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  • 新比克白芷内酯

    Neobyakangelicol

    新比克白芷内酯
    产品编号 CFN98462
    CAS编号 35214-82-5
    分子式 = 分子量 C17H16O6 = 316.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Coumarins
    植物来源 The roots of Angelica dahurica
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    新比克白芷内酯 CFN98462 35214-82-5 1mg QQ客服:1413575084
    新比克白芷内酯 CFN98462 35214-82-5 5mg QQ客服:1413575084
    新比克白芷内酯 CFN98462 35214-82-5 10mg QQ客服:1413575084
    新比克白芷内酯 CFN98462 35214-82-5 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universidad de Buenos Aires (Argentina)
  • Mahatma Gandhi University (India)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • Universita' Degli Studi Di Cagliari (Italy)
  • University of Perugia (Italy)
  • Monash University Sunway Campus (Malaysia)
  • Complutense University of Madrid (Spain)
  • Universidad Veracuzana (Mexico)
  • Instituto de Investigaciones Agropecuarias (Chile)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • Universidade Católica Portuguesa (Portugal)
  • Sri Ramachandra University (India)
  • University of Fribourg (Switzerland)
  • University of Dicle (Turkey)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Korean Society of Food Science & Nutrition2021, 50(9): 962-970
  • Int. J. Mol. Sci.2022, 23(8), 4130.
  • Pharmaceutics.2021, 13(2):187.
  • Journal of Ginseng Research2019, 10.1016
  • JPC-Journal of Planar Chromatography2023, 36:179-190
  • Kasetsart University2022, ethesis.1144.
  • Appl. Sci. 2021, 11(1),14.
  • J Food Biochem.2019, 43(9):e12970
  • Cardiovasc Toxicol.2021, 21(11):947-963.
  • LWT - Food Science and Technology2022, 164:113627
  • Appl Biochem Biotechnol.2022, s12010-022-04166-2.
  • Oxid Med Cell Longev.2022, 2022:9139338.
  • Food Sci Nutr.2023, 11(9):5532-5542.
  • J Pharm Biomed Anal.2019, 164:119-127
  • Phytother Res.2019, 33(5):1490-1500
  • Front Pharmacol.2021, 12:765521.
  • J Enzyme Inhib Med Chem.2019, 34(1):134-143
  • Front Immunol.2020, 11:598556.
  • Sci Rep. 2018, 1-9
  • Int J Mol Sci.2020, 21(19),7070.
  • J Plant Biotechnol.2023, 50:070-075.
  • Food Chem.2017, 221:1135-1144
  • Planta Med.2016, 82(13):1208-16
  • ...
  • 生物活性
    Description: Neobyakangelicol has anti-lipolytic hormones effects, it can strongly inhibit insulin- stimulated lipogenesis.
    In vitro:
    J Ethnopharmacol. 2004 Aug;93(2-3):243-6.
    Antioxidative activity of furanocoumarins isolated from Angelicae dahuricae.[Pubmed: 15234759 ]

    METHODS AND RESULTS:
    The methylene chloride extract of the root of Angelicae dahuricae showed high protective activity against 2,2'-azobis (2-aminodinopropane) dihydrochloride (AAPH)-induced cellular damage. From this extract, 11 furanocoumarins were isolated, namely oxypeucedanin hydrate, 9-hydroxy-4-methoxypsoralen, byakangelicin, pabulenol, alloisoimperatorin, Neobyakangelicol, byakangelicol, oxypeucedanin, imperatorin, phellotorin and isoimperatorin, respectively.
    CONCLUSIONS:
    Among these 11 furanocoumarins, 9-hydroxy-4-methoxypsoralen and alloisoimperatorin displayed potent antioxidant effects against the DPPH radical and against renal epithelial cell injury by using AAPH to generate peroxyl radicals in vitro.
    Planta Med. 1982 Jul;45(3):183-7.
    Effects of various coumarins from roots of Angelica dahurica on actions of adrenaline, ACTH and insulin in fat cells.[Reference: WebLink]

    METHODS AND RESULTS:
    Experiments were carried out on the effects of various coumarins on the actions of adrenaline, adrenocorticotropic hormone (ACTH) and insulin in fat cells isolated from rats. Furocoumarins such as oxypeucedanin hydrate, bergapten, xanthotoxin, imperatorin, phellopterin activated adrenaline-induced lipolysis. Furocoumarins such as oxypeucedanin hydrate, imperatorin and phellopterin also activated ACTH-induced lipolysis. On the other hand, furocoumarins such as byak-angelicin, Neobyakangelicol and isopimpinellin strongly inhibited insulin-stimulated lipogenesis.
    CONCLUSIONS:
    Therefore, the crude drug “Byakushi” may activate the actions of lipolytic hormones and selectively inhibit the effects of anti-lipolytic hormones.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.1616 mL 15.8078 mL 31.6156 mL 63.2311 mL 79.0389 mL
    5 mM 0.6323 mL 3.1616 mL 6.3231 mL 12.6462 mL 15.8078 mL
    10 mM 0.3162 mL 1.5808 mL 3.1616 mL 6.3231 mL 7.9039 mL
    50 mM 0.0632 mL 0.3162 mL 0.6323 mL 1.2646 mL 1.5808 mL
    100 mM 0.0316 mL 0.1581 mL 0.3162 mL 0.6323 mL 0.7904 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    别异欧前胡素; Alloisoimperatorin CFN95012 35214-83-6 C16H14O4 = 270.3 5mg QQ客服:1413575084
    别欧前胡素; Alloimperatorin CFN93037 642-05-7 C16H14O4 = 270.28 10mg QQ客服:1413575084
    珊瑚菜素; Phellopterin CFN90495 2543-94-4 C17H16O5 = 300.3 20mg QQ客服:1457312923
    白当归脑; Byakangelicol CFN98167 26091-79-2 C17H16O6 = 316.31 20mg QQ客服:2159513211
    白当归素; Byakangelicin CFN98152 482-25-7 C17H18O7 = 334.32 20mg QQ客服:1413575084
    新比克白芷内酯; Neobyakangelicol CFN98462 35214-82-5 C17H16O6 = 316.3 5mg QQ客服:1457312923

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