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  • 中药标准品生产商,产品定制服务
  • 姜黄醇酮

    Curcolone

    姜黄醇酮
    产品编号 CFN92651
    CAS编号 17015-43-9
    分子式 = 分子量 C15H18O3 = 246.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Sesquiterpenoids
    植物来源 The rhizomes of Curcuma zedoaria
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    姜黄醇酮 CFN92651 17015-43-9 1mg QQ客服:215959384
    姜黄醇酮 CFN92651 17015-43-9 5mg QQ客服:215959384
    姜黄醇酮 CFN92651 17015-43-9 10mg QQ客服:215959384
    姜黄醇酮 CFN92651 17015-43-9 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Kitasato University (Japan)
  • Georgia Institute of Technology (USA)
  • Universidad Industrial de Santander (Colombia)
  • Univerzita Karlova v Praze (Czech Republic)
  • Institute of Tropical Disease Universitas Airlangga (Indonesia)
  • National Cancer Institute (USA)
  • University of Leipzig (Germany)
  • Utrecht University (Netherlands)
  • Sant Gadge Baba Amravati University (India)
  • Guangzhou Institutes of Biomedicine and Health (China)
  • University of Minnesota (USA)
  • Medizinische Universit?t Wien (Austria)
  • Charles University in Prague (Czech Republic)
  • University of Ioannina (Greece)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Pharm Biomed Anal.2019, 172:268-277
  • RSC Adv.2018, 32621-32636
  • Mol Cell.2017, 68(4):673-685
  • Molecules.2019, 24(17):E3127
  • Pharmaceutical Chemistry Journal2019, 52(12):986-991
  • J of the Korean Society of Food Science and Nutrition2016, 45(7):1017-1025
  • Plants (Basel).2020, 9(11):1422.
  • Heinrich Heine University Dusseldorf2021, 62203.
  • Food Chem Toxicol.2023, 176:113802.
  • Foods.2022, 11(6):882.
  • Trop J Nat Prod Res.2019, 3(1):6-9
  • J Chromatogr B Analyt Technol Biomed Life Sci.2021, 1187:123012.
  • Oncol Rep.2016, 35(3):1356-64
  • Saudi Pharmaceutical Journal2023, 31(12):101829
  • J Med Food.2020, 23(6):633-640.
  • Applied Biological Chemistry2023, 66(58):112.
  • Drug Chem Toxicol.2020, 1-12.
  • Phytomedicine.2019, 56:48-56
  • Molecules.2020, 25(17):3783.
  • Foods.2022, 11(12):1773.
  • Molecules.2022, 27(21):7514.
  • J Biomol Struct Dyn.2022, 1-21.
  • Molecules.2022, 27(19):6681.
  • ...
  • 生物活性
    Description: Curcolone exhibits inhibition against collagen-induced platelet aggregation at 100 uM, it also inhibit arachidonic acid (AA)-induced platelet aggregation at 100 uM.
    In vitro:
    Molecules, 2016, 21(10):E1385.
    New Sesquiterpenoids and Anti-Platelet Aggregation Constituents from the Rhizomes of Curcuma zedoaria.[Pubmed: 27763530 ]

    METHODS AND RESULTS:
    Two new sesquiterpenoids—13-hydroxycurzerenone (1) and 1-oxocurzerenone (2)—have been isolated from the rhizomes of Curcuma zedoaria, together with 13 known compounds (3–15). The structures of two new compounds were determined through spectroscopic and MS analyses. Among the isolated compounds, 13-hydroxycurzerenone (1), 1-oxocurzerenone (2), curzerenone (3), germacrone (4), Curcolone (5), procurcumenol (6), ermanin (7), curcumin (8), and a mixture of stigmast-4-en-3,6-dione (12) and stigmasta-4,22-dien-3,6-dione (13) exhibited inhibition (with inhibition % in the range of 21.28%–67.58%) against collagen-induced platelet aggregation at 100 μM.
    CONCLUSIONS:
    Compounds 1, 5, 7, 8, and the mixture of 12 and 13 inhibited arachidonic acid (AA)-induced platelet aggregation at 100 μM with inhibition % in the range of 23.44%–95.36%.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.0601 mL 20.3004 mL 40.6009 mL 81.2018 mL 101.5022 mL
    5 mM 0.812 mL 4.0601 mL 8.1202 mL 16.2404 mL 20.3004 mL
    10 mM 0.406 mL 2.03 mL 4.0601 mL 8.1202 mL 10.1502 mL
    50 mM 0.0812 mL 0.406 mL 0.812 mL 1.624 mL 2.03 mL
    100 mM 0.0406 mL 0.203 mL 0.406 mL 0.812 mL 1.015 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Strychnistenolide; Strychnistenolide CFN91933 332372-09-5 C15H18O4 = 262.30 5mg QQ客服:1457312923
    8beta,9alpha-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide; 8beta,9alpha-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide CFN91948 956707-04-3 C15H18O4 = 262.30 5mg QQ客服:2159513211
    姜黄醇酮; Curcolone CFN92651 17015-43-9 C15H18O3 = 246.3 5mg QQ客服:1457312923
    Zedoarofuran; Zedoarofuran CFN92619 213833-34-2 C15H20O4 = 264.3 5mg QQ客服:215959384
    Curcolonol; Curcolonol CFN92650 217817-09-9 C15H20O4 = 264.3 5mg QQ客服:2056216494
    1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane; 1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane CFN89321 59742-11-9 C19H24O5 = 332.39 5mg QQ客服:2056216494
    6beta-Angeloyloxy-1beta,10beta-epoxy-9-oxofuranoeremophilane; 6beta-Angeloyloxy-1beta,10beta-epoxy-9-oxofuranoeremophilane CFN89320 59780-08-4 C20H24O5 = 344.40 5mg QQ客服:3257982914
    莪术呋喃烯酮; Curzerenone CFN92027 20493-56-5 C15H18O2 = 230.3 20mg QQ客服:1457312923
    表莪术呋喃烯酮; Epicurzerenone CFN92613 20085-85-2 C15H18O2 = 230.3 5mg QQ客服:1457312923
    异乌药内酯; Isolinderalactone CFN99762 957-66-4 C15H16O3 = 244.29 10mg QQ客服:3257982914

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