beta-鼠李素

beta-Rhamnocitrin

	产品编号	CFN92328
	CAS编号	90-19-7
	分子式 = 分子量	C₁₆H₁₂O₇ = 316.3
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Flavonoids
	植物来源	The branches of Rhamnus cathartica
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
beta-鼠李素	CFN92328	90-19-7	1mg	QQ客服：3257982914
beta-鼠李素	CFN92328	90-19-7	5mg	QQ客服：3257982914
beta-鼠李素	CFN92328	90-19-7	10mg	QQ客服：3257982914
beta-鼠李素	CFN92328	90-19-7	20mg	QQ客服：3257982914

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Uniwersytet Medyczny w ?odzi (Poland)

Copenhagen University (Denmark)

Universitas islam negeri Jakarta (Indonesia)

Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)

Univerzita Karlova v Praze (Czech Republic)

Korea Intitute of Science and Technology (KIST) (Korea)

Monash University Malaysia (Malaysia)

Universiti Malaysia Pahang (Malaysia)

Auburn University (USA)

Shanghai Institute of Organic Chemistry (China)

Universidad de La Salle (Mexico)

University of East Anglia (United Kingdom)

Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)

University of Wollongong (Australia)

More...

Description:

Beta-Rhamnocitrin is used as a 0.4% aq. soln. for photometric detn. of U (max 505 nm), Th, Fe.

In vivo:

Molecules . 2017 Aug 31;22(9):1441.

Evaluation of Rhamnetin as an Inhibitor of the Pharmacological Effect of Secretory Phospholipase A2[Pubmed: 28858248]

Abstract Rhamnetin (Rhm), 3-O-methylquercetin (3MQ), and Rhamnazin (Rhz) are methylated derivatives of quercetin commonly found in fruits and vegetables that possess antioxidant and anti-inflammatory properties. Phospholipase A2 (PLA2) displays several important roles during acute inflammation; therefore, this study aimed at investigating new compounds able to inhibit this enzyme, besides evaluating creatine kinase (CK) levels and citotoxicity. Methylated quercetins were compared with quercetin (Q) and were incubated with secretory PLA2 (sPLA2) from Bothrops jararacussu to determine their inhibitory activity. Cytotoxic studies were performed by using the J774 cell lineage incubated with quercertins. In vivo tests were performed with Swiss female mice to evaluate decreasing paw edema potential and compounds' CK levels. Structural modifications on sPLA2 were made with circular dichroism (CD). Despite Q and Rhz showing greater enzymatic inhibitory potential, high CK was observed. Rhm exhibited sPLA2 inhibitory potential, no toxicity and, remarkably, it decreased CK levels. The presence of 3OH on the C-ring of Rhm may contribute to both its anti-inflammatory and enzymatic inhibition of sPLA2, and the methylation of ring A may provide the increase in cell viability and low CK level induced by sPLA2. These results showed that Rhm can be a candidate as a natural compound for the development of new anti-inflammatory drugs. Keywords: Bothrops jararacussu; anti-inflammatory; methylated quercetins; phospholipase A2; rhamnetin.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
菠叶素; Spinacetin	CFN95194	3153-83-1	C₁₇H₁₄O₈ = 346.3	5mg	QQ客服：2056216494
棕鳞矢车菊黄酮素; Jaceidin	CFN99032	10173-01-0	C₁₈H₁₆O₈ = 360.3	5mg	QQ客服：2159513211
三乙酸棕鳞矢车菊黄酮素酯; Jaceidin triacetate	CFN99482	14397-69-4	C₂₄H₂₂O₁₁ = 486.4	5mg	QQ客服：1413575084
猫眼草黄素; Chrysosplenetin	CFN97026	603-56-5	C₁₉H₁₈O₈ = 374.4	20mg	QQ客服：2159513211
4',5,7-三羟基 3,3',6,8-四甲氧基黄酮 ; 4',5,7-Trihydroxy 3,3',6,8-tetramethoxyflavone	CFN70415	58130-91-9	C₁₉H₁₈O₉ = 390.3	5mg	QQ客服：215959384
3',4',7,8-四甲氧基黄酮; 3',4',7,8-Tetramethoxyflavone	CFN70432	65548-55-2	C₁₉H₁₈O₆ = 342.4	20mg	QQ客服：2159513211
4'-羟基-6,7,8,3'-四甲氧基黄酮醇; 4'-hydroxy-6,7,8,3'-tetramethoxyflavonol	CFN91846	1879030-01-9	C₁₉H₁₈O₈ = 374.4	5mg	QQ客服：215959384
5,7,3',4'-四甲氧基黄酮; 5,7,3',4'-Tetramethoxyflavone	CFN91116	855-97-0	C₁₉H₁₈O₆ = 342.3	20mg	QQ客服：1413575084
栎精-3,7,3’,4’-四甲醚; Retusin	CFN89520	1245-15-4	C₁₉H₁₈O₇ = 358.34	10mg	QQ客服：1457312923
槲皮素3,5,7,3',4'-五甲基醚; Quercetin 3,5,7,3,4-pentamethyl ether	CFN70262	1247-97-8	C₂₀H₂₀O₇ = 372.4	5mg	QQ客服：215959384

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.1616 mL	15.8078 mL	31.6156 mL	63.2311 mL	79.0389 mL
5 mM	0.6323 mL	3.1616 mL	6.3231 mL	12.6462 mL	15.8078 mL
10 mM	0.3162 mL	1.5808 mL	3.1616 mL	6.3231 mL	7.9039 mL
50 mM	0.0632 mL	0.3162 mL	0.6323 mL	1.2646 mL	1.5808 mL
100 mM	0.0316 mL	0.1581 mL	0.3162 mL	0.6323 mL	0.7904 mL