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  • 异金雀花素

    Isoscoparin

    异金雀花素
    产品编号 CFN90965
    CAS编号 20013-23-4
    分子式 = 分子量 C22H22O11 = 462.40
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The seeds of Alliaria petiolata.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    异金雀花素 CFN90965 20013-23-4 1mg QQ客服:2056216494
    异金雀花素 CFN90965 20013-23-4 5mg QQ客服:2056216494
    异金雀花素 CFN90965 20013-23-4 10mg QQ客服:2056216494
    异金雀花素 CFN90965 20013-23-4 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universitas islam negeri Jakarta (Indonesia)
  • Research Unit Molecular Epigenetics (MEG) (Germany)
  • Semmelweis Unicersity (Hungary)
  • Korea Intitute of Science and Technology (KIST) (Korea)
  • Deutsches Krebsforschungszentrum (Germany)
  • University of Eastern Finland (Finland)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Gyeongsang National University (Korea)
  • FORTH-IMBB (Greece)
  • University of Toronto (Canada)
  • Massachusetts General Hospital (USA)
  • Kyung Hee University (Korea)
  • Warszawski Uniwersytet Medyczny (Poland)
  • Johannes Gutenberg University Mainz (JGU) (Germany)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Ind. J. Pharm. Edu. Res.2023; 57(3):1132-1139.
  • Chemistry of Vegetable Raw Materials2019, 3:119-127
  • Journal of Chromatography A2020, 460942
  • Int J Anal Chem.2017, 2017:1254721
  • Separations2021, 8(6),80.
  • Evid Based Complement Alternat Med.2017, 2017:6360836
  • J Appl Pharm Sci.2022, 12(04):044-053
  • Plants (Basel).2021, 10(4):702.
  • J Mol Med (Berl).2018, 96(7):661-672
  • J.the Korean Socie. Food Sci.&Nut.2023; 52(1):26-39.
  • Kor. J. Pharmacogn.2016, 47(1):62-72
  • Neurochem Int.2018, 121:114-124
  • Mol Med Rep.2014, 9(5):1653-9
  • BMC Plant Biol.2022, 22(1):128.
  • J of Pharmaceutical Analysis2020, doi: 10.1016
  • J Sep Sci.2018, 41(9):1938-1946
  • Planta Med.2018, 84(6-07):465-474
  • Forensic Sci Int.2022, 341:111475.
  • Neurochem Int.2020, 133:104629
  • Chem Biol Interact.2018, 283:59-74
  • J Ethnopharmacol.2017, 209:305-316
  • Bulletin of Health Research2016, 44(4):279-286
  • Mutlu Yanic S, Ates EG. JOTCSA.2023, 10(4);893-902.
  • ...
  • 生物活性
    Description: Isoscoparin has antioxidant, and anti-adipogenic effects, it may be a potential therapeutic agent for the prevention and treatment of obesity. Isoscoparin can significantly inhibit the production of both NO and TNF-α at a concentration of 2.0 uM.
    Targets: Fatty Acid Synthase | NO | TNF-α
    In vitro:
    Food Chem. 2018 Feb 15;241:154-162.
    Identification and quantification of flavonoids in yellow grain mutant of rice (Oryza sativa L.).[Pubmed: 28958514]
    Flavonoids are naturally occurring phenolic compounds with potential health-promoting activities. Although anthocyanins and phenolic acids in coloured rice have been investigated, few studies have focused on flavonoids.
    METHODS AND RESULTS:
