补骨脂香豆素A
Ficusin A
|
|
产品编号 |
CFN99817 |
| CAS编号 |
173429-83-9 |
| 分子式 = 分子量 |
C25H24O5 = 404.5 |
| 产品纯度 |
>=98% |
| 物理属性 |
Yellow powder |
| 化合物类型 |
Flavonoids |
| 植物来源 |
The seeds of Psoralea corylifolia Linn. |
| ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 |
|
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| 补骨脂香豆素A |
CFN99817 |
173429-83-9 |
1mg |
QQ客服：215959384 |
| 补骨脂香豆素A |
CFN99817 |
173429-83-9 |
5mg |
QQ客服：215959384 |
| 补骨脂香豆素A |
CFN99817 |
173429-83-9 |
10mg |
QQ客服：215959384 |
| 补骨脂香豆素A |
CFN99817 |
173429-83-9 |
20mg |
QQ客服：215959384 |
1. 在您收到产品后请检查产品。如无问题，请将产品存入冰霜并且样品瓶保持密封，产品可以存放长达24个月（2-8摄氏度）。
2. 只要有可能，产品溶解后，您应该在同一天应用于您的实验。 但是，如果您需要提前做预实验，或者需要全部溶解，我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常，这些可用于长达两周。 使用前，打开样品瓶前，我们建议您将产品平衡至室温至少1小时。
3. 需要更多关于溶解度，使用和处理的建议？ 请发送电子邮件至：service@chemfaces.com
订购流程
1. 在线订购
请联系我们QQ客服
2. 电话订购
请拨打电话：
027-84237683 或 027-84237783
3. 邮件或传真订购
发送电子邮件到: manager@chemfaces.com 或
发送传真到：027-84254680
提供订购信息
为了方便客户的订购，请需要订购ChemFaces产品的客户，在下单的时候请提供下列信息，以供我们快速为您建立发货信息。
1. 产品编号（CAS No.或产品名称）
2. 发货地址
3. 联系方法 (联系人，电话）
4. 开票抬头 (如果需要发票的客户）
5. 发票地址（发货地址与发票地址不同）
发货时间
1. 付款方式为100%预付款客户，我们将在确认收到货款后当天或1-3个工作日发货。
2. 付款方式为月结的客户，我们承诺在收到订单后当天或1-3个工作日内发货。
3. 如果客户所需要的产品，需要重新生产，我们有权告知客户，交货时间需要延期。
ChemFaces的产品在许多优秀和顶级科学期刊中被引用
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
Uniwersytet Gdański (Poland)
The Australian National University (Australia)
University of Hertfordshire (United Kingdom)
VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
Wageningen University (Netherlands)
Subang Jaya Medical Centre (Malaysia)
Weizmann Institute of Science (Israel)
Aarhus University (Denmark)
Agricultural Research Organization (ARO) (Israel)
National Hellenic Research Foundation (Greece)
National Cancer Institute (USA)
The Institute of Cancer Research (United Kingdom)
Melbourne University (Australia)
Max-Planck-Insitut (Germany)
More...
国外学术期刊发表的引用ChemFaces产品的部分文献
| Description: |
Ficusin has antioxidant, antilipidemic and antidiabetic effects, it can lower the levels of fasting blood glucose, plasma insulin, body weight gain in HFD-STZ induced diabetic rats, and can significantly enhance the PPARγ expression and improve the translocation and activation of GLUT4 in the adipose tissue, suggests that ficusin improves the insulin sensitivity on adipose tissue and it can be used for the treatment of obesity related type 2 diabetes mellitusl. |
| Targets: |
GLUT | PPAR |
| In vivo: |
| Chem. Biol. Interact.,2016,256:85-93. | | Antioxidant, antilipidemic and antidiabetic effects of ficusin with their effects on GLUT4 translocation and PPARγ expression in type 2 diabetic rats.[Reference: WebLink] | In this study, the antioxidant, antilipidemic and antidiabetic effects of ficusin isolated from Ficus carica leaves and their effects on GLUT4 translocation and PPARγ expression were evaluated in HFD-STZ induced type 2 diabetic rats.
METHODS AND RESULTS:
Ficusin (20 and 40 mg/kg b. wt.) lowered the levels of fasting blood glucose, plasma insulin and body weight gain, in HFD-STZ induced diabetic rats. Ficusin Also significantly lowered the serum antioxidant enzymes (SOD, CAT and GPx) and lipids (TC, TG and FFA) levels to near normal. Ficusin significantly enhanced the PPARγ expression and improved the translocation and activation of GLUT4 in the adipose tissue. Molecular docking analysis exhibited promising interactions of GLUT4 and PPARγ into their active sites.
CONCLUSIONS:
This study suggests that ficusin improved the insulin sensitivity on adipose tissue and it can be used for the treatment of obesity related type 2 diabetes mellitus. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.4722 mL |
12.3609 mL |
24.7219 mL |
49.4438 mL |
61.8047 mL |
| 5 mM |
0.4944 mL |
2.4722 mL |
4.9444 mL |
9.8888 mL |
12.3609 mL |
| 10 mM |
0.2472 mL |
1.2361 mL |
2.4722 mL |
4.9444 mL |
6.1805 mL |
| 50 mM |
0.0494 mL |
0.2472 mL |
0.4944 mL |
0.9889 mL |
1.2361 mL |
| 100 mM |
0.0247 mL |
0.1236 mL |
0.2472 mL |
0.4944 mL |
0.618 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
部分图片展示
联系方式
电机：027-84237783
传真：027-84254680
在线QQ: 1413575084
E-Mail：manager@chemfaces.com
湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房
ChemFaces为科学家，科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证
天然化合物与对照品的研发和生产。
