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  • 西伯利亚远志糖A6

    Sibiricose A6

    西伯利亚远志糖A6
    产品编号 CFN90646
    CAS编号 241125-75-7
    分子式 = 分子量 C23H32O15 = 548.5
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenylpropanoids
    植物来源 The roots of Polygala tenuifolia.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    西伯利亚远志糖A6 CFN90646 241125-75-7 10mg QQ客服:2159513211
    西伯利亚远志糖A6 CFN90646 241125-75-7 20mg QQ客服:2159513211
    西伯利亚远志糖A6 CFN90646 241125-75-7 50mg QQ客服:2159513211
    西伯利亚远志糖A6 CFN90646 241125-75-7 100mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Heinrich-Heine-University Düsseldorf (Germany)
  • Texas A&M University (USA)
  • Universidad de Antioquia (Colombia)
  • Wageningen University (Netherlands)
  • National Cancer Institute (USA)
  • Institute of Chinese Materia Medica (China)
  • Aarhus University (Denmark)
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  • Massachusetts General Hospital (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Faculty of Chem. & Nat. Resource Eng.2014, 62
  • Am J Chin Med.2015, 30:1-22
  • Jour. of Stored Pro & Postharvest Res.2016, 7(3):32-36
  • Current Pharmaceutical Analysis2017, 13(5)
  • J. of The Korean Society of Food Culture2017, 144-149
  • Int J Mol Sci.2017, 18(12)
  • J Ethnopharmacol.2017, 198:205-213
  • Plant Cell Tiss Org2017, 479-486
  • PLoS One.2018, 13(4):e0195642
  • Neuropharmacology.2018, 131:68-82
  • Food Chem.2018, 252:207-214
  • Sci Rep.2018, 8:9267
  • J of Health Science and Alternative Medicine2019, 1(1)
  • Analytical methods2019, 11(6)
  • Front Aging Neurosci.2019, 11:230
  • Exp Biol Med (Maywood).2019, 244(16):1463-1474
  • Environ Toxicol.2019, 34(4):513-520.
  • Anal Sci.2019, 35(12):1317-1325
  • J Food Sci Technol.2019, 56(5):2712-2720
  • Phytomedicine.2019, 67:153159
  • Plant Foods Hum Nutr.2020, 10.1007
  • Nutrients2020, 12(2):488
  • J Ethnopharmacol.2020, 249:112396
  • ...
  • 生物活性
    Description: Sibiricose A6 displays antidepressant-like action, it may prevent or relieve depression; it also shows potent antioxidant activity.
    In vitro:
    《China Journal of Chinese Materia Medica》 2008-11
    Study on antidepressant components of sucrose ester from Polygala tenuifolia[Reference: WebLink]
    To investigate the antidepressant components of Polygala tenuifolia.
    METHODS AND RESULTS:
    The chromatographic method was used to isolate and purify the chemical constituents,their structures were identified by spectral analysis,MTT method was applied to investigate their cytotoxic activities. Nine compounds were isolated from the roots of P.tenuifolia.Their structures were identified as sibiricose A1(1),sibiricose A5(2),tenuifoliside A(3) and 3′,6-disinapoyl sucrose(4),sibiricose A6(5),3,4,5-trimethoxycinnamate(6),polygalaxanthone Ⅲ(7),tenuifolioses A(8),tenuifolioses H(9) and some compounds' activities to PC12 were observed.
    CONCLUSIONS:
    Compound1 was isolated from this plant for the first time.Compounds 2,3 could protect PC12 cells damage induced by P.tenuifolia.
    Talanta. 2015 Nov 1;144:830-5.
    Indirect identification of antioxidants in Polygalae Radix through their reaction with 2,2-diphenyl-1-picrylhydrazyl and subsequent HPLC-ESI-Q-TOF-MS/MS.[Pubmed: 26452897]
    A rapid and efficient method for the identification of antioxidants in the traditional Chinese medicine Polygalae Radix (PR) by HPLC-ESI-Q-TOF-MS/MS is described.
    METHODS AND RESULTS:
    The method is based on the hypothesis that upon reaction of antioxidants with 1,1-diphenyl-2-picrylhydrazyl (DPPH), the peak areas of compounds with potential antioxidant activities in the HPLC chromatogram will be significantly reduced in comparison to the untreated sample. The identity confirmation was achieved by Q-TOF-MS/MS technique. With this method, eight components were proposed possessing potent antioxidant activity. They were identified as sibiricose A5, sibiricose A6, sucrose monoester, polygalaxanthone III, tenuifoliside B, 3',6-disinapoylsucrose (DISS), sucrose diester, tenuifoliside C, respectively. DISS was proposed to be the most potent one. The antioxidant activity of DISS was evaluated by DPPH, ABTS radical scavenging assay and ferric-reducing antioxidant power (FRAP) assay in vitro. Vitamin C (Vc) was used as positive control substance. DISS showed moderate DPPH (DISS's IC50 value was 1024.17 μg/mL, Vc's was 294.68 μg/mL) and ABTS (IC50 324.13 μg/mL, Vc's was 117.50 μg/mL) free radical scavenging capacity and ferric-reducing antioxidant power.
    CONCLUSIONS:
    DISS can be used as a new source of natural antioxidant in foods and cosmetics.
    In vivo:
    Molecules. 2011 Jun 29;16(7):5507-13.
    Absorbable phenylpropenoyl sucroses from Polygala tenuifolia.[Pubmed: 21716172]

