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  • 硫酸尖刺碱

    Oxyacanthine sulfate

    硫酸尖刺碱
    产品编号 CFN70424
    CAS编号 6183-91-1
    分子式 = 分子量 C37H42N2O10S = 706.8
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 The roots of Berberis soulieana
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    硫酸尖刺碱 CFN70424 6183-91-1 1mg QQ客服:1457312923
    硫酸尖刺碱 CFN70424 6183-91-1 5mg QQ客服:1457312923
    硫酸尖刺碱 CFN70424 6183-91-1 10mg QQ客服:1457312923
    硫酸尖刺碱 CFN70424 6183-91-1 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of British Columbia (Canada)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • Tohoku University (Japan)
  • CSIRO - Agriculture Flagship (Australia)
  • Auburn University (USA)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Revista Brasileira de Farmacognosia2021, 31:794-804.
  • Molecules.2021, 26(13):4081.
  • Sci Rep.2021, 11(1):14180.
  • Drug Dev Res.2022, 83(7):1673-1682.
  • J of Archaeological Science:Reports2024, 53:104298
  • Microb Biotechnol.2021, 14(5):2009-2024.
  • Inflammation.2021, doi: 10.1007
  • J Pain Res.2022, 15:3469-3478.
  • J.the Korean Socie. Food Sci.&Nut.2023; 52(1):26-39.
  • Drug Chem Toxicol.2024, 1-10.
  • Anticancer Res.2021, 41(3):1357-1364.
  • Phytochemistry Letters2017, 449-455
  • J Nat Med.2017, 71(2):380-388
  • Neurochem Int.2018, 121:114-124
  • Biol Pharm Bull.2018, 41(11):1685-1693
  • Sci Rep. 2018, 1-9
  • Int J Mol Sci.2021, 22(19):10220.
  • Plants (Basel).2023, 12(5):1120.
  • J Med Food.2021, 24(3):209-217.
  • Br J Pharmacol.2020, 10.1111
  • Agronomy2023, 13(6), 1435.
  • J Sep Sci.2020, 201901140
  • Cell Signal.2022, 99:110433.
  • ...
  • 生物活性
    Description: Oxyacanthine can be used for the treatment of various inflammatory diseases such as lumbago, rheumatism and to reduce fever.
    In vivo:
    Life Sciences, 2002, 72(6):645-657.
    A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species.[Reference: WebLink]
    Roots and barks of various Berberis species are used as folk remedy for the treatment of various inflammatory diseases such as lumbago, rheumatism and to reduce fever.
    METHODS AND RESULTS:
    Six isoquinoline alkaloids namely berberine, berbamine, palmatine, oxyacanthine(Oxyacanthine sulfate), magnoflorine, and columbamine were isolated as the main components of alkaloidal fraction from the roots of Turkish Berberis species and effects were studied using various in vivo models in mice.
    CONCLUSIONS:
    All alkaloids inhibited inflammations in varying degrees, among them berberine, berbamine and palmatine were shown to possess significant and dose-dependent inhibitory activity against serotonin-induced hind paw oedema both on oral and topical applications and acetic acid-induced increase in vascular permeability on oral administration. Moreover, these three alkaloids were also shown to possess dose-dependent antinociceptive activity, which assessed by using the model based on the inhibition of p-benzoquinone-induced writhing movements as well as antipyretic activity on FCA-induced increased rectal temperature on subacute administration. However, all alkaloids induced gastric lesions in varying degrees.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.4148 mL 7.0741 mL 14.1483 mL 28.2965 mL 35.3707 mL
    5 mM 0.283 mL 1.4148 mL 2.8297 mL 5.6593 mL 7.0741 mL
    10 mM 0.1415 mL 0.7074 mL 1.4148 mL 2.8297 mL 3.5371 mL
    50 mM 0.0283 mL 0.1415 mL 0.283 mL 0.5659 mL 0.7074 mL
    100 mM 0.0141 mL 0.0707 mL 0.1415 mL 0.283 mL 0.3537 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    盐肤木内酯A; Rhuscholide A CFN97526 944804-58-4 C31H42O3 = 462.7 5mg QQ客服:1457312923
    鲁索利替尼; Ruxolitinib (INCB018424) CFN60063 941678-49-5 C17H18N6 = 306.37 5mg QQ客服:3257982914
    氧代表千金藤默星碱; Oxoepistephamiersine CFN98830 51804-68-3 C21H25NO7 = 403.4 5mg QQ客服:3257982914
    小白菊内酯; Parthenolide CFN98034 20554-84-1 C15H20O3 = 248.3 20mg QQ客服:3257982914

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