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  • Chrysothol

    Chrysothol

    Chrysothol
    产品编号 CFN97477
    CAS编号 911714-91-5
    分子式 = 分子量 C15H26O2 = 238.4
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Sesquiterpenoids
    植物来源 The rhizomes of Acorus calamus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Chrysothol CFN97477 911714-91-5 1mg QQ客服:1457312923
    Chrysothol CFN97477 911714-91-5 5mg QQ客服:1457312923
    Chrysothol CFN97477 911714-91-5 10mg QQ客服:1457312923
    Chrysothol CFN97477 911714-91-5 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universita' Degli Studi Di Cagliari (Italy)
  • University of Toulouse (France)
  • University of Melbourne (Australia)
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • National Chung Hsing University (Taiwan)
  • Weizmann Institute of Science (Israel)
  • Kyoto University (Japan)
  • Medical University of Gdansk (Poland)
  • University of Stirling (United Kingdom)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • Harvard University (USA)
  • Donald Danforth Plant Science Center (USA)
  • Copenhagen University (Denmark)
  • University of Illinois (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J of Applied Pharmaceutical Science2020, 10(1):077-082
  • Appl. Sci. 2021, 11(23),11099.
  • Aquaculture2017, 481:94-102
  • Clin Transl Med.2021, 11(5):e392.
  • Applied Biological Chemistry 2022, 65,5(2022).
  • Applied Biological Chemistry2023, 66(58):112.
  • Pharmaceutics.2022, 14(12):2765.
  • Oncotarget.2016, 8(51):88386-88400
  • J Appl Biol Chem2022, 65:343−348.
  • Applied Biological Chemistry2020, 63:33(2020)
  • VNU Journal of Science: Med.& Pharm. Sci.2022, 38(2):2588-1132.
  • Horticulture Research2023, uhad259
  • Planta Med.2019, 85(3):217-224
  • Phytomedicine.2019, 58:152893
  • Mol Cell.2017, 68(4):673-685
  • Exp Ther Med.2019, 18(6):4388-4396
  • Anal Chim Acta.2021, 1180:338874.
  • Toxins (Basel).2021, 13(12):898.
  • Journal of Plant Growth Regulation2022, 10705-2.
  • Phytomedicine.2018, 41:62-66
  • J Pharm Biomed Anal.2023, 234:115570.
  • Processes2021, 9(1), 153.
  • Biosci Biotechnol Biochem.2021, 85(10):2153-2160.
  • ...
  • 生物活性
    Description: Chrysothol shows strong antimicrobial activities (MICs=50-100 ug/ml) against enterobacteria E. coli and S. enteritidis. It also shows anti-cancer activity against human breast cancer cells.
    Targets: Antifection
    In vitro:
    Pancreatology, 2006 ,6 (3) :175-9.
    Belgian Pancreatic Club Session at the 18th Belgian Week of Gastroenterology[Reference: WebLink]

    METHODS AND RESULTS:
    Fractions from the petroleum extracts showed strong antimicrobial activity, against Escherichia coli ATCC 25922, E. coli -LM 1 , E. coli -LM 2 , and Salmonella enteritidis -MI, with MICs values between 31.2 and 125μg/ml. The bioassay-guided fractionation of the petroleum ether extracts led to the isolation of nine terpenes: azorellolide ( 1 ), mulinol ( 2 ), stachytriol ( 3 ),1α,10β,4β,5α-diepoxy-7β-germacran-6β-ol ( 4 ), 1β,10α,4β,5α-diepoxy-7β-germacran-6β-ol ( 5 ), 1,2,3,3α,4,5,6,7,8,8α-decahydro-7-(1-hydroxy-1-methylethyl)-1,4-dimethylazulene-3α,8α-diol ( 6 ), madreporanone ( 7 ), yaretol ( 8 ) and chrysotol or 6β,10β-epoxy-4α-hydroxyguaiane ( 9 ). Compounds 3 , 5 , 6 and 9 are reported here for the first time from A. cryptantha . Their structures and relative configurations have been determinated by means 1D and 2D NMR techniques.
    CONCLUSIONS:
    Chrysothol ( 9 ), madreporanone ( 7 ), and stachytriol ( 3 ) showed strong antimicrobial activities (MICs=50–100μg/ml) against enterobacteria E. coli and S. enteritidis . The antibacterial activity found for some of the isolated compounds supports least in part, the commercial exploited of this species to treat food-borne illnesses associated with Gram negative pathogenic bacteria.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.1946 mL 20.9732 mL 41.9463 mL 83.8926 mL 104.8658 mL
    5 mM 0.8389 mL 4.1946 mL 8.3893 mL 16.7785 mL 20.9732 mL
    10 mM 0.4195 mL 2.0973 mL 4.1946 mL 8.3893 mL 10.4866 mL
    50 mM 0.0839 mL 0.4195 mL 0.8389 mL 1.6779 mL 2.0973 mL
    100 mM 0.0419 mL 0.2097 mL 0.4195 mL 0.8389 mL 1.0487 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    异莪术醇; Isocurcumenol CFN92618 24063-71-6 C15H22O2 = 234.3 20mg QQ客服:3257982914
    莪术醇; 姜黄醇; Curcumol CFN99187 4871-97-0 C15H24O2 = 236.35 20mg QQ客服:2056216494
    4beta,12-dihydroxyguaian-6,10-diene; 4beta,12-dihydroxyguaian-6,10-diene CFN90947 461644-90-6 C15H24O2 = 236.34 5mg QQ客服:215959384
    Chrysothol; Chrysothol CFN97477 911714-91-5 C15H26O2 = 238.4 5mg QQ客服:1413575084
    泽泻醇; Alismol CFN97446 87827-55-2 C15H24O = 220.4 10mg QQ客服:3257982914
    环氧泽泻烯; Alismoxide CFN99775 87701-68-6 C15H26O2 = 238.37 20mg QQ客服:3257982914
    愈创醇; Guaiol CFN96326 489-86-1 C15H26O = 222.4 5mg QQ客服:2056216494
    Teuclatriol; Teuclatriol CFN99634 152110-17-3 C15H28O3 = 256.4 5mg QQ客服:215959384
    苍术苷A; Atractyloside A CFN98560 126054-77-1 C21H36O10 = 448.5 20mg QQ客服:1457312923
    Isonardoperoxide; Isonardoperoxide CFN89350 205248-65-3 C15H22O4 = 266.33 5mg QQ客服:2159513211

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