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  • 2'-乙酰基金石蚕苷

    Brandioside

    2'-乙酰基金石蚕苷
    产品编号 CFN90882
    CAS编号 133393-81-4
    分子式 = 分子量 C37H48O20 = 812.8
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenylpropanoids
    植物来源 The herbs of Verbena officinalis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    2'-乙酰基金石蚕苷 CFN90882 133393-81-4 1mg QQ客服:2159513211
    2'-乙酰基金石蚕苷 CFN90882 133393-81-4 5mg QQ客服:2159513211
    2'-乙酰基金石蚕苷 CFN90882 133393-81-4 10mg QQ客服:2159513211
    2'-乙酰基金石蚕苷 CFN90882 133393-81-4 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • FORTH-IMBB (Greece)
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  • Mendel University in Brno (Czech Republic)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Phytomedicine.2015, 22(4):498-503
  • Inflammation2015, 38(1):445-55
  • Nat Plants.2016, 3:16205
  • Eur J Pharm Sci.2016, 94:33-45
  • African J. Agricultural Research 2017, 12(13):1164-1168
  • Phytochemistry.2017, 141:162-170
  • J Sci Food Agric.2017, 97(5):1656-1662
  • Food Quality and Safety2018, 2:213-219
  • J Ethnopharmacol.2018, 210:88-94
  • Korean J of Medicinal Crop Science2018, 220-226
  • Molecules.2018, 23(3):E615
  • Biochem Biophys Res Commun.2018, 505(1):194-200
  • J Herbmed Pharmacol.2018, 7(4):280-286
  • Microb Pathog.2019, 131:128-134
  • Industrial Crops and Products2019, 140:111612
  • Plant Physiol Biochem.2019, 144:355-364
  • J Pharm Biomed Anal.2019, 164:119-127
  • Molecules.2019, 24(4):E744
  • J Ethnopharmacol.2019, 244:112074
  • Food Chem.2019, 275:746-753
  • Chin J Appl. Physiol.2019, 35(3):283-288
  • J of Ana. Chem.2019, 74(11):1113-1121
  • Biomedicine & Pharmacotherapy2020, 125:109950
  • ...
  • 生物活性
    Description: Brandioside shows strong antioxidant, and neuroprotective effects, it significantly attenuates glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 microM; it exhibits significant inhibition of advanced glycation end product formation with the IC50 value of 4.6-25.7 uM. Brandioside shows inhibition of smooth muscle cell proliferation, indicates that it may have preventative effects on arteriosclerosis.
    Targets: ROS
    In vitro:
    Planta Med. 2013 Dec;79(18):1705-9.
    Caffeoylated phenylpropanoid glycosides from Brandisia hancei inhibit advanced glycation end product formation and aldose reductase in vitro and vessel dilation in larval zebrafish in vivo.[Pubmed: 24288293 ]
    In our continuing efforts to identify effective naturally sourced agents for diabetic complications, five caffeoylated phenylpropanoid glycosides, acteoside (1), isoacteoside (2), poliumoside (3), brandioside (4), and pheliposide (5) were isolated from the 80% EtOH extract of Brandisia hancei stems and leaves.
    METHODS AND RESULTS:
    These isolates (1-5) were subjected to an in vitro bioassay evaluating their inhibitory activity on advanced glycation end product formation and rat lens aldose reductase activity. All tested compounds exhibited significant inhibition of advanced glycation end product formation with IC50 values of 4.6-25.7 µM, compared with those of aminoguanidine (IC50=1,056 µM) and quercetin (IC50=28.4 µM) as positive controls. In the rat lens aldose reductase assay, acteoside, isoacteoside, and poliumoside exhibited greater inhibitory effects on rat lens aldose reductase with IC50 values of 0.83, 0.83, and 0.85 µM, respectively, than those of the positive controls, 3,3-tetramethyleneglutaric acid (IC50=4.03 µM) and quercetin (IC50=7.2 µM). In addition, the effect of acteoside on the dilation of hyaloid-retinal vessels induced by high glucose in larval zebrafish was investigated.
    CONCLUSIONS:
    Acteoside reduced the diameters of high glucose-induced hyaloid-retinal vessels by 69% at 10 µM and 81% at 20 µM, compared to the high glucose-treated control group. These results suggest that B. hancei and its active components might be beneficial in the treatment and prevention of diabetic vascular complications.
    Planta Med. 2005 Aug;71(8):778-80.
    In vitro neuroprotective activities of phenylethanoid glycosides from Callicarpa dichotoma.[Pubmed: 16142646 ]