    Herein, we analysed flavonoids in a yellow grain rice mutant using UHPLC-DAD-ESI-Q-TOF-MS, and identified 19 flavonoids by comparing retention times and accurate mass measurements. Among them, six flavonoids, isoorientin, isoorientin 2″-O-glucoside, vitexin 2″-O-glucoside, isovitexin, isoscoparin 2″-O-glucoside and isoscoparin, were isolated and fully identified from the yellow grain rice mutant, and the levels were significantly higher than wild-type, with isoorientin particularly abundant in mutant embryo. Significant differences in total phenolic compounds and antioxidant activity were observed in mutant rice by DPPH, FRAP and TEAC assays.
    CONCLUSIONS:
    The results suggest that the representative six flavonoids may play an important role in colouration and antioxidant activity of embryo and endosperm tissue. The findings provide insight into flavonoid biosynthesis and the possibility of improving functionality in rice.
    Phytother Res. 2014 Jul;28(7):1064-70.
    A new phenolic component from Triticum aestivum sprouts and its effects on LPS-stimulated production of nitric oxide and TNF-α in RAW 264.7 cells.[Pubmed: 25165783]
    An unusual new phenolic component, triticumoside (1), and eight known compounds, isoorientin (2), isoscoparin (3), (2R)-2-O-β-D-glucopyranosyloxy-4,7-dimethoxy-2H-1,4-benzoxazin-3(4H)-one (4), adenosine (5), β-sitosterol (6), daucosterol (7), 6′-O-linolenoyl daucosterol (8), α-tocopherol (9), were isolated fromTriticum aestivum sprouts.
    METHODS AND RESULTS:
    The hybrid structure of 1, which is a hybrid between a flavone and a polyoxygenated benzene, is rarely found in natural sources. In addition, the effects of these compounds on LPS-induced NO and TNF-α production in RAW 264.7 cells were evaluated. At a concentration of 2.0 μM, compounds 2-4 significantly inhibited the production of both NO and TNF-α. Compound 1 exhibited inhibitory activity on the secretion of TNF-α at concentrations as low as 2.0 μM, but it did not reduce NO levels at any of the tested concentrations.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1626 mL 10.8131 mL 21.6263 mL 43.2526 mL 54.0657 mL
    5 mM 0.4325 mL 2.1626 mL 4.3253 mL 8.6505 mL 10.8131 mL
    10 mM 0.2163 mL 1.0813 mL 2.1626 mL 4.3253 mL 5.4066 mL
    50 mM 0.0433 mL 0.2163 mL 0.4325 mL 0.8651 mL 1.0813 mL
    100 mM 0.0216 mL 0.1081 mL 0.2163 mL 0.4325 mL 0.5407 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    荭草素-2〞-O-β-L-半乳糖苷; 2''-O-Beta-L-Galorientin CFN93096 861691-37-4 C27H30O16 = 610.5 20mg QQ客服:2056216494
    刺苞菊甙; Carlinoside CFN90720 59952-97-5 C26H28O15 = 580.5 5mg QQ客服:2056216494
    异刺苞菊甙; Isocarlinoside CFN95092 83151-90-0 C26H28O15 = 580.5 5mg QQ客服:2159513211
    光牡荆素II; Lucenin II CFN80138 29428-58-8 C27H30O16 = 610.5 5mg QQ客服:215959384
    金雀花苷; Scoparin CFN95544 301-16-6 C22H22O11 = 462.4 5mg QQ客服:1457312923
    异金雀花素; Isoscoparin CFN90965 20013-23-4 C22H22O11 = 462.40 10mg QQ客服:1457312923
    异金雀花素-2''-Beta-D-吡喃葡萄糖苷; Isoscoparin-2''-Beta-D-glucopyranoside CFN90900 97605-25-9 C28H32O16 = 624.54 5mg QQ客服:215959384
    4'-O-甲基光牡荆素II; 4'-O-Methyllucenin II (Diosmetin 6,8-di-C-glucoside) CFN95344 98813-28-6 C28H32O16 = 624.6 10mg QQ客服:1413575084
    白杨素 6-C-葡萄糖 8-C-阿拉伯糖苷; Chrysin 6-C-glucoside 8-C-arabinoside CFN92285 185145-34-0 C26H28O13 = 548.5 5mg QQ客服:3257982914
    白杨素 8-C-葡萄糖苷; Chrysin 8-C-glucoside CFN91992 160880-89-7 C21H20O9 = 416.38 5mg QQ客服:3257982914

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