    METHODS AND RESULTS:
    Three phenylpropenoyl sucroses--Sibiricose A5, Sibiricose A6 and 3',6-disinapoyl sucrose--were isolated from the 30% EtOH extract of Polygala tenuifolia, which displayed antidepressant-like action.
    CONCLUSIONS:
    HPLC analysis indicated that the three phenylpropenoyl sucroses could be absorbed into serum. From the serum pharmacochemistry point of view, these three phenylpropenoyl sucroses might prevent or relieve depression.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8232 mL 9.1158 mL 18.2315 mL 36.4631 mL 45.5789 mL
    5 mM 0.3646 mL 1.8232 mL 3.6463 mL 7.2926 mL 9.1158 mL
    10 mM 0.1823 mL 0.9116 mL 1.8232 mL 3.6463 mL 4.5579 mL
    50 mM 0.0365 mL 0.1823 mL 0.3646 mL 0.7293 mL 0.9116 mL
    100 mM 0.0182 mL 0.0912 mL 0.1823 mL 0.3646 mL 0.4558 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Teupolioside; Teupolioside CFN70272 143617-02-1 C35H46O20 = 786.7 5mg QQ客服:3257982914
    6-O-(E)-咖啡酰基葡萄糖苷; 6-O-(E)-Caffeoylglucopyranose CFN95105 209797-79-5 C15H18O9 = 342.3 5mg QQ客服:2932563308
    6-O-阿魏酰葡萄糖; 6-O-Feruloylglucose CFN99431 137887-25-3 C16H20O9 = 356.3 5mg QQ客服:215959384
    6'-O-阿魏酰蔗糖; Arillatose B CFN99432 137941-45-8 C22H30O14 = 518.5 5mg QQ客服:1148253675
    西伯利亚远志糖A5; Sibiricose A5 CFN90645 107912-97-0 C22H30O14 = 518.5 20mg QQ客服:1413575084
    西伯利亚远志糖A6; Sibiricose A6 CFN90646 241125-75-7 C23H32O15 = 548.5 20mg QQ客服:3257982914
    6-O-咖啡酰基熊果甙; 6-O-Caffeoylarbutin CFN99427 136172-60-6 C21H22O10 = 434.4 5mg QQ客服:2932563308
    灯盏花苷 I; Erigeside I CFN96865 224824-74-2 C20H20O11 = 436.36 5mg QQ客服:3257982914
    木通苯乙醇苷B; Calceolarioside B CFN90647 105471-98-5 C23H26O11 = 478.45 20mg QQ客服:2159513211
    木通苯乙醇苷A; Calceolarioside A CFN98522 84744-28-5 C23H26O11 = 478.44 5mg QQ客服:1148253675

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