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  • 万寿菊苷


    产品编号 CFN95153
    CAS编号 19833-25-1
    分子式 = 分子量 C22H22O13 = 494.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Tagetes erecta
    产品名称 产品编号 CAS编号 包装 QQ客服
    万寿菊苷 CFN95153 19833-25-1 1mg QQ客服:2056216494
    万寿菊苷 CFN95153 19833-25-1 5mg QQ客服:2056216494
    万寿菊苷 CFN95153 19833-25-1 10mg QQ客服:2056216494
    万寿菊苷 CFN95153 19833-25-1 20mg QQ客服:2056216494
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.

    PMID: 30417089
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  • ...
  • 生物活性
    Description: Patulitrin has antioxidant, anti-inflammatory, and larvicidal activities, oral and topical administration of patuletin and patulitrin inhibited acute inflammation in mice.
    Targets: Antifection
    In vitro:
    Evid Based Complement Alternat Med. 2017;2017:9602368.
    Larvicidal Activity against Aedes aegypti and Chemical Characterization of the Inflorescences of Tagetes patula.[Pubmed: 29362590 ]

    The crude acetone extract (CAE) of defatted inflorescences of Tagetes patula was partitioned into five semipurified fractions: n-hexane (HF), dichloromethane (DF), ethyl acetate (EAF), n-butanol (BF), and aqueous (AQF). BF was fractionated by reversed-phase polyamide column chromatography, obtaining 34 subfractions, which were subjected to HSCCC, where patuletin and patulitrin were isolated. CAE and the fractions BF, EAF, DF, and AQF were analyzed by LC-DAD-MS, and patuletin and patulitrin were determined as the major substances in EAF and BF, respectively. BF was also analyzed by HPLC and capillary electrophoresis (CE), and patulitrin was again determined to be the main substance in this fraction. CAE and the semipurified fractions (750, 500, 300, 100, and 50 mg/L) were assayed for larvicidal activity against Aedes aegypti, with mortality rate expressed as percentage. All fractions except AQF showed insecticidal activity after 24 h exposure of larvae to the highest concentration. However, EAF showed the highest activity with more than 50% reduction in larval population at 50 mg/L.
    The insecticidal activity observed with EAF might have been due to the higher concentration of patuletin present in this fraction.
    Nat Prod Res. 2012;26(17):1584-93.
    Determination of antioxidant activity of extracts and fractions obtained from Galinsoga parviflora and Galinsoga quadriradiata, and a qualitative study of the most active fractions using TLC and HPLC methods.[Pubmed: 22085305 ]
    Taking into account the role of reactive oxygen species in the development of inflammation, and the application of the plants of genus Galinsoga Ruiz & Pav. in folk medicines for inflammatory states, we investigated and compared the antioxidant activities of particular Galinsoga extracts and fractions.
    The compositions of the most active fractions were studied using thin layer chromatography (TLC) and high-performance liquid chromatography (HPLC) methods. The extracts and fractions from Galinsoga parviflora Cav. and Galinsoga quadriradiata Ruiz et Pav. possess dose-dependent free radical-scavenging ability against DPPH• and superoxide radicals, as well as inhibitory effects on linoleic acid peroxidation in a manner comparable to gallic acid. In the most active fractions, flavonoids, patulitrin, quercimeritrin, quercitagetrin and caffeoyl derivatives were detected.
    Our research demonstrates that the investigated herbs are an interesting source of preparations with significant antioxidant effects. Our results justify the use of both raw materials in inflammatory diseases, among others, due to their ability to prevent free radical-induced deleterious effects.
    In vivo:
    Int J Inflam. 2013;2013:309493.
    Effects of Flavonoids from French Marigold (Florets of Tagetes patula L.) on Acute Inflammation Model.[Pubmed: 24175111 ]

    The major components patuletin and patulitrin were isolated from French marigold (florets of Tagetes patula). Patuletin and patulitrin were found to inhibit acute inflammation in mice. Oral administration of patuletin and patulitrin significantly suppressed hind-paw edema induced by carrageenin and histamine, while topical application of patuletin and patulitrin significantly inhibited ear edema induced by 12-O-tetradecanoylphorbol-13-acetate and arachidonic acid.
    Thus, oral and topical administration of patuletin and patulitrin inhibited acute inflammation in mice. These results suggest the anti-inflammatory efficacy of French marigold.
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0227 mL 10.1133 mL 20.2265 mL 40.4531 mL 50.5663 mL
    5 mM 0.4045 mL 2.0227 mL 4.0453 mL 8.0906 mL 10.1133 mL
    10 mM 0.2023 mL 1.0113 mL 2.0227 mL 4.0453 mL 5.0566 mL
    50 mM 0.0405 mL 0.2023 mL 0.4045 mL 0.8091 mL 1.0113 mL
    100 mM 0.0202 mL 0.1011 mL 0.2023 mL 0.4045 mL 0.5057 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Lethedoside A; Lethedoside A CFN98100 221289-20-9 C24H26O11 = 490.5 5mg QQ客服:3257982914
    Lethedioside A; Lethedioside A CFN98201 221289-31-2 C29H34O15 = 622.6 5mg QQ客服:2056216494
    5-羟基-7,8,2',5'-四甲氧基黄酮 5-O-葡萄糖苷; 5-Hydroxy-7,8,2',5'-tetramethoxyflavone 5-O-glucoside CFN97595 942626-75-7 C25H28O12 = 520.49 5mg QQ客服:3257982914
    木犀草苷; 木犀草素-7-O-葡萄糖苷; Luteolin-7-O-glucoside CFN98565 5373-11-5 C21H20O11 = 448.38 20mg QQ客服:2056216494
    木犀草素-7-O-葡萄糖醛酸苷; Luteolin-7-O-glucuronide CFN98512 29741-10-4 C21H18O12 = 462.36 20mg QQ客服:3257982914
    忍冬苷; Lonicerin CFN95055 25694-72-8 C27H30O15 = 594.5 10mg QQ客服:1457312923
    木犀草素 7-芸香糖苷; Luteolin 7-rutinoside CFN93556 20633-84-5 C27H30O15 = 594.52 20mg QQ客服:3257982914
    木犀草素 5-葡萄糖苷; Luteollin 5-glucoside CFN98568 20344-46-1 C21H20O11 = 448.38 5mg QQ客服:1413575084
    芫花叶苷; Yuanhuanin CFN95127 83133-14-6 C22H22O11 = 462.4 5mg QQ客服:2056216494
    芫花素-5-O-茜黄苷; Yuankanin CFN95128 77099-20-8 C27H30O14 = 578.5 5mg QQ客服:1457312923





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