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  • 新知母皂苷BII

    Officinalisinin I

    新知母皂苷BII
    产品编号 CFN90692
    CAS编号 57944-18-0
    分子式 = 分子量 C45H76O19 = 921.07
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Steroids
    植物来源 The rhizomes of Anemarrhena asphodeloides Bunge
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    新知母皂苷BII CFN90692 57944-18-0 10mg QQ客服:2159513211
    新知母皂苷BII CFN90692 57944-18-0 20mg QQ客服:2159513211
    新知母皂苷BII CFN90692 57944-18-0 50mg QQ客服:2159513211
    新知母皂苷BII CFN90692 57944-18-0 100mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Oslo (Norway)
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  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Food Composition and Analysis2022, 104417.
  • J of Pharmaceutical Analysis2020, doi: 10.1016
  • Legume Science2021, 3(4): e101.
  • Front Pharmacol.2021, 12:690113.
  • Korean Journal of Pharmacognosy.2020, 51(2):100-106
  • J of Food Quality2020, 8851285.
  • Korean J of Food Science&Technology 2017, 49(2):146-150
  • J Sci Food Agric.2022, 102(4):1628-1639
  • Molecules.2020, 25(17):3783.
  • J Ginseng Res.2022, 46(1):104-114.
  • Saudi Pharm J.2019, 27(1):145-153
  • Elife.2021, 10:e68058.
  • Int J Mol Sci.2021, 22(9):5012.
  • Exp Mol Med.2020, 52(4):629-642.
  • Iranian J. Pharm. Res.2021, 20(4):59-70
  • Natural Product Communications2021, 16(9):1-10.
  • J Ethnopharmacol.2021, 267:113615.
  • J Applied Biological Chemistry2021, 64(2):185-192
  • Primary and Industrial.2018, 52(11)
  • J Med Food.2022, 25(3):272-280.
  • Sci Rep. 2017, 17332(7)
  • Appl. Sci. 2021, 11(17),7829
  • Cosmetics2021, 8(3),91.
  • ...
  • 生物活性
    Description: Officinalisinin Ⅰcan effectively reduce the blood glucose and protect nerve injuryin diabetic mice.
    In vivo:
    China Journal of Traditional Chinese Medicine & Pharmacy, 2017 (2) :782-785.
    Study on hypoglycemic mechanism and central nerve protection of Officinalisinin Ⅰ in Rhizoma Anemarrhenae[Reference: WebLink]
    To study the hypoglycemic effect of Officinalisinin Ⅰin Rhizoma Anemarrhenae on diabetes, and discuss the hypoglycemic mechanism and protective effect on diabetic nephropathy.
    METHODS AND RESULTS:
    Glucose tolerance was measured in model mice induced by oral administration of alloxan.Inhibition of glycosidase activity was tested in vitro.GLP-1 was detected after fasting in diabetic mice.The levels of BDNF and GSH-PX in serum were detected by enzyme-linked immunosorbent assay(ELISA) after 20 days of medication.Officinalisinin I has the functions of lowering blood glucose and significantly improving the glucose tolerance of diabetic mice.In the experiment, the glycosidase inhibitor pathway was eliminated, andby promoting the generation of GLP-1 and BDNF and increasing the activity of GSH-PX Officinalisinin I achieves the hypoglycemic and neuroprotective effect.
    CONCLUSIONS:
    Officinalisinin I can effectively reduce the blood glucose and protect nerve injuryin diabetic mice.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.0857 mL 5.4285 mL 10.8569 mL 21.7139 mL 27.1423 mL
    5 mM 0.2171 mL 1.0857 mL 2.1714 mL 4.3428 mL 5.4285 mL
    10 mM 0.1086 mL 0.5428 mL 1.0857 mL 2.1714 mL 2.7142 mL
    50 mM 0.0217 mL 0.1086 mL 0.2171 mL 0.4343 mL 0.5428 mL
    100 mM 0.0109 mL 0.0543 mL 0.1086 mL 0.2171 mL 0.2714 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    知母皂苷C; Timorsaponin C CFN90779 185432-00-2 C45H74O18 = 903.1 5mg QQ客服:2159513211
    伪原皂苷Pa; Parisyunnanoside B CFN90704 945865-37-2 C50H80O21 = 1016.0 10mg QQ客服:2056216494
    伪原薯蓣皂苷; Pseudoprotodioscin CFN90694 102115-79-7 C51H82O2 = 1031.18 20mg QQ客服:215959384
    黄山药皂苷C; Dioscoreside C CFN95345 C52H84O22 = 1061.2 5mg QQ客服:1457312923
    黄山药皂苷E; Dioscoreside E CFN95346 435321-73-6 C52H84O23 = 1077.2 5mg QQ客服:3257982914
    蒺藜皂苷K; Terrestrosin K CFN90822 193605-07-1 C51H82O24 = 1079.2 10mg QQ客服:215959384
    伪原皂苷Pb; Pseudoproto Pb CFN90705 102100-46-9 C57H92O25 = 1177.4 5mg QQ客服:1413575084
    新知母皂苷BII; Officinalisinin I CFN90692 57944-18-0 C45H76O19 = 921.07 20mg QQ客服:215959384
    知母皂苷E; Anemarsaponin E CFN99533 136565-73-6 C46H78O19 = 934.03 10mg QQ客服:2056216494
    (3beta,22alpha)-26-(beta-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl 2-O-(6-deoxy-alpha-mannopyranosyl)-beta-glucopyranosiduronic acid; (3beta,22alpha)-26-(beta-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl 2-O-(6-deoxy-alpha-mannopyranosyl)-beta-glucopyranosiduronic acid CFN95321 107783-53-9 C46H74O19 = 931.1 20mg QQ客服:215959384

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