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  • 焦地黄苯乙醇甙B1

    Jionoside B1

    焦地黄苯乙醇甙B1
    产品编号 CFN90729
    CAS编号 120406-37-3
    分子式 = 分子量 C37H50O20 = 814.78
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Polyphenols
    植物来源 The roots of Rehmannia glutinosa
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    焦地黄苯乙醇甙B1 CFN90729 120406-37-3 1mg QQ客服:2056216494
    焦地黄苯乙醇甙B1 CFN90729 120406-37-3 5mg QQ客服:2056216494
    焦地黄苯乙醇甙B1 CFN90729 120406-37-3 10mg QQ客服:2056216494
    焦地黄苯乙醇甙B1 CFN90729 120406-37-3 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Wroclaw Medical University (Poland)
  • Siksha O Anusandhan University (India)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Research Unit Molecular Epigenetics (MEG) (Germany)
  • Almansora University (Egypt)
  • The Australian National University (Australia)
  • Leibniz Institute of Plant Biochemistry (Germany)
  • Universidad de Antioquia (Colombia)
  • Georgia Institute of Technology (USA)
  • Johannes Gutenberg University Mainz (JGU) (Germany)
  • Center for protein Engineering (CIP) (Belgium)
  • University of Maryland School of Medicine (USA)
  • Universidade Federal de Goias (UFG) (Brazil)
  • University of Toronto (Canada)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Neuropharmacology.2018, 131:68-82
  • Research on Crops.2017, 18(2)
  • J of the Korean Society of Cosmetics and Cosmetology2019, 225-231
  • Viruses2023, 15(6), 1377
  • Molecules.2021, 26(4):816.
  • J Appl Biol Chem2023, 66:455−461
  • Drug Des Devel Ther.2023, 17:2461-2479.
  • Auburn University2015, 1-58
  • Front Pharmacol.2019, 10:1226
  • Phytomedicine.2021, 83:153483.
  • Front Microbiol.2019, 10:2806
  • Phytomedicine.2019, 58:152893
  • J Nat Prod.2015, 78(6):1339-4
  • BioResources J.2020, 15(3).
  • J Pharmacol Sci.2021, 147(2):184-191.
  • Journal of Apicultural Research2021, 60(1)
  • Front Pharmacol.2021, 12:635510.
  • Appl. Sci.2020, 10(20), 7323.
  • Int J Mol Sci.2015, 16(8):18396-411
  • University of Guelph2021, 12.
  • Molecules.2021, 26(18):5665.
  • Molecules.2020, 25(11):2599.
  • Nutrients2020, 12(2):488
  • ...
  • 生物活性
    Description: Jionoside B1 has immunosuppressive activity, it shows the hepato-protective activity in the H2O2 induced liver injury experiments.Jionoside B1 exhibits the obvious inhibition against aldose reductase.
    In vitro:
    Chinese Traditional & Herbal Drugs, 2016, 47(11): 1830-3.
    Chemical constituents from whole plants of oehmannia chingii[Reference: WebLink]
    To investigate the chemical constituents of Rehmannia chingii.
    METHODS AND RESULTS:
    The compounds were isolated from an aqueous extract from the whole plants of R.chingii by a combination of various chromatographic techniques including column chromatography over silica gel and Sephadex LH-20 and reversed-phase HPLC.Their structures were identified by spectroscopic analysis including MS and NMR data. Seventeen compounds were isolated and identified as 8-methyloctahydrocyclopenta [c] pyran-1,3,6,8-tetraol(1),3,4-dihydroxy-phenethyl alcohol(2),3-methoxyl-4-hydroxyphenyl alcohol(3),phenylethyl-8-O-β-D-glucopyranoside(4),3,4-dihydroxy-β-phenethyl-O-α-L-rhamnopyranosyl-(1→3)-O-β-D-glucopyranoside(5),2-phenylethylO-β-D-xylopyranosyl-(1→6)-β-D-glucopyranoside(6),deacyl-martynoside(7),acteoside(8),isoacteoside(9),martynoside(10),isomartynoside(11),jionoside C(12),jionoside A1(13),Jionoside B1(14),3,4-dihydroxy-β-phenethyl-O-α-L-rhamnopyranosyl-(1→3)-O-β-D-galacopyranosyl-(1→6)-4-O-caffeoyl-β-D-glucopyranoside(15),cistanoside F(16),and isocistanoside F(17).
    CONCLUSIONS:
    Among the isolated seventeen compounds,compound 1 is a new compound named rehmachinin,and compounds 16-17 are isolated from the plants of Rehmannia Libosch.ex Fisch.et Mey.for the first time. In the preliminary assays,compounds 9,12,and 14-16 exhibit the obvious inhibition against aldose reductase.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.2273 mL 6.1366 mL 12.2733 mL 24.5465 mL 30.6831 mL
    5 mM 0.2455 mL 1.2273 mL 2.4547 mL 4.9093 mL 6.1366 mL
    10 mM 0.1227 mL 0.6137 mL 1.2273 mL 2.4547 mL 3.0683 mL
    50 mM 0.0245 mL 0.1227 mL 0.2455 mL 0.4909 mL 0.6137 mL
    100 mM 0.0123 mL 0.0614 mL 0.1227 mL 0.2455 mL 0.3068 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Clemomandshuricoside B; Clemomandshuricoside B CFN95302 905294-48-6 C22H30O13 = 502.2 10mg QQ客服:1413575084
    西伯利亚远志糖A5; Sibiricose A5 CFN90645 107912-97-0 C22H30O14 = 518.5 20mg QQ客服:2056216494
    西伯利亚远志糖A6; Sibiricose A6 CFN90646 241125-75-7 C23H32O15 = 548.5 20mg QQ客服:1457312923
    西伯利亚远志糖A1; Sibiricose A1 CFN91841 139726-40-2 C23H32O15 = 548.5 5mg QQ客服:215959384
    6-O-咖啡酰基熊果甙; 6-O-Caffeoylarbutin CFN99427 136172-60-6 C21H22O10 = 434.4 5mg QQ客服:3257982914
    灯盏花苷 I; Erigeside I CFN96865 224824-74-2 C20H20O11 = 436.36 5mg QQ客服:2056216494
    木通苯乙醇苷B; Calceolarioside B CFN90647 105471-98-5 C23H26O11 = 478.45 20mg QQ客服:215959384
    木通苯乙醇苷A; Calceolarioside A CFN98522 84744-28-5 C23H26O11 = 478.44 5mg QQ客服:3257982914
    去鼠李糖地黄苷; Desrhamnosylmartynoside CFN89370 136055-64-6 C25H30O11 = 506.49 5mg QQ客服:215959384
    管花肉苁蓉苷B1; Cistantubuloside B1 CFN95714 130009-44-8 C35H46O19 = 770.7 5mg QQ客服:1457312923

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