α-鼠李糖

alpha-L-Rhamnose

	产品编号	CFN90450
	CAS编号	3615-41-6
	分子式 = 分子量	C₆H₁₂O₅ = 164.16
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Miscellaneous
	植物来源	The leaves of Rhus toxicodendron
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

提供自定义包装

产品名称	产品编号	CAS编号	包装	QQ客服
α-鼠李糖	CFN90450	3615-41-6	10mg	QQ客服：2056216494
α-鼠李糖	CFN90450	3615-41-6	20mg	QQ客服：2056216494
α-鼠李糖	CFN90450	3615-41-6	50mg	QQ客服：2056216494
α-鼠李糖	CFN90450	3615-41-6	100mg	QQ客服：2056216494

存储与注意事项

1. 在您收到产品后请检查产品。如无问题，请将产品存入冰霜并且样品瓶保持密封，产品可以存放长达24个月（2-8摄氏度）。

2. 只要有可能，产品溶解后，您应该在同一天应用于您的实验。但是，如果您需要提前做预实验，或者需要全部溶解，我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。通常，这些可用于长达两周。使用前，打开样品瓶前，我们建议您将产品平衡至室温至少1小时。

3. 需要更多关于溶解度，使用和处理的建议？请发送电子邮件至：service@chemfaces.com

订购流程

1. 在线订购

请联系我们QQ客服

2. 电话订购

请拨打电话：
027-84237683 或 027-84237783

3. 邮件或传真订购

发送电子邮件到: manager@chemfaces.com 或
发送传真到：027-84254680

提供订购信息

为了方便客户的订购，请需要订购ChemFaces产品的客户，在下单的时候请提供下列信息，以供我们快速为您建立发货信息。

1. 产品编号（CAS No.或产品名称）

2. 发货地址

3. 联系方法 (联系人，电话）

4. 开票抬头 (如果需要发票的客户）

5. 发票地址（发货地址与发票地址不同）

发货时间

1. 付款方式为100%预付款客户，我们将在确认收到货款后当天或1-3个工作日发货。

2. 付款方式为月结的客户，我们承诺在收到订单后当天或1-3个工作日内发货。

3. 如果客户所需要的产品，需要重新生产，我们有权告知客户，交货时间需要延期。

ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

John Innes Centre (United Kingdom)

University of Beira Interior (Portugal)

Universidad de Antioquia (Colombia)

Universidade Federal de Pernambuco (UFPE) (Brazil)

University of Minnesota (USA)

Periyar University (India)

Mendel University in Brno (Czech Republic)

University of Perugia (Italy)

University of Queensland (Australia)

VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)

University of Toulouse (France)

National Chung Hsing University (Taiwan)

Seoul National University (Korea)

Charles University in Prague (Czech Republic)

More...

Description:

Addition of the Rhamnose-rich polysaccharide, RROP-1, to normal human dermal fibroblasts (NHDFs) and human endothelial cells produced a dose-dependent stimulation of the calcium-signaling pathway, inducing fast and transient increases in Ca2 influx and intracellular free Ca2 level.

Targets:

Calcium Channel

In vitro:

Biochim Biophys Acta. 2008 Dec;1780(12):1388-94.

The alpha-L-Rhamnose recognizing lectin site of human dermal fibroblasts functions as a signal transducer: modulation of Ca2+ fluxes and gene expression.[Pubmed: 18708125]

An alpha-L-Rhamnose specific lectin site was described on human skin keratinocytes and fibrobasts. The addition of Rhamnose-rich oligo- and polysaccharides (RROPs) to fibroblasts has been shown to stimulate cell proliferation and increase extracellular matrix biosynthesis, suggesting that this lectin site functions as a "true" receptor transmitting messages to the cell interior.
METHODS AND RESULTS:
It was confirmed here that addition of the Rhamnose-rich polysaccharide, RROP-1, to normal human dermal fibroblasts (NHDFs) and human endothelial cells produced a dose-dependent stimulation of the calcium-signaling pathway, inducing fast and transient increases in Ca2 influx and intracellular free Ca2 level. The Rhamnose-rich oligosaccharide RROP-3 as well as l-Rhamnose alone were also able to trigger similar intracellular free Ca2 concentration increases in NHDFs. Moreover, the recording of the RROP-1-induced modification of the gene-expression profile in fibroblasts showed that this polysaccharide triggered a down-regulation of the expression of several growth factors, adhesion molecules and extracellular matrix proteins involved in pro-tumoral activity and/or fibrotic processes.
CONCLUSIONS:
These results further support the hypothesis of a receptor function for the Rhamnose-recognizing lectin site in fibroblasts. Anti-fibrotic and anti-tumoral potential of RROP-1 remains to be further explored.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
1,5-酐-D-山梨糖醇; 1,5-Anhydro-D-glucitol	CFN90078	154-58-5	C₆H₁₂O₅ = 164.16	5mg	QQ客服：1413575084
果糖; Fructose	CFN98121	57-48-7	C₆H₁₂O₆ = 180.16	20mg	QQ客服：3257982914
1,2-O-异亚丙基-beta-D-吡喃果糖; 1,2-O-Isopropylidene-beta-D-fructopyranose	CFN97141	66900-93-4	C₉H₁₆O₆ = 220.2	5mg	QQ客服：1413575084
1,2:4,5-Di-O-isopropylidene-beta-D-fructopyranose; 1,2:4,5-Di-O-isopropylidene-beta-D-fructopyranose	CFN98273	25018-67-1	C₁₂H₂₀O₆ = 260.3	5mg	QQ客服：1413575084
α-鼠李糖; alpha-L-Rhamnose	CFN90450	3615-41-6	C₆H₁₂O₅ = 164.16	20mg	QQ客服：2159513211
鼠李糖; L-Rhamnose	CFN99545	6155-35-7	C₆H₁₄O₆ = 182.17	20mg	QQ客服：1413575084
D-(+)岩藻糖; D-(+)-Fucose	CFN90954	3615-37-0	C₆H₁₂O₅ = 164.16	20mg	QQ客服：2056216494
D(+)-无水葡萄糖; D-(+)-Glucose	CFN99769	50-99-7	C₆H₁₂O₆ = 180.16	20mg	QQ客服：1413575084
葡萄糖醛酸; Glucuronic acid	CFN91487	6556-12-3	C₆H₁₀O₇ = 194.1	20mg	QQ客服：215959384
半乳糖; D-Galactose	CFN91731	59-23-4	C₆H₁₂O₆ = 180.16	20mg	QQ客服：215959384

信息支持

公司简介
订购流程
付款方式
退换货政策

ChemFaces提供的产品仅用于科学研究使用，不用于诊断或治疗程序。

联系方式

电机：027-84237783
传真：027-84254680
在线QQ: 1413575084
E-Mail：manager@chemfaces.com

湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房

ChemFaces为科学家，科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产。

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	6.0916 mL	30.4581 mL	60.9162 mL	121.8324 mL	152.2904 mL
5 mM	1.2183 mL	6.0916 mL	12.1832 mL	24.3665 mL	30.4581 mL
10 mM	0.6092 mL	3.0458 mL	6.0916 mL	12.1832 mL	15.229 mL
50 mM	0.1218 mL	0.6092 mL	1.2183 mL	2.4366 mL	3.0458 mL
100 mM	0.0609 mL	0.3046 mL	0.6092 mL	1.2183 mL	1.5229 mL