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  • Cucumegastigmane I

    Cucumegastigmane I

    Cucumegastigmane I
    产品编号 CFN97498
    CAS编号 929881-46-9
    分子式 = 分子量 C13H20O4 = 240.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Sesquiterpenoids
    植物来源 The fruits of Trichosanthes kirilowii Maxim
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Cucumegastigmane I CFN97498 929881-46-9 1mg QQ客服:1457312923
    Cucumegastigmane I CFN97498 929881-46-9 5mg QQ客服:1457312923
    Cucumegastigmane I CFN97498 929881-46-9 10mg QQ客服:1457312923
    Cucumegastigmane I CFN97498 929881-46-9 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Wisconsin-Madison (USA)
  • Institute of Tropical Disease Universitas Airlangga (Indonesia)
  • Julius Kühn-Institut (Germany)
  • Universidade da Beira Interior (Germany)
  • University of Illinois (USA)
  • University of Hertfordshire (United Kingdom)
  • Medizinische Universit?t Wien (Austria)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • Ain Shams University (Egypt)
  • Ateneo de Manila University (Philippines)
  • Rio de Janeiro State University (Brazil)
  • Korea Food Research Institute(KFRI) (Korea)
  • Vin?a Institute of Nuclear Sciences (Serbia)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Environ Toxicol.2020, doi: 10.1002
  • Mol Cell.2017, 68(4):673-685
  • Pharmacol Res.2020, 161:105205.
  • Molecules.2020, 25(18),4089.
  • Saf Health Work.2019, 10(2):196-204
  • Front Pharmacol.2021, 12:607403.
  • LWT2021, 138:110630.
  • J Ethnopharmacol.2019, 244:112074
  • Biomed Pharmacother.2020, 131:110673.
  • J of the Korean Society of Cosmetics and Cosmetology2018, 399-406
  • Am J Chin Med.2016, 44(6):1255-1271
  • Eur J Pharmacol.2020, 889:173589.
  • Cancers (Basel).2021, 13(9):2223.
  • Antioxidants (Basel).2020, 9(6):466.
  • Phytomedicine2022, 104:154337.
  • J Bone Miner Res.2017, 32(12):2415-2430
  • Pharmaceuticals.2022, 15(4), 402.
  • Food Chem.2019, 274:345-350
  • Int Immunopharmacol.2021, 100:108073.
  • Chemistry of Natural Compounds2020, 56,423-426
  • Biomedicines.2021, 9(8):954.
  • Clin Transl Oncol.2019, 10.1007
  • Phytother Res.2016, 30(12):2020-2026
  • ...
  • 生物活性
    Description: Standard reference
    In vitro:
    Pharm Biol. 2015 Nov;53(11):1602-7.
    Chemical constituents of the Annona glabra fruit and their cytotoxic activity.[Pubmed: 25856711]

    METHODS AND RESULTS:
    One new, (2E,4E,1'R,3'S,5'R,6'S)-dihydrophaseic acid 1,3'-di-O-β-d-glucopyranoside, and eight known compounds, (2E,4E,1'R,3'S,5'R,6'S)-dihydrophaseic acid 3'-O-β-d-glucopyranoside (2), icariside D2 (3), icariside D2 6'-O-β-d-xylopyranoside (4), 3,4-dimethoxyphenyl O-β-d-glucopyranoside (5), 3,4-dihydroxybenzoic acid (6), blumenol A (7), Cucumegastigmane I (8), and icariside B1 (9), were isolated from the fruits of A. glabra.
    CONCLUSIONS:
    Icariside D2 (3) was found to show significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 µM and did not show cytotoxic activity on the Hel-299 normal cell line.
    Fitoterapia. 2013 Jan;84:227-36.
    Phytochemical and therapeutic potential of cucumber.[Pubmed: 23098877]
    The fruit is refrigerant, haemostatic, tonic and useful in hyperdipsia, thermoplegia etc. The seeds also have a cooling effect on the body and they are used to prevent constipation.
    METHODS AND RESULTS:
    Several bioactive compounds have been isolated from cucumber including cucurbitacins, Cucumegastigmane I and Cucumegastigmane II, cucumerin A and B, vitexin, orientin, isoscoparin 2″-O-(6‴-(E)-p-coumaroyl) glucoside, apigenin 7-O-(6″-O-p-coumaroylglucoside) etc. Despite huge exploration of cucumber in agricultural field, comparatively very few studies have been published about its chemical profile and its therapeutic potential. This article reviews the therapeutic application, pharmacological and phytochemical profile of different parts of C. sativus.
    CONCLUSIONS:
    In this review we have explored the current phytochemical and pharmacological knowledge available with this well known plant and several promising aspects for research on cucumber.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.1615 mL 20.8073 mL 41.6146 mL 83.2293 mL 104.0366 mL
    5 mM 0.8323 mL 4.1615 mL 8.3229 mL 16.6459 mL 20.8073 mL
    10 mM 0.4161 mL 2.0807 mL 4.1615 mL 8.3229 mL 10.4037 mL
    50 mM 0.0832 mL 0.4161 mL 0.8323 mL 1.6646 mL 2.0807 mL
    100 mM 0.0416 mL 0.2081 mL 0.4161 mL 0.8323 mL 1.0404 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    淫羊藿次甙 B1 ; Icariside B1 CFN96968 109062-00-2 C19H30O8 = 386.44 5mg QQ客服:2056216494
    二氢菜豆酸; Dihydrophaseic acid CFN98657 41756-77-8 C15H22O5 = 282.3 5mg QQ客服:1413575084
    二氢菜豆酸 4'-O-葡萄糖苷; Dihydrophaseic acid 4'-O-beta-D-glucopyranoside CFN95393 78914-56-4 C21H32O10 = 444.5 5mg QQ客服:2159513211
    8'-Oxo-6-hydroxydihydrophaseic acid ; 8'-Oxo-6-hydroxydihydrophaseic acid CFN96741 1388075-44-2 C15H20O7 = 312.31 5mg QQ客服:215959384
    脱落酸; Abscisic acid CFN90051 21293-29-8 C15H20O4 = 264.32 20mg QQ客服:2056216494
    8'-O-(3-hydroxy-3-methylglutaryl)-8'-hydroxyabscisic acid; 8'-O-(3-hydroxy-3-methylglutaryl)-8'-hydroxyabscisic acid CFN95308 69790-31-4 C21H28O9 = 424.4 5mg QQ客服:2056216494
    Breyniaionoside A; Breyniaionoside A CFN96810 823182-23-6 C19H32O9 = 404.45 5mg QQ客服:215959384
    Cucumegastigmane I; Cucumegastigmane I CFN97498 929881-46-9 C13H20O4 = 240.3 5mg QQ客服:215959384
    罗布麻酚A; Apocynol A CFN97750 358721-33-2 C13H20O3 = 224.30 5mg QQ客服:3257982914
    7-巨豆烯-3,5,6,9-四醇; Megastigm-7-ene-3,5,6,9-tetraol CFN98335 680617-50-9 C13H24O4 = 244.3 5mg QQ客服:2056216494

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