蛇根亭碱
Serpentinine
|
|
产品编号 |
CFN98499 |
| CAS编号 |
36519-42-3 |
| 分子式 = 分子量 |
C42H44N4O5 = 684.8 |
| 产品纯度 |
>=98% |
| 物理属性 |
Powder |
| 化合物类型 |
Alkaloids |
| 植物来源 |
The roots of Rauvolfia verticillata (Lour.) Baill. |
| ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 |
|
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| 蛇根亭碱 |
CFN98499 |
36519-42-3 |
1mg |
QQ客服：2056216494 |
| 蛇根亭碱 |
CFN98499 |
36519-42-3 |
5mg |
QQ客服：2056216494 |
| 蛇根亭碱 |
CFN98499 |
36519-42-3 |
10mg |
QQ客服：2056216494 |
| 蛇根亭碱 |
CFN98499 |
36519-42-3 |
20mg |
QQ客服：2056216494 |
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Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
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国外学术期刊发表的引用ChemFaces产品的部分文献
| Description: |
Serpentinine may have antihypertensive effect. |
| In vitro: |
| Current Hypertension Reviews,2010, 6(3):190-8. | | Resurgence of Herbal Antihypertensives in Management of Hypertension.[Reference: WebLink] |
Hypertension is one of the major cardiovascular problems and causes a number of vascular disorders. Until the 1940s majority of the diseases were treated by traditional drugs obtained from plants/herbs only. Even the first potent herbal antihypertensive was obtained from root of Rauwolfia serpentina, a famous Ayurvedic plant but soon the modern antihypertensives took the center-stage because of their precise, defined and fast action. However, due to their growing adverse effects, interest in the use of these drugs also gradually started waning. This has lead to the resurgence of marked awareness about traditional medicines and a considerable renewed global interest in the plant based drugs. Much emphasis is now being given to validate the extract/fraction as well as single molecules obtained from plant resources based on their traditional claims.
METHODS AND RESULTS:
In this review, we have laid emphasis on the mechanistic aspect of antihypertensive effect of some medicinal plants and their therapeutic use. We have further tried to shed light on the attempts being made for the validation and documentation of traditional plants and herbs for their future development as potential therapy in hypertension. What's already known? • The herbal medications had been used since long to treat various cardiovascular disorders including high blood pressure before the arrival of modern therapy. • Global interest has now been renewed in herbal medicines but need authentication and validation in support of their therapeutic value. What this article may add? • This review emphasizes the mechanistic aspect of herbal medicines, their therapeutic values in clinical situation as well as present measures and recent approaches to validate and document their antihypertensive efficacies. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.4603 mL |
7.3014 mL |
14.6028 mL |
29.2056 mL |
36.507 mL |
| 5 mM |
0.2921 mL |
1.4603 mL |
2.9206 mL |
5.8411 mL |
7.3014 mL |
| 10 mM |
0.146 mL |
0.7301 mL |
1.4603 mL |
2.9206 mL |
3.6507 mL |
| 50 mM |
0.0292 mL |
0.146 mL |
0.2921 mL |
0.5841 mL |
0.7301 mL |
| 100 mM |
0.0146 mL |
0.073 mL |
0.146 mL |
0.2921 mL |
0.3651 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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