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  • 松脂醇二葡萄糖苷

    Pinoresinol diglucoside

    松脂醇二葡萄糖苷
    产品编号 CFN99994
    CAS编号 63902-38-5
    分子式 = 分子量 C32H42O16 = 682.67
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Lignans
    植物来源 The barks of Eucommia ulmoides.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    松脂醇二葡萄糖苷 CFN99994 63902-38-5 10mg QQ客服:2159513211
    松脂醇二葡萄糖苷 CFN99994 63902-38-5 20mg QQ客服:2159513211
    松脂醇二葡萄糖苷 CFN99994 63902-38-5 50mg QQ客服:2159513211
    松脂醇二葡萄糖苷 CFN99994 63902-38-5 100mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • University of Toulouse (France)
  • University of Vigo (Spain)
  • FORTH-IMBB (Greece)
  • University of Padjajaran (Indonesia)
  • University of Auckland (New Zealand)
  • University of Amsterdam (Netherlands)
  • Hamdard University (India)
  • Sant Gadge Baba Amravati University (India)
  • Helmholtz Zentrum München (Germany)
  • Guangzhou Institutes of Biomedicine and Health (China)
  • Tohoku University (Japan)
  • Srinakharinwirot University (Thailand)
  • Michigan State University (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Int J Mol Sci.2021, 22(11):5503.
  • Horticulture Research2023, uhad164.
  • Biomolecules.2019, 9(11):E696
  • Pharmacol Rep.2017, 69(6):1224-1231
  • Rev. Chim.2020, 71(3),558-564
  • Environ Toxicol.2020, doi: 10.1002
  • Molecules2020, 25(4):892
  • Bioorg Med Chem.2020, 28(12):115553.
  • Appl. Sci.2022, 12(4), 2032.
  • Hum Exp Toxicol.2017, 36(11):1169-1176
  • Front Immunol.2017, 8:1542
  • Life (Basel).2022, 12(12):2107.
  • Curr Issues Mol Biol.2023, ;45(2):1601-1612.
  • Foods.2021, 10(11):2754.
  • Buildings2023, 13(5), 1112.
  • Phytother Res.2022, 10.1002:ptr.7602.
  • Biochemical Systematics and Ecology2018, 81
  • Int J Mol Sci.2021, 22(9):5012.
  • Neurotox Res.2022, 40(6):1937-1947.
  • Phytomedicine.2022, 100:154036.
  • BioRxiv-The Preprint server for biology2023, 586957.
  • BMC Complement Med Ther.2023, 23(1):264.
  • Mol Pharm.2018, 15(8):3285-3296
  • ...
  • 生物活性
    Description: Pinoresinol diglucoside is a putative α-glucosidase inhibiting compound, has antihypertensive activity. It is a heat shock factor 1 inducer, increased expression of HSF1 by a factor of 1.041 at 3 μM.
    Targets: HSF-1 | α-glucosidase
    In vitro:
    Chem Biodivers. 2013 Jul;10(7):1322-7.
    Heat shock factor 1 inducers from the bark of Eucommia ulmoides as cytoprotective agents.[Pubmed: 23847077]
    The barks of Eucommia ulmoides (Eucommiae Cortex, Eucommiaceae) have been used as a traditional medicine in Korea, Japan, and China to treat hypertension, reinforce the muscles and bones, and recover the damaged liver and kidney functions.
    METHODS AND RESULTS:
    Among these traditional uses, to establish the recovery effects on the damaged organs on the basis of phytochemistry, the barks of E. ulmoides have been investigated to afford three known phenolic compounds, coniferaldehyde glucoside (1), bartsioside (2), and feretoside (3), which were found in the family Eucommiaceae for the first time. The compounds 1-3 were evaluated for their inducible activities on the heat shock factor 1 (HSF1), and heat shock proteins (HSPs) 27 and 70, along with four compounds, geniposide (4), geniposidic acid (5), pinoresinol diglucoside (6), and liriodendrin (7), which were previously reported from E. ulmoides. Compounds 1-7 increased expression of HSF1 by a factor of 1.214, 1.144, 1.153, 1.114, 1.159, 1.041, and 1.167 at 3 μM, respectively.
    CONCLUSIONS:
    Coniferaldehyde glucoside (1) showed the most effective increase of HSF1 and induced successive expressions of HSP27 and HSP70 in a dose-dependent manner without cellular cytotoxicity, suggesting a possible application as a HSP inducer to act as cytoprotective agent.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.4648 mL 7.3242 mL 14.6484 mL 29.2967 mL 36.6209 mL
    5 mM 0.293 mL 1.4648 mL 2.9297 mL 5.8593 mL 7.3242 mL
    10 mM 0.1465 mL 0.7324 mL 1.4648 mL 2.9297 mL 3.6621 mL
    50 mM 0.0293 mL 0.1465 mL 0.293 mL 0.5859 mL 0.7324 mL
    100 mM 0.0146 mL 0.0732 mL 0.1465 mL 0.293 mL 0.3662 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    (+)-表松脂素-4′-O-β-D-葡萄糖苷; Epipinoresinol-4-O-beta-D-glucoside CFN80044 24404-49-7 C26H32O11 = 520.52 5mg QQ客服:2159513211
    松脂醇二葡萄糖苷; Pinoresinol diglucoside CFN99994 63902-38-5 C32H42O16 = 682.67 20mg QQ客服:1457312923
    8-羟基松脂醇-4'-O-beta-D-吡喃葡萄糖苷; 8-Hydroxypinoresinol-4'-O-beta-D-glucopyranoside CFN95356 102582-69-4 C26H32O12 = 536.5 5mg QQ客服:3257982914
    8-羟基松脂醇二葡萄糖苷; 8-Hydroxypinoresinol diglucoside CFN95083 112747-99-6 C32H42O17 = 698.7 5mg QQ客服:215959384
    8-羟基松脂醇; 8-Hydroxypinoresinol CFN92432 81426-17-7 C20H22O7 = 374.4 5mg QQ客服:3257982914
    8-乙酰氧基松脂醇; 8-Acetoxypinoresinol CFN00449 81426-14-4 C22H24O8 = 416.43 5mg QQ客服:215959384
    波棱酮; Herpetone CFN90676 951677-22-8 C29H30O9 = 522.54 5mg QQ客服:2056216494
    O,O-二甲基鹅掌楸树脂醇 B; Yangambin CFN96416 13060-14-5 C24H30O8 = 446.49 10mg QQ客服:1457312923
    O,O-二甲基鹅掌楸树脂醇 A; Epiyangambin CFN96723 24192-64-1 C24H30O8 = 446.49 5mg QQ客服:1457312923
    松脂酚; 松脂醇; 松脂素; Pinoresinol CFN98775 487-36-5 C20H22O6 = 358.4 20mg QQ客服:3257982914

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