    METHODS AND RESULTS:
    Ten phenylethanoid glycosides, forsythoside B, acteoside, 2'-acetylacteoside, poliumoside, brandioside, echinacoside, isoacteoside, cistanoside H and E-tubuloside E as well as a new compound, Z-tubuloside E, were isolated from the n-BuOH fraction of Callicarpa dichotoma Raeuschel (Verbenaceae) by bioactivity-guided fractionation using glutamate-injured primary cultures of rat cortical cells as a screening system.
    CONCLUSIONS:
    These phenylethanoid glycosides significantly attenuated glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 microM.
    J Ethnopharmacol. 2000 Aug;71(3):483-6.
    Antioxidant activity of phenylethanoid glycosides from Brandisia hancei.[Pubmed: 10940587]
    Brandisia hancei is a medicinal herb in China.
    METHODS AND RESULTS:
    The ethanol extract of this plant and four phenylethanoid glycosides, acteoside (1), 2'-acetylacteoside (2), poliumoside (3) and brandioside (4), isolated from it were shown to have inhibitory effects on free radical-induced hemolysis of red blood cells and free radical scavenging activities in vitro. Brandioside (4) and poliumoside (3) showed stronger antioxidant effect than acteoside (1), 2'-acetylacteoside (2) and trolox.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.2303 mL 6.1516 mL 12.3031 mL 24.6063 mL 30.7579 mL
    5 mM 0.2461 mL 1.2303 mL 2.4606 mL 4.9213 mL 6.1516 mL
    10 mM 0.123 mL 0.6152 mL 1.2303 mL 2.4606 mL 3.0758 mL
    50 mM 0.0246 mL 0.123 mL 0.2461 mL 0.4921 mL 0.6152 mL
    100 mM 0.0123 mL 0.0615 mL 0.123 mL 0.2461 mL 0.3076 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    灯盏花苷 I; Erigeside I CFN96865 224824-74-2 C20H20O11 = 436.36 5mg QQ客服:1148253675
    木通苯乙醇苷B; Calceolarioside B CFN90647 105471-98-5 C23H26O11 = 478.45 20mg QQ客服:3257982914
    木通苯乙醇苷A; Calceolarioside A CFN98522 84744-28-5 C23H26O11 = 478.44 5mg QQ客服:2932563308
    去鼠李糖地黄苷; Desrhamnosylmartynoside CFN89370 136055-64-6 C25H30O11 = 506.49 5mg QQ客服:1413575084
    连翘酯苷B; Forsythoside B CFN99715 81525-13-5 C34H44O19 = 756.70 20mg QQ客服:3257982914
    金石蚕苷; Poliumoside CFN99714 94079-81-9 C35H46O19 = 770.73 20mg QQ客服:3257982914
    2'-乙酰基金石蚕苷; Brandioside CFN90882 133393-81-4 C37H48O20 = 812.8 10mg QQ客服:1413575084
    松果菊苷; Echinacoside CFN98105 82854-37-3 C35H46O20 = 786.72 20mg QQ客服:1148253675
    2'-鼠李糖松果菊苷; 2'-Rhamnoechinacoside CFN95035 1422390-59-7 C41H56O24 = 932.9 10mg QQ客服:2932563308
    紫地黄甙C; Purpureaside C CFN93410 108648-07-3 C35H46O20 = 786.7 5mg QQ客服:1148253675

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