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  • 1,8-十七碳二烯-4,6-二炔-3,10-二醇

    Panaxydiol

    1,8-十七碳二烯-4,6-二炔-3,10-二醇
    产品编号 CFN92798
    CAS编号 708257-91-4
    分子式 = 分子量 C17H24O2 = 260.4
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Miscellaneous
    植物来源 The roots of Panax ginseng C. A. Mey.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    1,8-十七碳二烯-4,6-二炔-3,10-二醇 CFN92798 708257-91-4 1mg QQ客服:2056216494
    1,8-十七碳二烯-4,6-二炔-3,10-二醇 CFN92798 708257-91-4 5mg QQ客服:2056216494
    1,8-十七碳二烯-4,6-二炔-3,10-二醇 CFN92798 708257-91-4 10mg QQ客服:2056216494
    1,8-十七碳二烯-4,6-二炔-3,10-二醇 CFN92798 708257-91-4 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Cancer Research Initatives Foundation(CARIF) (Malaysia)
  • Centralised Purchases Unit (CPU), B.I.T.S (India)
  • University of Fribourg (Switzerland)
  • Leibniz Institute of Plant Biochemistry (Germany)
  • Pennsylvania State University (USA)
  • Gyeongsang National University (Korea)
  • Sri Ramachandra University (India)
  • Universite Libre de Bruxelles (Belgium)
  • Tokyo Woman's Christian University (Japan)
  • Sapienza University of Rome (Italy)
  • University of the Basque Country (Spain)
  • University of Eastern Finland (Finland)
  • University of Beira Interior (Portugal)
  • Sanford Burnham Medical Research Institute (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Life Sci.2021, 270:119074.
  • PLoS One.2018, 13(3):e0193386
  • Food Control2022, 132:108434.
  • Molecules.2022, 27(21):7514.
  • Ind Crops Prod.2014, 62:173-178
  • Evid Based Complement Alternat Med.2021, 2021:6687513.
  • JPC-Journal of Planar Chromatography 2017, 30(2)
  • Journal of Apiculture2019, 34(2):131-136
  • Journal of Functional Foods2022, 98:105271.
  • Appl. Sci.2020, 10(16),5482.
  • Food Chem.2019, 274:345-350
  • Front Pharmacol.2022, 13:883475.
  • Antiviral Res.2013, 98(3):386-93
  • Nat Prod Sci.2018, 24(3):206
  • Plants (Basel).2021, 10(6):1192.
  • Research Square2021, 10.21203.
  • Molecules.2019, 24(7):E1290
  • Journal of Physiology & Pathology in Korean Medicine.2018, 32(2): 106-112
  • J Traditional Thai Medical Res.2022, 8(1):pp1-14.
  • Exp Mol Med.2020, 52(4):629-642.
  • Int J Mol Sci.2022, 23(23):14545.
  • Molecules.2022, 27(19):6651.
  • Int J Mol Sci.2017, 18(5)
  • ...
  • 生物活性
    Description: Panaxydiol can inhibit rat liver cholesterol acyltransferase (ACAT) with IC50 values of 45 microM.
    In vitro:
    J Agric Food Chem. 2005 Apr 6;53(7):2518-23.
    Polyacetylenes from the Apiaceae vegetables carrot, celery, fennel, parsley, and parsnip and their cytotoxic activities.[Pubmed: 15796588]
    A dichloromethane extract of root celery yielded falcarinol, falcarindiol, panaxydiol, and the new polyacetylene 8-O-methylfalcarindiol.
    METHODS AND RESULTS:
    The structure of the new compound was established by one- and two-dimensional (1D and 2D) NMR, mass spectrometry, and optical rotation data. Nonpolar extracts of roots and bulbs of carrots, celery, fennel, parsley, and parsnip were investigated for their content of polyacetylenes by high-performance liquid chromatography with diode array detection (HPLC-DAD). All five species contained polyacetylenes, although carrots and fennel only in minor amounts. Additionally, the cytotoxicity of the four polyacetylenes against five different cell lines was evaluated by the annexin V-PI assay.
    CONCLUSIONS:
    Falcarinol proved to be the most active compound with a pronounced toxicity against acute lymphoblastic leukemia cell line CEM-C7H2, with an IC(50) of 3.5 micromol/L. The possible chemopreventive impact of the presented findings is discussed briefly.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.8402 mL 19.2012 mL 38.4025 mL 76.8049 mL 96.0061 mL
    5 mM 0.768 mL 3.8402 mL 7.6805 mL 15.361 mL 19.2012 mL
    10 mM 0.384 mL 1.9201 mL 3.8402 mL 7.6805 mL 9.6006 mL
    50 mM 0.0768 mL 0.384 mL 0.768 mL 1.5361 mL 1.9201 mL
    100 mM 0.0384 mL 0.192 mL 0.384 mL 0.768 mL 0.9601 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    镰叶芹二醇; Falcarindiol CFN98220 225110-25-8 C17H24O2 = 260.4 20mg QQ客服:215959384
    镰叶芹醇; Falcarinol CFN96027 21852-80-2 C17H24O = 244.4 10mg QQ客服:215959384
    人参炔K; Ginsenoyne K CFN96044 141947-42-4 C17H24O3 = 276.4 5mg QQ客服:2056216494
    党参炔醇; Lobetyol CFN92356 136171-87-4 C14H18O3 = 234.3 5mg QQ客服:1413575084
    党参炔苷; Lobetyolin CFN99104 136085-37-5 C20H28O8 = 396.43 20mg QQ客服:2159513211
    Lobetyolinin; Lobetyolinin CFN92357 142451-48-7 C26H38O13 = 558.6 10mg QQ客服:215959384
    (3E,5E,11E)-tridecatriene-7,9-diyne-1,2-diacetate; (3E,5E,11E)-tridecatriene-7,9-diyne-1,2-diacetate CFN95191 N/A C17H18O4 = 286.3 5mg QQ客服:2159513211
    11-羟基茉莉酸; 11-Hydroxyjasmonic acid CFN99457 140447-14-9 C12H18O4 = 226.3 5mg QQ客服:1413575084
    12-羟基茉莉酸; 12-Hydroxyjasmonic acid CFN99460 140631-27-2 C12H18O4 = 226.3 5mg QQ客服:2056216494
    (S,E)-癸-2,9-二烯-4,6-二炔-1,8-二醇; (S,E)-Deca-2,9-diene-4,6-diyne-1,8-diol CFN97501 931114-98-6 C10H10O2 = 162.2 5mg QQ客服:3257982914

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