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  • 丹芝酸B

    Ganolucidic acid B

    丹芝酸B
    产品编号 CFN95513
    CAS编号 98683-75-1
    分子式 = 分子量 C30H46O6 = 502.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruit body of Ganoderma lucidum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    丹芝酸B CFN95513 98683-75-1 1mg QQ客服:2056216494
    丹芝酸B CFN95513 98683-75-1 5mg QQ客服:2056216494
    丹芝酸B CFN95513 98683-75-1 10mg QQ客服:2056216494
    丹芝酸B CFN95513 98683-75-1 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Chromatogr B Analyt Technol Biomed Life Sci.2021, 1187:123012.
  • Anal Biochem.2019, 569:10-15
  • Metabolites.2020, 11(1):E11.
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  • Arch Biochem Biophys.2020, 687:108384.
  • Phytochem Anal.2013, 24(5):493-503
  • Processes2021, 9(5),831.
  • Evid Based Complement Alternat Med.2020, 2020:8582318.
  • J Control Release.2021, 336:159-168.
  • Molecules. 2013, 18(11):14105-21
  • Appl Microbiol Biotechnol.2018, 102(12):5105-5120
  • Molecules.2023, 28(8):3414.
  • Chem Biol Interact.2016, 260:168-175
  • Front Pharmacol.2021, 12:765521.
  • Antioxidants (Basel).2022, 11(12):2411.
  • Appl Microbiol Biotechnol.2016, 100(9):3965-77
  • Evid Based Complement Alternat Med.2021, 2021:6687513.
  • ...
  • 生物活性
    Description: Ganolucidic acids B showd induction ability of hPXR-mediated CYP3A4 expression.
    In vitro:
    Planta Med . 2012 Mar;78(4):368-376.
    Isolation and bioactivity evaluation of terpenoids from the medicinal fungus Ganoderma sinense[Pubmed: 22161763]
    A new pentanorlanostane, ganosineniol A (1), eight new lanostane triterpenoids, ganosinoside A (2), ganoderic acid Jc (3), ganoderic acid Jd (4), ganodermatetraol (5), ganolucidic acid γa (6), ganolucidate F (7), ganoderiol J ( 8), and methyl lucidenate Ha ( 9), and a new sesquiterpenoid, ganosinensine (10), together with eleven known triterpenoids (11- 21), were isolated from the fruiting bodies of the fungus Ganoderma sinense. Chemical structures were determined based on spectroscopic evidence, including 1D, 2D NMR, and mass spectral data. Furthermore, all isolates were tested for cytotoxic activity and induction ability of hPXR-mediated CYP3A4 expression. Among them, ganoderic acid Jc (3) displayed selective inhibitory activity against HL-60 cells (IC₅₀ = 8.30 μM), and ganoderiol E (11) exhibited selective cytotoxic activity against MCF-7 cells (IC₅₀ = 6.35 μM). Meanwhile, compounds 5, 7, and ganolucidic acids B and C (19, 20) showed induction ability of hPXR-mediated CYP3A4 expression.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.9893 mL 9.9463 mL 19.8926 mL 39.7852 mL 49.7315 mL
    5 mM 0.3979 mL 1.9893 mL 3.9785 mL 7.957 mL 9.9463 mL
    10 mM 0.1989 mL 0.9946 mL 1.9893 mL 3.9785 mL 4.9731 mL
    50 mM 0.0398 mL 0.1989 mL 0.3979 mL 0.7957 mL 0.9946 mL
    100 mM 0.0199 mL 0.0995 mL 0.1989 mL 0.3979 mL 0.4973 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    灵芝酸C2; Ganoderic acid C2 CFN92054 103773-62-2 C30H46O7 = 518.7 20mg QQ客服:1413575084
    灵芝酸A; Ganoderic acid A CFN92051 81907-62-2 C30H44O7 = 516.7 20mg QQ客服:2159513211
    灵芝酸A甲酯; Methyl ganoderate A CFN95550 105742-78-7 C31H46O7 = 530.7 5mg QQ客服:1413575084
    赤芝酸G甲酯; Methyl lucidenate G CFN95058 102607-20-5 C28H42O7 = 490.6 5mg QQ客服:2159513211
    灵芝酸C1; Ganoderic acid C1 CFN92053 95311-97-0 C30H42O7 = 514.7 5mg QQ客服:215959384
    灵芝酸LM2; Ganoderic acid LM2 CFN90297 508182-41-0 C30H42O7 = 514.66 10mg QQ客服:1413575084
    灵芝烯酸G; Ganoderenic acid G CFN95517 120481-73-4 C30H40O7 = 512.6 5mg QQ客服:1413575084
    灵芝酸 J; Ganoderic acid J CFN95516 100440-26-4 C30H42O7 = 514.7 10mg QQ客服:1457312923
    灵芝酸D; Ganoderic acid D CFN90292 108340-60-9 C30H42O7 = 514.66 20mg QQ客服:2159513211
    灵芝酸D甲酯; Methyl ganoderate D CFN95581 97210-12-3 C31H44O7 = 528.7 5mg QQ客服:1457312923

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