.3
    产品纯度 >=98%
    物理属性 Cryst.
    化合物类型 Sesquiterpenoids
    植物来源 The rhizomes of Curcuma wenyujin
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    郁金二酮 CFN92617 116425-36-6 1mg QQ客服:215959384
    郁金二酮 CFN92617 116425-36-6 5mg QQ客服:215959384
    郁金二酮 CFN92617 116425-36-6 10mg QQ客服:215959384
    郁金二酮 CFN92617 116425-36-6 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Ateneo de Manila University (Philippines)
  • Max-Planck-Insitut (Germany)
  • Biotech R&D Institute (USA)
  • Max Rubner-Institut (MRI) (Germany)
  • Utah State University (USA)
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  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Antioxidants (Basel).2022, 11(10):1929.
  • J Enzyme Inhib Med Chem.2019, 34(1):134-143
  • J of Physics Conference Series2019, 1349(1)
  • Int J Immunopathol Pharmacol.2019, 33:2058738419857537
  • J Pharm Biomed Anal.2021, 196:113931.
  • J Food Sci.2022, 87(11):4905-4916.
  • Analytical Letters.2020, doi 10.1008
  • Fitoterapia.2021, 153:104995.
  • J Adv Res.2019, 17:85-94
  • J Sep Sci.2018, 41(11):2488-2497
  • Inflammation.2021, doi: 10.1007
  • Phytochemistry2018, 15:83-92
  • Nanjing University of Chinese Medicine2022, 345930.
  • Front Microbiol.2020, 11:583594.
  • Planta Med.2019, 85(9-10):766-773
  • Metabolites2023, 13(1), 3.
  • Sci Rep.2015, 5:13194
  • The Korea Journal of Herbology2016, 29-35
  • Saudi Pharm J.2019, 27(1):145-153
  • Evid Based Complement Alternat Med.2017, 2017:7383104
  • Plants (Basel).2021, 10(4):702.
  • Sci Rep. 2017, 8207(7)
  • Pak J Pharm Sci.2019, 32(6)
  • ...
  • 生物活性
    Description: Curcumadione shows certain acetylcholinesterase inhibitory activity.
    Targets: AChR
    In vitro:
    Journal of Shandong University, 2013,48(7):20-3.
    Chemical constituents of Curcuma xanthorrhiza Roxb. and their acetylcholinesterase inhibitory activity[Reference: WebLink]

    METHODS AND RESULTS:
    Chemical constituents from Curcuma xanthorrhiza Roxb. (Zingiberaceae) rhizome were isolated and purified by column chromatography (silica gel, RP silica gel MPLC, HPLC) and their structures were elucidated on the basis of spectral analyses. Six compounds were identified by MS and NMR spectroscopy as zederone(I), beta-sitosterol(II), Guai-1(10),3,5,7(11),8-pentaen-2-on-11,8-olide(III), Curcumadione(IV), Curcumenone (V), Cuparenol (VI). Compound III and VI were isolated for the first time from the plants of Zingiberaceae, and compound IV and V were isolated from Curcuma xanthorrhiza Roxb. for the first time. Meanwhile, the acetylcholinesterase inhibitory activity of the isolated compounds was evaluated.
    CONCLUSIONS:
    Compounds IV and VI showed certain inhibitory activity, the minimum inhibitory quantity of IV on TLC bioautography test was 95ug.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.268 mL 21.3402 mL 42.6803 mL 85.3606 mL 106.7008 mL
    5 mM 0.8536 mL 4.268 mL 8.5361 mL 17.0721 mL 21.3402 mL
    10 mM 0.4268 mL 2.134 mL 4.268 mL 8.5361 mL 10.6701 mL
    50 mM 0.0854 mL 0.4268 mL 0.8536 mL 1.7072 mL 2.134 mL
    100 mM 0.0427 mL 0.2134 mL 0.4268 mL 0.8536 mL 1.067 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    1,6-O,O-二乙酰大花旋覆花内酯; 1,6-O,O-Diacetylbritannilactone CFN89518 1286694-67-4 C19H26O6 = 350.40 5mg QQ客服:3257982914
    1-O-乙酰-6β-O-异丁酰旋覆花内酯; 1-O-Acetyl-6beta-O-Isobutyrylbritannilactone CFN92598 1087072-50-1 C21H30O6 = 378.5 5mg QQ客服:1457312923
    1-O-乙酰基-6alpha-O-(2-甲基丁酰)大花旋覆花内酯; 1-O-Acetyl-6alpha-O-(2-methylbutyryl)britannilactone CFN89470 1932687-71-2 C22H32O6 = 392.48 5mg QQ客服:2056216494
    二大花旋覆花内酯 B; Dibritannilactone B CFN89501 1829580-18-8 C34H46O9 = 598.72 5mg QQ客服:3257982914
    天名精内酯酮; Carabrone CFN99825 1748-81-8 C15H20O3 = 248.3 5mg QQ客服:215959384
    二氢莪术双环烯酮; Dihydrocurcumenone CFN92649 142717-57-5 C15H24O2 = 236.4 5mg QQ客服:2159513211
    莪术双环烯酮; Curcumenone CFN92026 100347-96-4 C15H22O2 = 234.3 5mg QQ客服:3257982914
    Curcumadionol; Curcumadionol CFN92653 1235984-45-8 C15H20O3 = 248.3 5mg QQ客服:3257982914
    (1R-顺式)-5-甲基-alpha-亚甲基-4-(3-氧代丁基)-3-环庚烯-1-乙酸; 4-Oxobedfordiaic acid CFN97170 68799-38-2 C15H22O3 = 250.3 5mg QQ客服:1457312923
    3-Hydroxy-4,15-dinor-1(5)-xanthen-12,8-olide; 3-Hydroxy-4,15-dinor-1(5)-xanthen-12,8-olide CFN99095 1093207-99-8 C13H20O3 = 224.3 5mg QQ客服:3257982914

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