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  • Curcolonol

    Curcolonol

    Curcolonol
    产品编号 CFN92650
    CAS编号 217817-09-9
    分子式 = 分子量 C15H20O4 = 264.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Sesquiterpenoids
    植物来源 The rhizomes of Curcuma zedoaria
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Curcolonol CFN92650 217817-09-9 1mg QQ客服:215959384
    Curcolonol CFN92650 217817-09-9 5mg QQ客服:215959384
    Curcolonol CFN92650 217817-09-9 10mg QQ客服:215959384
    Curcolonol CFN92650 217817-09-9 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Johannes Gutenberg University Mainz (JGU) (Germany)
  • Semmelweis Unicersity (Hungary)
  • VIT University (India)
  • University of Madras (India)
  • University of Hull (United Kingdom)
  • Copenhagen University (Denmark)
  • The University of Newcastle (Australia)
  • Aveiro University (Portugal)
  • Cancer Research Initatives Foundation(CARIF) (Malaysia)
  • Charles University in Prague (Czech Republic)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • University of Bonn (Germany)
  • Heidelberg University (Germany)
  • University of Eastern Finland (Finland)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Front. Pharmacol.2022, 901563.
  • BMC Complement Altern Med.2016, 16:213
  • Int J Mol Sci.2022, 23(5):2796.
  • Journal of Functional Foods2017, 30:30-38
  • J of the Korean Society of Food Science and Nutrition2019, 32(2):148-154
  • Int J Biol Macromol.2018, 112:1093-1103
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1126-1127:121743
  • Acta Physiologiae Plantarum2015, 37:1736
  • Phytother Res.2019, 33(7):1784-1793
  • Acta Pharmaceutica Hungarica2016, 86:35-40
  • Chin J Appl. Physiol.2019, 35(3):283-288
  • Nat Plants.2016, 3:16205
  • Asian Journal of Chemistry2014, 26(8):2425
  • Plant Cell Tiss Org2020, 1-16
  • Plant Pathology2022, 10.1111:ppa.13651.
  • Nutrients.2017, 10(1)
  • Food Sci Nutr.2019, 8(1):246-256
  • Int J Mol Sci.2022, 23(21):13112.
  • Appl. Sci. 2021, 11(8),3437.
  • Anat Rec2018, 24264
  • J Nat Med.2022, 76(1):59-67.
  • Korean Journal of Pharmacognosy2014, 113-120
  • Food Sci Biotechnol.2016, 25(5):1437-1442
  • ...
  • 生物活性
    Description: Standard reference
    In vitro:
    J Nat Prod. 1998 Dec;61(12):1531-4.
    Cytotoxicity of curcuminoids and some novel compounds from Curcuma zedoaria.[Pubmed: 9868158]

    METHODS AND RESULTS:
    Bioassay-directed fractionation of an EtOH extract of Curcuma zedoaria led to isolation of an active curcuminoid, which was identified as demethoxycurcumin (2) by comparison of its 1H and 13C NMR spectra with literature data and by direct comparison with synthetic material. Curcumin (1) and bisdemethoxycurcumin (3) were also obtained. Curcuminoids (1-3) were synthesized and demonstrated to be cytotoxic against human ovarian cancer OVCAR-3 cells.
    CONCLUSIONS:
    The observed CD50 values of 1, 2, and 3 were 4.4, 3.8, and 3.1 microg/mL, respectively. Three additional novel compounds, 3, 7-dimethylindan-5-carboxylic acid (4), Curcolonol (5), and guaidiol (6), were also isolated from the EtOH extract. The structures and relative stereochemistry of 4-6 were determined by spectroscopic methods and X-ray crystallographic analysis.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.7836 mL 18.9179 mL 37.8358 mL 75.6716 mL 94.5895 mL
    5 mM 0.7567 mL 3.7836 mL 7.5672 mL 15.1343 mL 18.9179 mL
    10 mM 0.3784 mL 1.8918 mL 3.7836 mL 7.5672 mL 9.4589 mL
    50 mM 0.0757 mL 0.3784 mL 0.7567 mL 1.5134 mL 1.8918 mL
    100 mM 0.0378 mL 0.1892 mL 0.3784 mL 0.7567 mL 0.9459 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane; 1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane CFN89321 59742-11-9 C19H24O5 = 332.39 5mg QQ客服:2056216494
    6beta-Angeloyloxy-1beta,10beta-epoxy-9-oxofuranoeremophilane; 6beta-Angeloyloxy-1beta,10beta-epoxy-9-oxofuranoeremophilane CFN89320 59780-08-4 C20H24O5 = 344.40 5mg QQ客服:2056216494
    莪术呋喃烯酮; Curzerenone CFN92027 20493-56-5 C15H18O2 = 230.3 10mg QQ客服:3257982914
    表莪术呋喃烯酮; Epicurzerenone CFN92613 20085-85-2 C15H18O2 = 230.3 5mg QQ客服:2159513211
    异乌药内酯; Isolinderalactone CFN99762 957-66-4 C15H16O3 = 244.29 10mg QQ客服:1457312923
    苍术酮; Atractylone CFN92066 6989-21-5 C15H20O = 216.3 5mg QQ客服:1413575084
    乌药醇; Linderene CFN90639 26146-27-0 C15H18O2 = 230.3 10mg QQ客服:1457312923
    乌药醇乙酸酯; Linderene acetate CFN91930 26146-28-1 C17H20O3 = 272.34 5mg QQ客服:215959384
    Strychnistenolide; Strychnistenolide CFN91933 332372-09-5 C15H18O4 = 262.30 5mg QQ客服:2159513211
    8beta,9alpha-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide; 8beta,9alpha-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide CFN91948 956707-04-3 C15H18O4 = 262.30 5mg QQ客服:2159513211

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