(3beta,11alpha,12alpha,13alpha)-11,12-环氧-13-甲基-27-去甲齐墩果-14-烯-3-醇十六烷酸酯

11alpha,12alpha-Oxidotaraxerol palmitate

	产品编号	CFN96827
	CAS编号	495389-95-2
	分子式 = 分子量	C₄₆H₇₈O₃ = 679.11
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Triterpenoids
	植物来源	The herbs of Cirsium setosum (Willd.) MB.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
(3beta,11alpha,12alpha,13alpha)-11,12-环氧-13-甲基-27-去甲齐墩果-14-烯-3-醇十六烷酸酯	CFN96827	495389-95-2	1mg	QQ客服：215959384
(3beta,11alpha,12alpha,13alpha)-11,12-环氧-13-甲基-27-去甲齐墩果-14-烯-3-醇十六烷酸酯	CFN96827	495389-95-2	5mg	QQ客服：215959384
(3beta,11alpha,12alpha,13alpha)-11,12-环氧-13-甲基-27-去甲齐墩果-14-烯-3-醇十六烷酸酯	CFN96827	495389-95-2	10mg	QQ客服：215959384
(3beta,11alpha,12alpha,13alpha)-11,12-环氧-13-甲基-27-去甲齐墩果-14-烯-3-醇十六烷酸酯	CFN96827	495389-95-2	20mg	QQ客服：215959384

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Sant Gadge Baba Amravati University (India)

Instytut Nawozów Sztucznych w Pu?awach (Poland)

Universite Libre de Bruxelles (Belgium)

University of British Columbia (Canada)

University of Padjajaran (Indonesia)

Julius Kühn-Institut (Germany)

Leibniz Institute of Plant Biochemistry (Germany)

Helmholtz Zentrum München (Germany)

Sapienza University of Rome (Italy)

University of Bonn (Germany)

University of Indonesia (Indonesia)

Medical University of Gdansk (Poland)

University of Wuerzburg (Germany)

University of East Anglia (United Kingdom)

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Description:

11alpha,12alpha-Oxidotaraxerol palmitate shows selective cytotoxicity against HCT-8, Bel-7402, BGC-823, A549 and A2780.

In vitro:

Journal of Chinese Institute of Food Science & Technology,2014,14(3):196-204.

Isolation, purification, elucidation and cytotoxicity activity on oxidotaraxerone and oxidationtaraxerol of Cirsium setosum (Willd.) MB[Reference: WebLink]

To investigate chemical constituents contained in cytotoxic petroleum ether-soluble portion from the ethanol extracts of Cirsium setosum (Willd.) MB, and evaluate their cytotoxic activity in vitro.
METHODS AND RESULTS:
The constituents were separated and purified by various chromatographic methods including silica gel and Sephadex LH-20, and their structures were elucidated by spectroscopic methods including NMR, MS methods and comparison with literature. Three oxidotaraxerane triterpenoids were isolated from the petroleum ether fraction of ethanolic extract of Cirsium setosum, and determined as 11α, 12α-oxidotaraxerone, 11α, 12α-oxidotaraxerol and 11alpha,12alpha-Oxidotaraxerol palmitate.
CONCLUSIONS:
To the best of our knowledge, this is the first report showing the presence of all the compounds in the genus Cirsium. In the in vitro assays, three compounds showed selective cytotoxicity against HCT-8, Bel-7402, BGC-823, A549 and A2780.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
beta-香树脂醇乙酸酯; beta-Amyrin acetate	CFN99679	1616-93-9	C₃₂H₅₂O₂ = 468.8	5mg	QQ客服：3257982914
beta-软脂酸香树精酯; beta-Amyrin palmitate	CFN97009	5973-06-8	C₄₆H₈₀O₂ = 665.1	5mg	QQ客服：2159513211
beta-白檀酮; beta-Amyrone	CFN97099	638-97-1	C₃₀H₄₈O = 424.7	5mg	QQ客服：215959384
9(11),12-齐墩果二烯-3beta-醇; 9(11),12-Oleanadien-3-ol	CFN97528	94530-87-7	C₃₀H₄₈O = 424.7	5mg	QQ客服：215959384
齐墩果-12-烯-3b,6b-二醇; 12-Oleanene-3,6-diol	CFN94009	41498-79-7	C₃₀H₅₀O₂ = 442.72	5 mg	QQ客服：2159513211
曼陀罗萜醇酮; Daturaolone	CFN94010	41498-80-0	C₃₀H₄₈O₂ = 440.71	5 mg	QQ客服：2056216494
黑果茜草萜 B ; Rubiprasin B	CFN96835	125263-66-3	C₃₂H₅₂O₄ = 500.76	5mg	QQ客服：3257982914
黑果茜草萜 A ; Rubiprasin A	CFN96836	125263-65-2	C₃₂H₅₂O₅ = 516.76	5mg	QQ客服：2056216494
13(18)-齐墩果烯-3-醇，Α-香树素; 13(18)-Oleanen-3-ol	CFN98801	508-04-3	C₃₀H₅₀O = 426.7	5mg	QQ客服：2056216494
乙酸-delta-香树精酯; delta-Amyrin acetate	CFN98820	51361-60-5	C₃₂H₅₂O₂ = 468.8	5mg	QQ客服：215959384

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.4725 mL	7.3626 mL	14.7252 mL	29.4503 mL	36.8129 mL
5 mM	0.2945 mL	1.4725 mL	2.945 mL	5.8901 mL	7.3626 mL
10 mM	0.1473 mL	0.7363 mL	1.4725 mL	2.945 mL	3.6813 mL
50 mM	0.0295 mL	0.1473 mL	0.2945 mL	0.589 mL	0.7363 mL
100 mM	0.0147 mL	0.0736 mL	0.1473 mL	0.2945 mL	0.3681 mL

(3beta,11alpha,12alpha,13alpha)-11,12-环氧-13-甲基-27-去甲齐墩果-14-烯-3-醇十六烷酸酯

11alpha,12alpha-Oxidotaraxerol palmitate

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