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  • 剑叶龙血素C

    Cochinchinenin C

    剑叶龙血素C
    产品编号 CFN98503
    CAS编号 956103-79-0
    分子式 = 分子量 C33H34O7 = 542.62
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Chalcones
    植物来源 From Daemonorops draco Bl.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    剑叶龙血素C CFN98503 956103-79-0 1mg QQ客服:3257982914
    剑叶龙血素C CFN98503 956103-79-0 5mg QQ客服:3257982914
    剑叶龙血素C CFN98503 956103-79-0 10mg QQ客服:3257982914
    剑叶龙血素C CFN98503 956103-79-0 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

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    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
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    IF=13.297(2019)

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  • ...
  • 生物活性
    Description: There is a synergistic interaction between loureirin A and Cochinchinenin C, and the fluorescence quenching of HSA by loureirin A (or Cochinchinenin C) is a combined quenching procedure (dynamic and static quenching).
    In vitro:
    Eur J Med Chem. 2015 Mar 26;93:492-500.
    Comparison between loureirin A and cochinchinenin C on the interaction with human serum albumin.[Pubmed: 25734332]

    METHODS AND RESULTS:
    The interactions of loureirin A (LA) and Cochinchinenin C (CC) with human serum albumin (HSA) under simulated physiological conditions (pH = 7.4) have been studied with fluorescence, UV-vis absorption spectroscopic method and molecular docking technique. The results indicated that there was a synergistic interaction between LA and Cochinchinenin C, and the fluorescence quenching of HSA by LA (or Cochinchinenin C) was a combined quenching procedure (dynamic and static quenching). At low compound concentrations, the quenching constants KSV of Cochinchinenin C was larger than that of LA, which meant the Cochinchinenin C efficacy may be better than that of LA. The negative △H and △S values suggested hydrogen bonds and van der Waals forces played the major role in the binding of LA (or Cochinchinenin C) to HSA.
    CONCLUSIONS:
    The efficiency of energy transfer and distance between the compounds and HSA was calculated. Moreover, the results of synchronous and three-dimensional fluorescence demonstrated that the HSA microenvironment was changed in the presence of LA (or Cochinchinenin C). Finally, the binding of LA (or Cochinchinenin C) to HSA was modeled by molecular docking, which is in good accordance with the experimental studies.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8429 mL 9.2146 mL 18.4291 mL 36.8582 mL 46.0728 mL
    5 mM 0.3686 mL 1.8429 mL 3.6858 mL 7.3716 mL 9.2146 mL
    10 mM 0.1843 mL 0.9215 mL 1.8429 mL 3.6858 mL 4.6073 mL
    50 mM 0.0369 mL 0.1843 mL 0.3686 mL 0.7372 mL 0.9215 mL
    100 mM 0.0184 mL 0.0921 mL 0.1843 mL 0.3686 mL 0.4607 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Calyxin H; Calyxin H CFN98024 202596-22-3 C35H34O7 = 566.7 5mg QQ客服:1413575084
    剑叶龙血素A; Cochinchinenin A CFN90769 221696-69-1 C17H18O4 = 286.3 20mg QQ客服:3257982914
    剑叶龙血素C; Cochinchinenin C CFN98503 956103-79-0 C33H34O7 = 542.62 5mg QQ客服:3257982914
    Sarcandrone A; Sarcandrone A CFN99299 1190225-47-8 C33H30O8 = 554.6 5mg QQ客服:2056216494
    Sarcandrone B; Sarcandrone B CFN99300 1190225-48-9 C33H30O8 = 554.6 5mg QQ客服:2056216494
    Calyxin B; Calyxin B CFN99693 164991-53-1 C35H34O8 = 582.7 5mg QQ客服:1413575084
    Galanganone A; Galanganone A CFN89196 1922129-42-7 C32H36O6 = 516.63 5mg QQ客服:1413575084
    Galanganone B; Galanganone B CFN89197 1922129-43-8 C34H40O6 = 544.68 5mg QQ客服:2159513211
    Galanganone C; Galanganone C CFN89198 1922129-46-1 C32H36O5 = 500.63 5mg QQ客服:2056216494

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