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  • 棕鳞矢车菊黄酮素

    Jaceidin

    棕鳞矢车菊黄酮素
    产品编号 CFN99032
    CAS编号 10173-01-0
    分子式 = 分子量 C18H16O8 = 360.3
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Flavonoids
    植物来源 The barks of Centaurea bracteata Scop.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    棕鳞矢车菊黄酮素 CFN99032 10173-01-0 1mg QQ客服:1457312923
    棕鳞矢车菊黄酮素 CFN99032 10173-01-0 5mg QQ客服:1457312923
    棕鳞矢车菊黄酮素 CFN99032 10173-01-0 10mg QQ客服:1457312923
    棕鳞矢车菊黄酮素 CFN99032 10173-01-0 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Zurich (Switzerland)
  • Subang Jaya Medical Centre (Malaysia)
  • Siksha O Anusandhan University (India)
  • Universidade Federal de Pernambuco (UFPE) (Brazil)
  • Medizinische Universit?t Wien (Austria)
  • Kyung Hee University (Korea)
  • University of Fribourg (Switzerland)
  • Utah State University (USA)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • The University of Newcastle (Australia)
  • Stanford University (USA)
  • Charles Sturt University (Denmark)
  • Universidad de Ciencias y Artes de Chiapas (Mexico)
  • The Institute of Cancer Research (United Kingdom)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Phytother Res.2020, 34(4):788-795.
  • Heliyon.2023, 9:e21652.
  • Comput Biol Chem.2019, 83:107096
  • Journal of Applied Pharmaceutical Science2022, 0(00), pp:001-007
  • J Pharmaceut Biomed2020, 182:113110
  • J of Applied Biological Chem.2020, 63(2):147-152
  • Foods.2023, 12(12):2412.
  • Journal of Third Military Medical University2019, 41(2):110-115
  • Life Sci.2021, 270:119074.
  • Molecules.2020, 25(3):734
  • The Journal of Internal Korean Medicine2015, 36(4):486-497
  • Foods.2021, 10(12):2929.
  • Bulletin of Health Research2016, 44(4):279-286
  • Heliyon.2022, e12337.
  • Food Chem.2021, 377:131976.
  • Anticancer Res.2022, 42(9):4403-4410.
  • Phytomedicine.2017, 24:77-86
  • J Ethnopharmacol.2020, 269:113752.
  • J Ethnopharmacol.2024, 318:116863.
  • J Pharm Biomed Anal.2016, 129:50-59
  • Natural Product Communications2020, doi: 10.1177.
  • Molecules.2018, 23(12):E3103
  • Int J Mol Sci.2022, 23(15):8687.
  • ...
  • 生物活性
    Description: Jaceidin demonstrates modest antioxidant activity, in a dose-dependent manner.
    In vitro:
    Fitoterapia. 2004 Dec;75(7-8):629-33.
    Antiplatelet activity of Varthemia iphionoides.[Pubmed: 15567236]

    METHODS AND RESULTS:
    Aqueous and alcoholic extracts, volatile oil and four flavonoids, xanthomicrol (1), kumatokenin (2), jaceidin (3) and 3, 3'-di-O-methylquercetin (4), isolated from Varthemia iphionoides were investigated for their in vitro anti-platelet activity. Aqueous extract and compounds (1), (2) and (4) showed anti-platelet activity. Volatile oil and the alcoholic extract did not exhibit any anti-platelet activity.
    CONCLUSIONS:
    Structures of the isolated compounds (1)-(4) were determined by spectroscopic methods (UV, IR, MS, (1)H-NMR).
    Nat Prod Commun. 2010 May;5(5):729-32.
    Protective effect on human lymphocytes of some flavonoids isolated from two Achillea species.[Pubmed: 20521537]
    This study was conducted to elucidate the in vitro protective effect of five flavonoids [apigenin (1), apigenin-7-O-glucoside (2), centaureidin (3), jaceidin (4) and quercetin (5)] against chromosomal damage in mitogen-induced human lymphocytes.
    METHODS AND RESULTS:
    Using the Cytochalasin-B blocked micronucleus (CBMN) assay, in which the biomarker of chromosome breakage and/or chromosome loss is the elevated frequency of micronucleus (MN) in binucleated (BN) cells, the presence of flavonoid 2 in minimal concentration (3 microg/mL) gave a 35.5% decrease in the frequency of MN when compared with control human lymphocytes. The same concentration of flavonoids 1, 3 and 4, reduced the MN frequency by 24.4%, 28.0% and 28.0%, respectively. Higher concentrations (6 microg/mL and 10 microg/mL) seemed less effective. Flavonoid 5 (3 microg/mL) induced a slight decrease in MN frequency (5%), while higher doses (6 microg/mL and 10 microg/mL) provoked an increase of DNA damage. The comparable values for the cytokinesis-block proliferation index (CBPI) of the tested flavonoids and positive control suggested an inhibitory effect on lymphocyte proliferation.
    CONCLUSIONS:
    In the DPPH scavenging assay, flavonoids 1-4 demonstrated modest activity, in a dose-dependent manner, compared with the synthetic antioxidants BHT and Trolox, while 5 exhibited comparably high antioxidative activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.7755 mL 13.8773 mL 27.7546 mL 55.5093 mL 69.3866 mL
    5 mM 0.5551 mL 2.7755 mL 5.5509 mL 11.1019 mL 13.8773 mL
    10 mM 0.2775 mL 1.3877 mL 2.7755 mL 5.5509 mL 6.9387 mL
    50 mM 0.0555 mL 0.2775 mL 0.5551 mL 1.1102 mL 1.3877 mL
    100 mM 0.0278 mL 0.1388 mL 0.2775 mL 0.5551 mL 0.6939 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    附子亭碱; Fuzitine CFN95337 142287-96-5 C20H24NO4 = 342.4 5mg QQ客服:2159513211
    磷酸二甲氨乙酯; Demanyl phosphate CFN00071 6909-62-2 C4H12NO4P = 169.12 5mg QQ客服:3257982914
    布雷非德菌素A; Brefeldin A CFN60308 20350-15-6 C16H24O4 = 280.36 5mg QQ客服:215959384
    Hedyotisol B; Hedyotisol B CFN97877 95839-45-5 C42H50O16 = 810.9 5mg QQ客服:2056216494

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