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  • Chrysothol

    Chrysothol

    Chrysothol
    产品编号 CFN97477
    CAS编号 911714-91-5
    分子式 = 分子量 C15H26O2 = 238.4
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Sesquiterpenoids
    植物来源 The rhizomes of Acorus calamus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Chrysothol CFN97477 911714-91-5 1mg QQ客服:2159513211
    Chrysothol CFN97477 911714-91-5 5mg QQ客服:2159513211
    Chrysothol CFN97477 911714-91-5 10mg QQ客服:2159513211
    Chrysothol CFN97477 911714-91-5 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Osmania University (India)
  • University of Lodz (Poland)
  • Universidade de Franca (Brazil)
  • Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
  • University of Mysore (India)
  • Universitas islam negeri Jakarta (Indonesia)
  • Sant Gadge Baba Amravati University (India)
  • Medical University of Gdansk (Poland)
  • Max-Planck-Insitut (Germany)
  • Nanjing University of Chinese Medicine (China)
  • Universidade Federal de Santa Catarina (Brazil)
  • Universidad de Ciencias y Artes de Chiapas (Mexico)
  • Indian Institute of Science (India)
  • Srinakharinwirot University (Thailand)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Evid-Based Compl Alt2020, 7202519:13
  • J.Food Processing & Preservation2022, jfpp.16666
  • Evid Based Complement Alternat Med.2018, 2018:1073509
  • Onco Targets Ther.2017, 10:3467-3474
  • International Food Research Journal2018, 25(6):2560-2571
  • Saf Health Work.2019, 10(2):196-204
  • Tissue Cell.2022, 75:101728.
  • J Clin Med.2019, 8(10):E1664
  • Life Sci.2021, 270:119074.
  • Applied Biological Chemistry2022, 65(12)
  • Biomedicines.2021, 9(8):954.
  • J Pharmaceutical Research Int.2021, 33(41A):275-284.
  • University of Limpopo2016, 1777
  • J Chromatogr B Analyt Technol Biomed Life Sci. 2017, 1064:115-123
  • Toxicol Appl Pharmacol.2022, 434:115815.
  • Chem Biol Interact.2020, 328:109200.
  • Biochem Biophys Res Commun.2018, 505(1):261-266
  • Food Chem.2020, 313:126079
  • J Appl Toxicol.2020, 40(7):965-978.
  • Naunyn Schmiedebergs Arch Pharmacol.2017, 390(10):1073-1083
  • Plants (Basel).2020, 9(11):1422.
  • Cell Physiol Biochem.2019, 52(6):1255-1266
  • J Food Composition and Analysis2022, 104417.
  • ...
  • 生物活性
    Description: Chrysothol shows strong antimicrobial activities (MICs=50-100 ug/ml) against enterobacteria E. coli and S. enteritidis. It also shows anti-cancer activity against human breast cancer cells.
    Targets: Antifection
    In vitro:
    Pancreatology, 2006 ,6 (3) :175-9.
    Belgian Pancreatic Club Session at the 18th Belgian Week of Gastroenterology[Reference: WebLink]

    METHODS AND RESULTS:
    Fractions from the petroleum extracts showed strong antimicrobial activity, against Escherichia coli ATCC 25922, E. coli -LM 1 , E. coli -LM 2 , and Salmonella enteritidis -MI, with MICs values between 31.2 and 125μg/ml. The bioassay-guided fractionation of the petroleum ether extracts led to the isolation of nine terpenes: azorellolide ( 1 ), mulinol ( 2 ), stachytriol ( 3 ),1α,10β,4β,5α-diepoxy-7β-germacran-6β-ol ( 4 ), 1β,10α,4β,5α-diepoxy-7β-germacran-6β-ol ( 5 ), 1,2,3,3α,4,5,6,7,8,8α-decahydro-7-(1-hydroxy-1-methylethyl)-1,4-dimethylazulene-3α,8α-diol ( 6 ), madreporanone ( 7 ), yaretol ( 8 ) and chrysotol or 6β,10β-epoxy-4α-hydroxyguaiane ( 9 ). Compounds 3 , 5 , 6 and 9 are reported here for the first time from A. cryptantha . Their structures and relative configurations have been determinated by means 1D and 2D NMR techniques.
    CONCLUSIONS:
    Chrysothol ( 9 ), madreporanone ( 7 ), and stachytriol ( 3 ) showed strong antimicrobial activities (MICs=50–100μg/ml) against enterobacteria E. coli and S. enteritidis . The antibacterial activity found for some of the isolated compounds supports least in part, the commercial exploited of this species to treat food-borne illnesses associated with Gram negative pathogenic bacteria.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.1946 mL 20.9732 mL 41.9463 mL 83.8926 mL 104.8658 mL
    5 mM 0.8389 mL 4.1946 mL 8.3893 mL 16.7785 mL 20.9732 mL
    10 mM 0.4195 mL 2.0973 mL 4.1946 mL 8.3893 mL 10.4866 mL
    50 mM 0.0839 mL 0.4195 mL 0.8389 mL 1.6779 mL 2.0973 mL
    100 mM 0.0419 mL 0.2097 mL 0.4195 mL 0.8389 mL 1.0487 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Teuclatriol; Teuclatriol CFN99634 152110-17-3 C15H28O3 = 256.4 5mg QQ客服:1457312923
    苍术苷A; Atractyloside A CFN98560 126054-77-1 C21H36O10 = 448.5 20mg QQ客服:2056216494
    Isonardoperoxide; Isonardoperoxide CFN89350 205248-65-3 C15H22O4 = 266.33 5mg QQ客服:3257982914
    Orobanone; Orobanone CFN92654 78916-35-5 C15H20O = 216.3 5mg QQ客服:3257982914
    Zedoarondiol; Zedoarondiol CFN92652 98644-24-7 C15H24O3 = 252.4 5mg QQ客服:215959384
    异原莪述烯醇; Isoprocurcumenol CFN92620 102130-90-5 C15H22O2 = 234.3 5mg QQ客服:1413575084
    原莪术烯醇; Procurcumenol CFN92647 21698-40-8 C15H22O2 = 234.3 5mg QQ客服:1457312923
    表莪述烯醇; Epiprocurcumenol CFN91614 127214-97-5 C15H22O2 = 234.33 5mg QQ客服:215959384
    Aerugidiol; Aerugidiol CFN92621 116425-35-5 C15H22O3 = 250.3 5mg QQ客服:2159513211
    新原莪述烯醇; Neoprocurcumenol CFN92789 102130-91-6 C15H22O2 = 234.3 5mg QQ客服:2056216494

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