| In vitro: |
| European Food Research & Technology, 2004 , 218 (3) :253-261. | | Antioxidant activity of Geranium macrorrhizum.[Reference: WebLink] | The composition of radical-scavenging compounds from Geranium macrorrhizum leaves was analyzed and the antioxidative activities of various extracts was determined.
METHODS AND RESULTS:
Seven compounds, namely gallic acid, ellagic acid, 4-Galloylquinic acid, the flavonoid quercetin and three of its glycosides, quercetin-3--glucopyranoside, quercetin-3--galactopyranoside and quercetin-4--glucopyranoside were isolated and identified in the various fractions. The radical-scavenging activity of the isolated compounds was measured using DPPH and ABTS+ scavenging assays and compared with the activity of rosmarinic acid. Quercetin-3-glucopyranoside and quercetin-3-galactopyranoside showed the highest antioxidative capacities. Antioxidative activities of all plant fractions were assessed by model system tests (superoxide anion and hydrogen peroxide scavenging) and by oxidation tests (-carotene bleaching, peroxide value, UV absorbance and headspace-gas chromatography hexanal determination).
CONCLUSIONS:
The ethanol-butanol fraction of the plant possessed the highest activity in most of the tests. |
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