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  • 莪术呋喃烯酮

    Curzerenone

    莪术呋喃烯酮
    产品编号 CFN92027
    CAS编号 20493-56-5
    分子式 = 分子量 C15H18O2 = 230.3
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Sesquiterpenoids
    植物来源 The rhizomes of Curcuma zedoaria.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    莪术呋喃烯酮 CFN92027 20493-56-5 10mg QQ客服:2159513211
    莪术呋喃烯酮 CFN92027 20493-56-5 20mg QQ客服:2159513211
    莪术呋喃烯酮 CFN92027 20493-56-5 50mg QQ客服:2159513211
    莪术呋喃烯酮 CFN92027 20493-56-5 100mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • China Medical University (Taiwan)
  • University of Liège (Belgium)
  • University of Pretoria (South Africa)
  • Nanjing University of Chinese Medicine (China)
  • Sanford Burnham Medical Research Institute (USA)
  • University of Toulouse (France)
  • Universitas islam negeri Jakarta (Indonesia)
  • Wageningen University (Netherlands)
  • University of the Basque Country (Spain)
  • Chulalongkorn University (Thailand)
  • Biotech R&D Institute (USA)
  • University of Padjajaran (Indonesia)
  • Agricultural Research Organization (ARO) (Israel)
  • University of Auckland (New Zealand)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Holistic Integrative Pharm.2023, 4(1):14-28
  • J Cell Mol Med.2021, 25(5):2645-2654.
  • Chin Med.2022, 17(1):66.
  • Evid Based Complement Alternat Med.2015, 2015:165457
  • Front Pharmacol.2019, 10:1025
  • Molecules.2019, 24(19):E3417
  • Int J Mol Sci.2018, 19(9):E2681
  • Appl. Sci. 2021, 11(22), 10552
  • Comparative Clinical Pathology 2021, 30:961-971.
  • J Agric Food Chem.2020, 68(51):15164-15175
  • Asian Journal of Chemistry2014, 26(22):7811-7816
  • Phytomedicine.2024, 129:155645.
  • Front Pharmacol.2021, 12:615157.
  • Food Res Int.2019, 123:125-134
  • Int J Mol Sci.2023, 24(22):16465.
  • Allergol Immunopathol (Madr).2022, 1;50(4):23-30.
  • Nutr Res Pract.2023, 17(4):670-681.
  • Aquaculture2017, 481:94-102
  • J Basic Clin Physiol Pharmacol.2016, 27(1):1-8
  • Environ Toxicol.2024, tox.24246
  • Phytomedicine.2019, 62:152962
  • Proc Biol Sci.2024, 291(2015):20232578.
  • Process Biochemistry2019, 85:106-115
  • ...
  • 生物活性
    Description: Curzerenone holds great promise for use in chemopreventive and chemotherapeutic strategies, it has slightly effective against E. coli (IZ = 10.8 ± 0.52).
    Targets: Caspase | Antifection
    In vitro:
    Pharmacognosy Res. 2012 Apr;4(2):80-4.
    Antioxidant and antibacterial activities of the leaf essential oil and its constituents furanodienone and curzerenone from Lindera pulcherrima (Nees.) Benth. ex hook. f.[Pubmed: 22518079]
    Lindera pulcherrima (Nees.) Benth. ex Hook. f. (Family: Lauraceae), an evergreen shrub, is an important medicinal plant distributed in temperate Himalayan regions. The leaves and bark are used as spice in cold, fever, and cough.
    METHODS AND RESULTS:
    In this study, the terpenoid composition, antioxidant, and antibacterial activities of the leaf essential oil and its major constituents are being analyzed.
    CONCLUSIONS:
    The in vitro antioxidant activity showed a potent free radical scavenging activity for the essential oil as evidenced by a low IC(50) value for DPPH radical followed by furanodienone (0.087 ± 0.03 and 1.164 ± 0.58 mg/ml respectively) and the inhibition of lipid peroxidation for the oil and furanodienone also followed the same order (IC(50) 0.74 ± 0.13 and 2.12 ± 0.49 mg/ml, respectively). The oil and the constituents were also tested against three Gram negative (Escherichia coli, Salmonella enterica enterica, and (Pasturella multocida) and one Gram positive (Staphylococcus aureus) bacteria. The essential oil was effective against S. aureus (IZ = 19.0 ± 0.34; MIC 3.90 μl/ml) while furanodienone showed potent activity against E. coli and S. enterica enterica (IZ = 18.0 ± 0.14 and 16.0 ± 0.10 respectively). On the other hand, curzerenone was found to be slightly effective against E. coli (IZ = 10.8 ± 0.52). The MIC value of the essential oil was least against S. aureus (MIC = 3.90 μl/ml) and that of furanodienone against E. coli (MIC = 3.90 μl/ml).
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.3422 mL 21.7108 mL 43.4216 mL 86.8432 mL 108.5541 mL
    5 mM 0.8684 mL 4.3422 mL 8.6843 mL 17.3686 mL 21.7108 mL
    10 mM 0.4342 mL 2.1711 mL 4.3422 mL 8.6843 mL 10.8554 mL
    50 mM 0.0868 mL 0.4342 mL 0.8684 mL 1.7369 mL 2.1711 mL
    100 mM 0.0434 mL 0.2171 mL 0.4342 mL 0.8684 mL 1.0855 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    异乌药内酯; Isolinderalactone CFN99762 957-66-4 C15H16O3 = 244.29 10mg QQ客服:3257982914
    苍术酮; Atractylone CFN92066 6989-21-5 C15H20O = 216.3 5mg QQ客服:215959384
    乌药醇; Linderene CFN90639 26146-27-0 C15H18O2 = 230.3 10mg QQ客服:215959384
    乌药醇乙酸酯; Linderene acetate CFN91930 26146-28-1 C17H20O3 = 272.34 5mg QQ客服:1457312923
    Strychnistenolide; Strychnistenolide CFN91933 332372-09-5 C15H18O4 = 262.30 5mg QQ客服:1457312923
    8beta,9alpha-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide; 8beta,9alpha-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide CFN91948 956707-04-3 C15H18O4 = 262.30 5mg QQ客服:2056216494
    姜黄醇酮; Curcolone CFN92651 17015-43-9 C15H18O3 = 246.3 5mg QQ客服:2159513211
    Zedoarofuran; Zedoarofuran CFN92619 213833-34-2 C15H20O4 = 264.3 5mg QQ客服:1457312923
    Curcolonol; Curcolonol CFN92650 217817-09-9 C15H20O4 = 264.3 5mg QQ客服:215959384
    1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane; 1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane CFN89321 59742-11-9 C19H24O5 = 332.39 5mg QQ客服:1457312923

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