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  • Oleuropeic acid

    • Oleuropeic acid

    Oleuropeic acid

    Oleuropeic acid
    		产品编号 CFN98795
    CAS编号 5027-76-9
    分子式 = 分子量 C10H16O3 = 184.2
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Monoterpenoids
    植物来源 The leaves of Eucalyptus maideni
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Oleuropeic acid CFN98795 5027-76-9 1mg QQ客服：215959384
    Oleuropeic acid CFN98795 5027-76-9 5mg QQ客服：215959384
    Oleuropeic acid CFN98795 5027-76-9 10mg QQ客服：215959384
    Oleuropeic acid CFN98795 5027-76-9 20mg QQ客服：215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • Instituto de Investigaciones Agropecuarias (Chile)
  • Lund University (Sweden)
  • Shanghai University of TCM (China)
  • Calcutta University (India)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • Universitas islam negeri Jakarta (Indonesia)
  • Pennsylvania State University (USA)
  • Korea Food Research Institute(KFRI) (Korea)
  • Korea Institute of Oriental Medicine (Korea)
  • Universidade Federal de Santa Catarina (Brazil)
  • Stanford University (USA)
  • Worcester Polytechnic Institute (USA)
  • John Innes Centre (United Kingdom)
  • More...
    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Processes2021, 9(5),831.
  • VNU J of Science: Med.&Pharm. Sci.2023, 39(1):20-29.
  • ACS Omega.2022, 7(44):40009-40020.
  • Food Funct.2024, 15(8):4262-4275.
  • Korean J of Food Science&Technology 2017, 49(2):146-150
  • Evid-Based Compl Alt2020, 7202519:13
  • Drug Chem Toxicol.2020, 1-14.
  • J Food Biochem.2019, 43(9):e12970
  • British Jou. Med.&Med. Research2014, 1802-1811
  • Anticancer Agents Med Chem.2023, 23(10):1204-1210.
  • Revista Brasileira de Farmacognosia2021, 31:794-804.
  • J Biochem Mol Toxicol.2017, 31(9)
  • BMC Complement Altern Med.2017, 17(1):384
  • Sci Rep. 2017, 17332(7)
  • Advances in Traditional Medicine 2021, 21:779-789.
  • Mol Med Rep.2022, 26(4):299.
  • Sci Rep. 2024, 14(1):70.
  • Molecules.2017, 22(2)
  • Antioxidants (Basel).2020, 9(2):E99
  • BMC Plant Biol.2023, 23(1):239.
  • Oncotarget.2015, 6(31):30831-49
  • Toxins (Basel).2021, 13(9):593.
  • Earth Environ. Sci. 2021, 905:012080.
  • ...
    • 生物活性
    Description: (+)-Oleuropeic acid shows potent in vitro antitumor-promoting activity, it also suppresses an in vivo two-stage carcinogenesis induced with nitric oxide and 12-O-tetradecanoyl phorbol 13-acetate (TPA) on mouse skin.
    In vitro:
    J Agric Food Chem. 2014 Jan 8;62(1):144-51.
    Radical-scavenging compounds from olive tree (Olea europaea L.) wood.[Pubmed: 24328093]
    The purpose of this study was to complete knowledge on the chemical composition and radical-scavenging activity of olive tree wood.
    METHODS AND RESULTS:
    Two new monoterpene glycosides, (-)-Oleuropeic acid 6'-O-α-D-glucopyranosyl ester (6a) and (-)-perillic acid 1'-O-β-D-primeverosyl ester (8), together with the known compounds (-)-Oleuropeic acid (1), (-)-olivil (2), the aldehydic form of oleuropein aglycone (3), (+)-1-hydroxypinoresinol 1-O-β-D-glucopyranoside (4), (-)-Oleuropeic acid 1'-O-β-D-glucopyranosyl ester (5), (-)-Oleuropeic acid 6'-O-β-D-glucopyranosyl ester (6b), and (-)-olivil 4-O-β-D-glucopyranoside (7) were isolated from an ethyl acetate extract. The radical scavengers found (2-4 and 7) were detected and isolated with the help of the online HPLC-DAD-DPPH/ABTS technique.
    CONCLUSIONS:
    Compounds 2-4 and 7 displayed a higher antioxidative effect against the free radical DPPH than the reference BHT and lower than hydroxytyrosol, whereas compounds 1, 5, 6a, 6b, and 8 showed no activity.
    In vivo:
    J Nat Prod. 2000 Sep;63(9):1253-7.
    Cypellocarpins A-C, phenol glycosides esterified with oleuropeic acid, from Eucalyptus cypellocarpa.[Pubmed: 11000030]

    METHODS AND RESULTS:
    Three new phenol glycosides acylated with (+)-Oleuropeic acid, cypellocarpins A (1), B (2), and C (3), along with seven known compounds, were isolated from the dried leaves of Eucalyptus cypellocarpa. Structures of the new compounds were determined on the basis of spectroscopic methods, including 2D NMR experiments and chemical degradation. These new compounds and a known related glucoside (7) showed potent in vitro antitumor-promoting activity in a short-term bioassay evaluating the inhibitory effect on Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoyl phorbol 13-acetate (TPA).
    CONCLUSIONS:
    These compounds also suppressed an in vivo two-stage carcinogenesis induced with nitric oxide and TPA on mouse skin.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.4289 mL 27.1444 mL 54.2888 mL 108.5776 mL 135.722 mL
    5 mM 1.0858 mL 5.4289 mL 10.8578 mL 21.7155 mL 27.1444 mL
    10 mM 0.5429 mL 2.7144 mL 5.4289 mL 10.8578 mL 13.5722 mL
    50 mM 0.1086 mL 0.5429 mL 1.0858 mL 2.1716 mL 2.7144 mL
    100 mM 0.0543 mL 0.2714 mL 0.5429 mL 1.0858 mL 1.3572 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    L-紫苏醇; Perillyl alcohol CFN93581 536-59-4 C10H16O = 152.2 20mg QQ客服：3257982914
    橄榄苦苷酸 8-O-葡萄糖苷; Oleuropeic acid 8-O-glucoside CFN96125 865887-46-3 C16H26O8 = 346.4 5mg QQ客服：2056216494
    Cuniloside B; Cuniloside B CFN99285 1187303-40-7 C26H40O10 = 512.6 5mg QQ客服：3257982914
    2-羟基-1,8-桉树脑; 2-Hydroxy-1,8-cineole CFN97032 60761-00-4 C10H18O2 = 170.3 5mg QQ客服：3257982914
    alpha-松油醇; Terpineol CFN92688 98-55-5 C10H18O = 154.3 20mg QQ客服：3257982914
    α-松油醇; Alpha-Terpineol CFN80110 10482-56-1 C10H18O = 154.25 5mg QQ客服：2159513211
    4-萜烯醇; Terpinine-4-ol CFN94877 562-74-3 C10H18O = 154.3 50mg QQ客服：1457312923
    对薄荷烷-1,2,8-三醇; p-Menthane-1,2,8-triol CFN97064 62014-81-7 C10H20O3 = 188.3 5mg QQ客服：1457312923
    对萜品-1,3,8-三醇; p-Menthane-1,3,8-triol CFN99656 155348-06-4 C10H20O3 = 188.3 5mg QQ客服：1413575084
    Oleuropeic acid; Oleuropeic acid CFN98795 5027-76-9 C10H16O3 = 184.2 5mg QQ客服：215959384

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