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  • 中药标准品生产商,产品定制服务
  • 欧天芥菜碱

    Europine

    欧天芥菜碱
    产品编号 CFN00264
    CAS编号 570-19-4
    分子式 = 分子量 C16H27NO6 = 329.39
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 The herbs of Cynoglossum officinale L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    欧天芥菜碱 CFN00264 570-19-4 1mg QQ客服:2159513211
    欧天芥菜碱 CFN00264 570-19-4 5mg QQ客服:2159513211
    欧天芥菜碱 CFN00264 570-19-4 10mg QQ客服:2159513211
    欧天芥菜碱 CFN00264 570-19-4 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Kyoto University (Japan)
  • Kamphaengphet Rajabhat University (Thailand)
  • Helmholtz Zentrum München (Germany)
  • Anna University (India)
  • Tohoku University (Japan)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Seoul National University of Science and Technology (Korea)
  • Universita' Degli Studi Di Cagliari (Italy)
  • Northeast Normal University Changchun (China)
  • Center for protein Engineering (CIP) (Belgium)
  • Universidade de Franca (Brazil)
  • Indian Institute of Science (India)
  • University of Eastern Finland (Finland)
  • Institute of Tropical Disease Universitas Airlangga (Indonesia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Nutrients.2018, 10(10)
  • Mol Med Rep.2022, 25(1):8.
  • Chem Biol Interact.2016, 260:168-175
  • Drug Des Devel Ther.2020, 14:969-976.
  • J Chromatogr B Analyt Technol Biomed Life Sci.2020, 1149:122123.
  • Journal of Physiology & Pathology in Korean Medicine.2018, 32(2): 106-112
  • Phytochem Anal.2023, pca.3305.
  • Vet World.2023, 16(3):618-630.
  • Br J Pharmacol.2016, 173(2):396-410
  • Molecules.2019, 24(23):E4303
  • Plants (Basel).2022, 11(16):2126.
  • Planta Med.2019, 85(4):347-355
  • Nutr Res Pract.2020, 14(5):478-489.
  • Exp Parasitol.2017, 183:160-166
  • J Cell Mol Med.2023, 27(11):1592-1602.
  • Journal of Functional Foods2017, 30:30-38
  • Front Pharmacol.2019, 10:1355
  • Mol Cell.2017, 68(4):673-685
  • Phytomedicine.2020, 79, 153351
  • J Ethnopharmacol.2017, 206:73-77
  • Molecules.2020, 25(18):4283.
  • Tissue Cell.2022, 78:101901.
  • Agronomy2023, 13(6), 1435.
  • ...
  • 生物活性
    Description: Europine shows both antifungal and insect antifeedant activity.
    Targets: Antifection
    In vivo:
    Vet Hum Toxicol. 2003 Aug;45(4):198-201.
    Toxicity of dietary Heliotropium circinatum to rats.[Pubmed: 12882490]

    METHODS AND RESULTS:
    Pyrrolizidine alkaloid intoxication was produced in adult, male rats by feeding different levels (0, 1, 3, 5 or 10%) of Heliotropium circinatum for 20 w. Combined GC-MS revealed 0.15% total alkaloid content in the plant material of which 12% and 88% were basic and N-oxide forms, respectively. The specific alkaloids identified were Europine (67.33%), heliotrine (16.34%), lasiocarpine (8.12%), heleurine (4.18%), echinatine (1.56%), 7-angeylheliotrine (1.19%), and an unknown alkaloid (1.28%). Neither mortality nor significant clinical changes occurred in test groups. Mild to moderate, dose-related hepatic megalocytosis was the most prominent histopathological finding. In addition to chronic hepatotoxicity, notable medial thickening occurred in the pulmonary arterioles and arteries of the high-dosed groups.
    CONCLUSIONS:
    This study indicated that H. circinatum plant has limited toxic potential in rats with mild to moderate histological changes and no mortality at the dosing levels, total doses, or time of exposure employed.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.0359 mL 15.1796 mL 30.3591 mL 60.7183 mL 75.8979 mL
    5 mM 0.6072 mL 3.0359 mL 6.0718 mL 12.1437 mL 15.1796 mL
    10 mM 0.3036 mL 1.518 mL 3.0359 mL 6.0718 mL 7.5898 mL
    50 mM 0.0607 mL 0.3036 mL 0.6072 mL 1.2144 mL 1.518 mL
    100 mM 0.0304 mL 0.1518 mL 0.3036 mL 0.6072 mL 0.759 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    天芥菜品碱N-氧化物; Heliosupine N-oxide CFN00454 31701-88-9 C20H31NO8 = 413.5 5mg QQ客服:2056216494
    乙酰天芥菜品碱; Acetylheliosupine CFN00269 31514-30-4 C22H33NO8 = 439.50 5mg QQ客服:215959384
    天芥菜碱; Heliotrine CFN00270 303-33-3 C16H27NO5 = 313.39 5mg QQ客服:2159513211
    天芥菜碱 N-氧化物; Heliotrine N-oxide CFN00271 6209-65-0 C16H27NO6 = 329.39 5mg QQ客服:2056216494
    大叶千里光碱; Macrophylline CFN00275 27841-97-0 C13H21NO3 = 239.31 5mg QQ客服:1457312923
    欧天芥菜碱; Europine CFN00264 570-19-4 C16H27NO6 = 329.39 5mg QQ客服:2159513211
    欧天芥菜碱氮氧化物; Europine N-oxide CFN00265 65582-53-8 C16H27NO7 = 345.39 5mg QQ客服:2056216494
    阔叶碱; Latifoline CFN00266 6029-86-3 C20H27NO7 = 393.44 5mg QQ客服:1413575084
    阔叶碱N-氧化物; Latifoline N-oxide CFN00267 98752-06-8 C20H27NO8 = 409.43 5mg QQ客服:1457312923
    天芥菜品碱; Heliosupine CFN00268 32728-78-2 C20H31NO7 = 397.47 5mg QQ客服:2159513211

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