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  • 中药标准品生产商,产品定制服务
  • 姜黄醇酮

    Curcolone

    姜黄醇酮
    产品编号 CFN92651
    CAS编号 17015-43-9
    分子式 = 分子量 C15H18O3 = 246.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Sesquiterpenoids
    植物来源 The rhizomes of Curcuma zedoaria
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    姜黄醇酮 CFN92651 17015-43-9 1mg QQ客服:215959384
    姜黄醇酮 CFN92651 17015-43-9 5mg QQ客服:215959384
    姜黄醇酮 CFN92651 17015-43-9 10mg QQ客服:215959384
    姜黄醇酮 CFN92651 17015-43-9 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
  • Mahidol University (Thailand)
  • University of Cincinnati (USA)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • Complutense University of Madrid (Spain)
  • Universite Libre de Bruxelles (Belgium)
  • University of Pretoria (South Africa)
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  • Aveiro University (Portugal)
  • Universidad Miguel Hernández (Spain)
  • Kitasato University (Japan)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Front Plant Sci.2022, 12:811166.
  • Nutrients2020, 12(2):488
  • Eur J Neurosci.2021, 53(11):3548-3560.
  • Journal of Apicultural Research2021, 60(1).
  • Chem Biol Interact.2016, 258:59-68
  • Korean J Dent Mater.2018, 45(2):139-146
  • Int J Mol Sci.2019, 20(8):E1855
  • J of Applied Biological Chem.2020, 63(2):147-152
  • Neuropharmacology.2018, 131:68-82
  • Applied Biological Chemistry 2021, 64(75)
  • Drug Des Devel Ther.2020, 14:969-976.
  • J Chromatogr Sci.2015, 53(5):824-9
  • Food Funct.2022, 13(23):12105-12120.
  • JLiquid Chromatography & Related Tech.2021, 10826076.
  • Biomedicine & Pharmacotherapy2020, 125:109950
  • Front Neurosci.2019, 13:1091
  • Front Microbiol.2020, 11:583594.
  • Mediators Inflamm.2016, 2016:7216912
  • Journal of Food Quality2022, P:13, 6256310.
  • Molecules.2019, 24(24):E4536
  • Asian J Beauty Cosmetol2021, 19(1): 57-64.
  • Med Sci Monit.2019, 25:9499-9508
  • Pathogens.2018, 7(3):E62
  • ...
  • 生物活性
    Description: Curcolone exhibits inhibition against collagen-induced platelet aggregation at 100 uM, it also inhibit arachidonic acid (AA)-induced platelet aggregation at 100 uM.
    In vitro:
    Molecules, 2016, 21(10):E1385.
    New Sesquiterpenoids and Anti-Platelet Aggregation Constituents from the Rhizomes of Curcuma zedoaria.[Pubmed: 27763530 ]

    METHODS AND RESULTS:
    Two new sesquiterpenoids—13-hydroxycurzerenone (1) and 1-oxocurzerenone (2)—have been isolated from the rhizomes of Curcuma zedoaria, together with 13 known compounds (3–15). The structures of two new compounds were determined through spectroscopic and MS analyses. Among the isolated compounds, 13-hydroxycurzerenone (1), 1-oxocurzerenone (2), curzerenone (3), germacrone (4), Curcolone (5), procurcumenol (6), ermanin (7), curcumin (8), and a mixture of stigmast-4-en-3,6-dione (12) and stigmasta-4,22-dien-3,6-dione (13) exhibited inhibition (with inhibition % in the range of 21.28%–67.58%) against collagen-induced platelet aggregation at 100 μM.
    CONCLUSIONS:
    Compounds 1, 5, 7, 8, and the mixture of 12 and 13 inhibited arachidonic acid (AA)-induced platelet aggregation at 100 μM with inhibition % in the range of 23.44%–95.36%.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.0601 mL 20.3004 mL 40.6009 mL 81.2018 mL 101.5022 mL
    5 mM 0.812 mL 4.0601 mL 8.1202 mL 16.2404 mL 20.3004 mL
    10 mM 0.406 mL 2.03 mL 4.0601 mL 8.1202 mL 10.1502 mL
    50 mM 0.0812 mL 0.406 mL 0.812 mL 1.624 mL 2.03 mL
    100 mM 0.0406 mL 0.203 mL 0.406 mL 0.812 mL 1.015 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Zedoarofuran; Zedoarofuran CFN92619 213833-34-2 C15H20O4 = 264.3 5mg QQ客服:2056216494
    Curcolonol; Curcolonol CFN92650 217817-09-9 C15H20O4 = 264.3 5mg QQ客服:1457312923
    1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane; 1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane CFN89321 59742-11-9 C19H24O5 = 332.39 5mg QQ客服:2159513211
    6beta-Angeloyloxy-1beta,10beta-epoxy-9-oxofuranoeremophilane; 6beta-Angeloyloxy-1beta,10beta-epoxy-9-oxofuranoeremophilane CFN89320 59780-08-4 C20H24O5 = 344.40 5mg QQ客服:2056216494
    莪术呋喃烯酮; Curzerenone CFN92027 20493-56-5 C15H18O2 = 230.3 10mg QQ客服:215959384
    表莪术呋喃烯酮; Epicurzerenone CFN92613 20085-85-2 C15H18O2 = 230.3 5mg QQ客服:2159513211
    异乌药内酯; Isolinderalactone CFN99762 957-66-4 C15H16O3 = 244.29 10mg QQ客服:1413575084
    苍术酮; Atractylone CFN92066 6989-21-5 C15H20O = 216.3 5mg QQ客服:2159513211
    乌药醇; Linderene CFN90639 26146-27-0 C15H18O2 = 230.3 10mg QQ客服:1457312923
    乌药醇乙酸酯; Linderene acetate CFN91930 26146-28-1 C17H20O3 = 272.34 5mg QQ客服:1413575084

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